HYPERPLASTIC PROCESSES OF ENDOMETRY IN WOMEN IN THE LATE REPRODUCTIVE AND PREMENOPAUZAL PERIOD: WHAT INFLUENCES THE RECURRESTS

Authors

  • S. M. Korniyenko SE Institute pediatrics, obstetrics and gynecology NAMS Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2017.2.8106

Keywords:

gyperplastic processes of the endometrium, premenopause, late reproductive age, relapse, risk factors.

Abstract

Summary. Hyperplastic processes of the endometrium (GPE) occupy a significant place in the structure of gynecological morbidity and are one of the most frequent causes of hospitalization in a gynecological hospital. This pathology causes menstrual irregularities, dysfunctional uterine bleeding and anemia, however, special attention to GPE is associated with a high risk of malignant transformation of the endometrium. Late reproductive age and premenopausal period are associated with a high incidence of relapses of GPE, somatic pathology and gynecological surgeries.

            The aim of the study was to identify factors affecting the recurrence of GPE in women of late reproductive and premenopausal age.

            Materials and methods. Clinical and anamnestic data, personality characteristics, quality of life and long-term results of hysteroscopy in 255 women suffering from GPE at the age of 35-54 years were studied. In 72 women within 1.5-2.5 years after treatment, relapses of GPE were observed. These patients were group P, the remaining 183 women were included in group K. A separate analysis was conducted in groups with polyps and in groups with endometrial hyperplasia.

            Results. Relapses of polyps were observed in 49 (25.5%) cases, endometrial hyperplasia - in 25 (25.3%). Two patients had relapses of both forms of GPE. The level of gynecological incidence in the history of patients with relapses of GPE significantly exceeded the reference values. Urogenital infections did not have a statistically significant effect on the recurrence of endometrial hyperplasia. The effectiveness of polyps, on the contrary, was significantly dependent on genital infections. Somatic diseases more strongly worsened the prospects for treatment of GPE, rather than genital pathology. As personal predictors of recurrent endometrial hyperplasia, neuroticism, spontaneous aggression, depressiveness and emotional lability were noted.

            Conclusions. In the late reproductive and premenopausal age, relapses of GPE are observed in every fourth case. Risks of recurrence of endometrial polyps are most closely associated with anomalies in the development of the uterus, masculine psychotype, chronic endometritis, insomnia, cytomegalovirus genital infection, hypertension and obesity. Chances of recurrence of endometrial hyperplasia most significantly increase liver and thyroid diseases, emotional lability, body mass index over 27 kg / m2, neuroticity, insomnia, depression and autonomic dysfunction syndrome.

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Published

2017-09-26

How to Cite

Korniyenko, S. M. (2017). HYPERPLASTIC PROCESSES OF ENDOMETRY IN WOMEN IN THE LATE REPRODUCTIVE AND PREMENOPAUZAL PERIOD: WHAT INFLUENCES THE RECURRESTS. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (2). https://doi.org/10.11603/1681-2786.2017.2.8106

Issue

No. 2 (2017)

Section

Health of the population:tendencies and forecasts

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