State of adaptive reactions in patients with dental diseases in combination with the disorders of gastrointestinal tract
DOI:
https://doi.org/10.11603/2311-9624.2015.2.6270Abstract
Taking into account that one of the causes of the development and chronization of diseases is a violation of adaptive-compensatory reactions in the organism, the aim of this work was to investigate the indices of adaptive reserves in patients with dental diseases, depending on the pathology of gastrointestinal tract. This work is based on the results of observation of 87 patients with odontogenic inflammatory processes and chronic gastroduodenitis or peptic ulcer in anamnesis. To determine the type of adaptive reaction there was investigated the number of leukocytes in peripheral blood and calculated the Differential White Blood Cell Count. The tipping of adaptive reactions (AR) was performed by a classical method of Harkava L. Kh. The obtained data indicate the inferiority of adaptive-compensatory reactions in patients with dental diseases combined with gastric ulcer under the background of moderate and marked anxiety. The course of dental diseases with concomitant chronic gastroduodenitis is characterized by less combativeness than under the background of gastric ulcer and usually is accompanied by nonspecific physiological adaptation reactions.
References
Dolhov V. V. Laboratornaia dyahnostyka narushenyi obmena myneralov y zabolevanyi kostei. Narushenye metabolyzma kaltsyia, fosfora y mahnyia / V. V. Dolhov, Y. P. Ermakova // Osteoporoz y osteopatyy. – 2000. – № 3. – S. 41–48.
Zhenskye polovыe hormonы kak moduliatorы hendernыkh razlychyi v otvete na farmakoterapyiu serdechno-sosudystыkh zabolevanyi / S. N. Tereshchenko, Y. V. Zhyrov, E. S. Krasylnykova, E. Э. Kazantseva // Ratsyonalnaia farmakoterapyia v kardyolohyy. – 2007. – T. 3, № 5. – S. 83–87.
Zhurochko E. Y. Vozmozhnosty kompiuteryzyrovannoi renthenodensytometryy v dyahnostyke strukturno-funktsyonalnoho sostoianyia kostnoi systemы y tkanei parodonta / E. Y. Zhurochko, V. V. Povorozniuk, V. N. Makarenko // Aktualni pytannia klinichnoi medytsyny ta pisliadyplomnoi osvity: nauk.-prakt. konf., 13–14 travnia 2004 r.: tezy dop. – Yalta: KDMU, 2004. – S. 166–167.
Zaidyeva Ya. Z. Hormonalnaia terapyia v klymakteryy : rekomendatsyy dlia klynycheskoi praktyky / Ya. Z. Zaidyeva // Zdorove zhenshchynы. – 2011. – № 7. – C. 98–101.
Zamisna hormonalna terapiia: dumka ukrainskykh spetsialistiv / [pid red. I. Dorosha] // Liky Ukrainy. – 2004. – T. 80, № 3. – S. 84–86.
Kozlova M. V. Remodelyrovanye pry atrofyy alveoliarnoi chasty cheliustei u patsyentov s osteopenycheskym syndromom / M. V. Kozlova, A. M. Panyn, A. M. Mkrtumian // Klynycheskaia herontolohyia. – 2008. – № 2 (14). – S. 30–34.
Makarenko V. N. Osobennosty strukturnoi orhanyzatsyy zubocheliustnoi systemы u zhenshchyn s zabolevanyiamy parodonta v zavysymosty ot strukturno-funktsyonalnoho sostoianyia kostnoi tkany skeleta / V. N. Makarenko // Ukrainskyi morfolohichnyi almanakh. – 2007. – T. 10, № 4. – S. 114–118.
Makarenko V. M. Osoblyvosti likuvannia heneralizovanoho parodontytu u zhinok zi strukturno-funktsionalnymy porushenniamy kistkovoi tkanyny : avtoref. dys. na zdobuttia nauk. stupenia kand. med. nauk : spets. 14.01.22 «Stomatolohiia» / V. M. Makarenko. – K., 2009. – 18 s.
Malychenko S. B. Systemnыe yzmenenyia v klymakteryy. Rol defytsyta kaltsyia y vytamyna D v formyrovanyy postmenopauzalnoho symptomokompleksa / S. B. Malychenko, V. A. Volkova, K. K. Khalydova // Sovremennaia revmatolohyia. – 2008. – № 1. – S. 20–31.
Mashchenko Y. S. Klynycheskye, byokhymycheskye y ymmunolohycheskye aspektы voznyknovenyia nachalnoi stepeny heneralyzovannoho parodontyta / Y. S. Mashchenko, Yu. V. Chernova, Yu. Y. Charun // Visn. stomatolohii. – 2001. – № 3. – S. 8–10.
Melnyk N. S. Osoblyvosti perebihu heneralizovanoho parodontytu pry dysfunktsii shchytopodibnoi zalozy: vplyv na strukturno-funktsionalnyi stan kistkovoi tkanyny alveoliarnoho vidrostka : avtoref. dys. na zdobuttia nauk. stupenia kand. med. nauk : spets. 14.01.22 «Stomatolohiia» / N. S. Melnyk. – K., 2009. – 20 s.
Meretskyi V. M. Morfofunktsionalni osoblyvosti strukturnoi perebudovy kistok skeleta pislia ovariektomii / V. M. Meretskyi, Ya. I. Fedoniuk // Naukovyi visnyk Uzhhorodskoho universytetu. Seriia «Medytsyna». – 2002. – Vyp. 17. – S. 31–35.
Morfometrycheskye yssledovanyia эpytelyotsytov slyzystoi obolochky shcheky krыs posle ovaryoэktomyy y vvedenyia EKSO / A. B. Makedon, Y. N. Moyseev, V. N. Pochtar, V. Ya. Skyba // Visnyk stomatolohii. – 2004. – № 1. – S. 11–15.
Nad Yu. H. Chastota vыiavlenyia androhendefytsyta na fone metabolycheskoho syndroma u muzhchyn, vzaymosviazy s hormonalnыmy narushenyiamy: nauchnoe yzdanye / Yu. H. Nad // Androlohyia y henytalnaia khyrurhyia. – 2011. – № 2. – S. 94–95.
Osteoporoz zubocheliustnoi systemы na fone postmenopauzalnoho systemnoho osteoporoza (obzor lyteraturы) / V. M. Hrynyn, Yu. A. Dorohokuplia, Y. F. Popkova, S. A. Popkov // Stomatolohyia. – 2005. – № 7. – S. 29–34.
Otsenka vlyianyia hysterэktomyy y dvustoronnei ovaryoэktomyy na sostoianye serdechno-sosudystoi systemы / A. N. Andreev, A. V. Akymova, N. V. Yzmozherova [y dr.] // Zhurnal akusherstva y zhenskykh boleznei. – 2006. – T. LV, № 3. – S. 49–53.
Povorozniuk V. V. Antropometrychni indeksy ta ryzyk vynyknennia osteoporotychnykh perelomiv u zhinok v postmenopauzalnomu periodi / V. V. Povorozniuk, O. P. Dmytrenko // Visnyk morfolohii. – 2003. – T. 9, № 2. – S. 422–423.
Povorozniuk V. V. Menopauza y osteoporoz / V. V. Povorozniuk, N. V. Hryhoreva // Reproduktyvnaia эndokrynolohyia : nauchno-praktycheskyi medytsynskyi zhurnal. – 2012. – № 2. – C. 40–47.
Reznykov O. H. Zahalni etychni pryntsypy eksperymentiv na tvarynakh / O. H. Reznykov // Endokrynolohiia. – 2003. – T. 8, № 1. – S. 142–145.
Rybalko L. M. Patohenez osteopenii y osteoporozu v zhinok u pre- i postmenopauzalnomu periodi zhyttia : avtoref. dys. na zdobuttia nauk. stupenia kand. med. nauk : spets. 14.03.04 «Patolohichna fiziolohiia» / L. M. Rybalko. – Donetsk, 2011. – 20 s.
Riznyk Yu. B. Ultrastrukturni porushennia hemomikrotsyrkuliatsii yasen u khvorykh na heneralizovanyi parodontyt / Yu. B. Riznyk, I. V. Chelpanova, O. V. Nakonechna // Praktychna medytsyna. – 2011. – T. 17, № 4. – C. 3–9.
Rosolovska S. O. Vplyv zamisnoi terapii na metabolizm tkanyn parodonta u honadektomovanykh shchuriv riznoi stati / S. O. Rosolovska // Medychna nauka-2011: Vseukrainska naukovo-praktychna konferentsiia : materialy konf. – Poltava, 2011. – S.70.
Smetnyk V. P. Praktycheskye rekomendatsyy po prymenenyiu zamestytelnoi hormonalnoi terapyy u zhenshchyn v pery-y postmenopauze / V. P. Smetnyk // Klymakteryi. – 2005. – № 1. – S. 3–9.
Smyrnov A. V. Myneralnaia plotnost kostnoi tkany u zhenshchyn s revmatoydnыm artrytom v postmenopauzalnom peryode / A. V. Smyrnov // Sovremennaia revmatolohyia. – 2008. – № 1. – S. 48–52.
Udovytskaia E.V. Эndokrynolohycheskye aspektы stomatolohyy / E. V. Udovytskaia. – M. : Medytsyna, 1975. – 181 s.
Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy / F. Ciardiello, R. Bianco, R. Caputo [et al.] // Clin. Cancer Res. – 2004. – Vol. 10, № 2. – P. 784–793.
Banu J. Causes, consequences, and treatment of osteoporosis in men / J. Banu // Drug Des. Devel. Ther. – 2013. – Vol. 7. – P. 849–860.
Bikle D. D. Vitamin D regulation of immune function / D. D. Bikle // Vitam. Horm. – 2011. – Vol. 86. – R. 1–21.
Califano J. V. Periodontal diseases of children and adolescents / J. V. Califano // Pediatr. Dent. – 2007. – Vol. 27, Suppl 7. – P. 189–196.
Correlation study on polymorphisms of vitamin D receptor gene in patients with periodontitis / L. Zhang, H. X. Meng, H. S. Zhao [et al.] // Beijing Da Xue Xue Bao. – 2010. – Vol. 42, № 1. – R. 37–40.
1,25(OH)2D deficiency induces temporomandibular joint osteoarthritis via secretion of senescence-associated inflammatory cytokines / M. Shen, Y. Luo, Y. Niu [et al.] // Bone. – 2013. – Vol. 55, № 2. – P. 400–409.
Effect of coenzyme Q10 on the expression of tumor necrosis factor-α and interleukin-10 in gingival tissue of experimental periodontitis in rats / H. J. Jin, Y. Xue, G. Chen, Z. Y. Wu. // Zhonghua Kou Qiang Yi Xue Za Zhi. – 2013. – Vol. 48, № 11. – R. 660–663.
Elevation of vitamin D-binding protein levels in the plasma of patients with generalized aggressive periodontitis / X. Zhang, H. Meng, X. Sun [et al.] // J. Periodontal Res. – 2013. – Vol. 48, № 1. – P. 74–79.
Estrogen effect on heart rate variability in hypertensive postmenopausal women / O. R. Brito–Zuritaa, C. Posadas–Romerob, A. G. Hermosilloc [et al.] // Maturitas. – 2003. – Vol. 44, № 1. – P. 39–48.
European convention for the protection of vertebrate animals used for experimental and other scientific purposes [Elektronnyi resurs]. – Strasburg, 1986. – Rezhym dostupu: http://conventions.coe.int/Treaty/en/Treaties/Html/123.htm
Geurs N. Osteoporosis and periodontal disease / N. Geurs // Periodontol. – 2007. – Vol. 44, № 1. – R. 29–43.
Gingival crevicular fluid levels of osteoprotegerin (OPG) in premenopausal and postmenopausal women with or without chronic periodontitis / C. Babir, G. Ozcan, D. U. Cebi [et al.] // J. Dent. – 2012. – Vol. 40, № 5. – P. 364–3671.
Hewison M. Vitamin D and innate and adaptive immunity / M. Hewison // Vitam Horm. – 2011. – Vol. 86. – P. 23–62.
Influence of hormonal variation on the periodontium in women / S. Amar, K. M. Chung // Periodontol. – 2000. – Vol. 6, № 1. – P.79–87.
Jagelaviciene E. The relationship between general osteoporosis of the organism and periodontal diseases / E. Jagelaviciene, R. Kubilius // Medicina (Kaunas). – 2006. – Vol. 42, № 8. – P. 613–618.
Khimshiashvili N. B. Expression of parodontal tissue matrix metalloproteinases-1,2 in adolescent and their role in gingival pathology / N. B. Khimshiashvili // Georgian Med. News. – 2013. – Vol. 217. – P. 34–40.
Manukhina E. B. Stress-limiting nitric oxide system / E. B. Manukhina, I. Iu. Malyshev // Ross. Fiziol. Zh. Im. I. M. Sechenova. – 2000. – Vol. 86, № 10. – P. 1283–1292.
Nishimura F. Periodontal disease / F. Nishimura, M. Iwashita, A. Yamashita // Nihon Rinsho. – 2012. – Vol.70, Suppl. 5. – R. 499–502.
Osteoporosis and oral infection: independent risk factors for oral bone loss / R. M. Brennan-Calanan, R. J. Genco, G. E. Wilding [et al.] // J. Dent. Res. – 2008. –Vol. 87, № 4. – R. 323–327.
Osteoporosis, jawbones and periodontal disease / R. Guiglia, O. Di Fede, L. Lo Russo [et al.] // Med. Oral Patol. Oral Cir. Bucal. – 2013. – Vol. 18, № 1. – R. 93-95. Bilezikian [et al.] // Vol. 18, № 1. – R. 93–99.
Periodontal health and caries prevalence evaluation in patients affected by Parkinsons disease [Elektronnyi resurs] / M. Cicci, G. Risitano, G. Lo Giudice, E. Bramanti // Parkinsons Dis. – 2012. – Vol. 2012. – Article ID 541908, 6 pages. – Rezhym dostupu: http://dx.doi.org/10.1155/2012/541908
Response rates to oestrogen treatment in perimenopausal women: 5-year data from The Danish Osreoporosis Prevention Study (DOPS) / L. Rejnmark, P. Vestergaard, C. L. Toffeng [et al.] // Maturitas. – 2004. – Vol. 48, № 3. – P. 307–320.
Rivaldo E. G. Alveolar bone loss and aging: a model for the study in mice / E. G. Rivaldo, D. P. Padilha, F. N. Hugo // J. Periodontol. – 2005. – Vol.76, № 11. – R. 1966–1971.
Scardina G. A. Oral microcirculation in post-menopause: a possible correlation with periodontitis / G. A. Scardina, P. Messina // Gerodontology. – 2012. – Vol. 29, № 2. – R. 1045–1051.
Soory M. Targets for steroid hormone mediated actions of periodontal pathogens, cytokines and therapeutic agents: some implications on tissue turnover in the periodontium / M. Soory // Curr. Drug Targets. – 2000. – Vol. 1, № 4. – P. 309–325.
Supplementation with vitamin D does not increase serum testosterone levels in healthy males / R. Jorde, G. Grimnes, M.S. Hutchinson [et al.] // Horm. Metab. Res. – 2013. – Vol. 45, № 9. – P. 675–681.
The effect of in vitro fertilization on gingival inflammation according to womens periodontal status: clinical data / A. Pavlatou, A. Tsami, N. Vlahos [et al.] // J. Int. Acad. Periodontol. – 2013. – Vol. 15, № 2. – P. 36–42.
The relationship between bone mineral density and periodontitis in postmenopausal women / M. Tezal, J. Wactawski-Wende, S. G. Grossi [et al.] // J. Periodontol. – 2000. – Vol. 71, № 9. – R. 1492–1498.
Verification of IL-17A and IL-17F in oral tissues and modulation of their expression pattern by steroid hormones / A. Konermann, J. Winter, N. Novak [et al.] // Cell Immunol. – 2013. – Vol. 285, № 1–2. – P. 133–140.
Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling [Elektronnyi resurs] / R F. Chun, B. E. Peercy, J. S. Adams, M. Hewison // PLoS One. – 2012. – Vol. 7, № 1.– Rezhym dostupu: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265504/
Zofkova I. Long-term 1,25(OH)2 vitamin D therapy increases bone mineral density in osteopenic women. Comparison with the effect of plain vitamin D / I. Zofkova, M. Hill // Aging Clin. Exp. Res. – 2007. – Vol. 19, № 6. – P. 472–477.
