IMPLICATION OF MICROORGANISMS ISOLATED FROM PERIODONTAL POCKETS IN THE PATHOGENESIS OF GENERAL PERIODONTITIS IN PATIENTS WITH GIARDIASIS

Authors

  • N. N. Savel’eva Kharkiv national medical university

DOI:

https://doi.org/10.11603/1681-2786.2016.4.7547

Keywords:

generalized periodontitis, microorganisms, mimicry antigens, giardiasis.

Abstract

The problems of etiopathogenesis of generalized periodontitis of chronic course in persons with parasitic infestation to the present day remain poorly studied.

Purpose. Therefore, the goal of this work was to study the role of microbes isolated from periodontal pockets in the development of generalized periodontitis in persons with giardiasis.

Materials and methods. 120 patients with generalized periodontitis of I-II severity of chronic course were examined with lambliasis (main group). The comparison group consisted of 90 people with GP of I-II severity of chronic course without giardiasis invasion. The control group was represented by 30 persons without pathology of periodontal disease and chronic pathology of other systems, which during the examination period considered themselves to be practically healthy.

Microbiological studies included the isolation and identification of microorganisms using aerobic and anaerobic cultivation techniques.

Statistical processing of materials was carried out using mathematical statistics methods to analyze the data obtained.

Results. It has been shown that antigens of periodontal tissue structures are present in microorganisms colonizing the periodontal pockets of patients with generalized parodontitis of I-II severity against the background of giardiasis.

Сonclusion. Microorganisms of periodontal pockets are not only inducers of banal inflammation in periodontal tissues due to their pathogenic properties (toxin formation, production of enzymes of aggression, etc.), but also serve as a powerful factor that modifies the strength and direction of the immune vector Reaction. The immune response, being by its nature and essence an exclusively protective mechanism of the organism, is capable of becoming a factor of aggression against its own tissues under the influence of microbes expressing tissue antigens of mimicry.

References

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Published

2017-03-23

How to Cite

Savel’eva, N. N. (2017). IMPLICATION OF MICROORGANISMS ISOLATED FROM PERIODONTAL POCKETS IN THE PATHOGENESIS OF GENERAL PERIODONTITIS IN PATIENTS WITH GIARDIASIS. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (4). https://doi.org/10.11603/1681-2786.2016.4.7547

Issue

No. 4 (2016)

Section

Health of the population:tendencies and forecasts

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