Comparative assessment of the clinical effectiveness of therapeutic and preventive agents in early childhood caries

Authors

  • Кh. V. Shkliar I. Horbachevsky Ternopil National Medical University
  • O. V. Avdeev I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/2311-9624.2023.2-3.14193

Keywords:

early childhood caries, enamel demineralization, children, remineralizing therapy

Abstract

Summary. Early childhood caries is currently the subject of close attention of researchers due to its significant prevalence and risk of negative consequences for children's health. The use of directed therapeutic and preventive action will contribute to reducing the prevalence and intensity of dental caries in children.

The aim of the study to conduct a comparative assessment of the clinical effectiveness of remineralizing therapy with the use of various therapeutic and preventive agents in the treatment of dental caries in young children.

Materials and Methods. We examined 222 children aged 3 to 6 years, among whom groups of comparison were formed depending on the place of residence, age, and method of therapeutic and preventive measures. The main group was assigned the restorative gel ApaCare "Liquid Enamel" for home use, and the comprarison group was assigned the fluoride varnish "Ivoclar Vivadent Fluor Protector". Clinical examination of the oral cavity was conducted according to the standard scheme, with an assessment of the condition of the teeth and the establishment of a diagnosis according to diagnostic criteria. The intensity of enamel demineralization was evaluated using the 2 % methylene blue staining method on a 10-point Aksamit scale. The indicators of enamel functional resistance were tested according to the enamel resistance test (Okushko V. R.). The investigated indicators were compared at the time of the initial examination and after 12 months of therapeutic and preventive measures.

Results and Discussion. The percentage of children from the examined group who had acute initial caries was 60.36 % (134 individuals). On average, for every examined person, caries in the white spot stage amounted to 2.63 ±0.37 points across the groups. The demineralization intensity of tooth enamel in children aged 3–4 years was determined as a mild level (2–3 scores), in children aged 5–6 years, it was of medium intensity (4–5 scores). The TER demonstrated sufficient enamel resistance in children aged 3–4 years, while in children aged 5–6 years, it showed an average structural-functional enamel resistance. The comparative assessment of the investigated indicators after the implementation of therapeutic and preventive measures demonstrated superior clinical results when applying the protective fluoride varnish "Ivoclar Vivadent Fluor Protector", confirmed by determining the intensity of enamel demineralization and depth.

Conclusions. The implementation of therapeutic and preventive measures for early childhood caries has allowed for a reduction in the intensity and progression of early childhood caries.

References

GBD (2017). Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159), 1789-1858. DOI: 10.1016/S0140-6736(18)32279-7. DOI: https://doi.org/10.1016/S0140-6736(18)32279-7

Resolution WHA 60.17. Oral hygiene: an action plan for advocacy and comprehensive prevention diseases. Sixtieth session World health assembly. Geneva, 14-23 may 2007. [Online]. Retrieved from: https://apps.who.int/gb/ebwha/pdf_files/WHASSA_WHA60-Rec1/E/WHASS1_WHA60REC1-en.

Menghini, G., Steiner, M., & Imfeld, T. (2008). Kleinkinderkaries-Fakten und Vorbeugung [Early childhood caries-facts and prevention]. Ther. Umsch. German., 65(2), 75-82. DOI: 10.1024/0040-5930.65.2.75. PMID: 18517061. DOI: https://doi.org/10.1024/0040-5930.65.2.75

Okushko, V.R. (2013). Nasledstvennyi faktor kariesa v kachestve epigeneticheskogo fenomena [Hereditary factor of caries as an epigenetic phenomenon]. Innovatsii v stomatolohii – Innovations in dentistry, 1, 43-46 [in Russian].

Alazmah, A. (2017). Early Childhood Caries: A Review. J. Contemp. Dent. Pract., 1, 18(8), 732-737. DOI: 10.5005/jp-journals-10024-2116. PMID: 28816199. DOI: https://doi.org/10.5005/jp-journals-10024-2116

Levytskyi, A.P. (2002). Sovremennyie predstavleniya ob etyolohii y patogeneze kariesa zubov [Modern ideas about the etiology and pathogenesis of dental caries]. Visnyk stomatolohii – News of Dentistry, 4, 119-1247 [in Russian].

Khomenko, L.O., Bidenko, N.V., Ostapko, O.I., Holubieva, I.M., Sorochenko, H.V., & Trachuk, Yu.M. (2013). Kontrol nad kariiesom zuba: evoliutsiia kontseptsii [Control over dental caries: evolution of the concept]. Stomatolohyia: ot naukі k praktyke – Stomatology: from science to practice, 1, 53-65 [іn Ukrainian].

Kirthiga, M., Murugan, M., Saikia, A., & Kirubakaran, R. (2019). Risk Factors for Early Childhood Caries: A Systematic Review and Meta-Analysis of Case Control and Cohort Studies. Pediatr. Dent., 41(2), 95-112.

Borutta, A.N., & Smoliar, N.I. (2015). Tendentsii u profilaktytsi kariiesu zubiv z urakhuvanniam zahalnykh faktoriv ryzyku [Trends in dental caries prevention taking into account common risk factors]. Profilaktychna ta dytiacha stomatolohiia – Preventive and pediatric dentistry, 2, 5-8.

Voevoda, E.A., Holubeva, Y.N., & Ostapko, E.Y. (2014). Osobennosti myneralizuiushchei funktsyy sliuny u detei s razlichnoi stepeniu aktyvnosti kariyesa zubov [Features of the mineralizing function of saliva in children with varying degrees of dental caries activity]. Sovremennaia stomatolohyia – Modern dentistry, 1, 79-80 [in Russian].

Ivanchyshyn, V.V. (2010). Morfolohichna kartyna rotovoi ridyny pry pochatkovomu kariiesi postiinykh zubiv u ditei [Morphological pattern of oral fluid in initial caries of permanent teeth in children]. Ukrainskyi stomatolohichnyi almanakh – Ukrainian Dental Almanac, 2, 34-37 [in Ukrainian].

Denha, A.E., & Makarenko, O.A. (2013). Byokhimicheskiye parametry rotovoi zhydkosti u detei s nachalnym kariesom zubov v protsesse kompleksnogo ortodonticheskogo lecheniya [Biochemical parameters of oral fluid in children with initial dental caries during complex orthodontic treatment]. Visnyk stomatolohii – News of Dentistry, 3, 58-62 [in Russian].

Smoliar, N.Y., & Chukhrai, N.L. (2015). Osobennosti myneralizyruiushchei funktsyi rotovoi zhydkosti u detei raznogo vozrasta [Features of the mineralizing function of oral fluid in children of different ages]. Stomatolohycheskiy zhurnal – Dental Journal, 2, 105-108 [in Russian].

Vlasova, H.Y., Onopryenko, N.V., & Starodubtseva D.A. (2010). Remineralyzatsyia emaly na rannikh stadiyakh dekaltsyfikatsii sposobom alternativnym elektroforeza [Remineralization of enamel in the early stages of decalcification using an alternative method to electrophoresis]. Ukrainskyi medychnyi almanakh – Ukrainian Medical Almanac, 13(2), 32-33 [in Russian].

Zadorozhna, I.V., & Povorozniuk, V.V. (2014). Poshyrenist ta intensyvnist kariiesu zubiv u ditei Ukrainy: rezultaty kliniko-epidemiolohichnoho obstezhennia [Prevalence and intensity of dental caries in children of Ukraine: results of a clinical and epidemiological survey]. Bol. Sustavy. Pozvonochnik – Pain. Joints. Spine, 1-2, 26-29 [in Ukrainian]. DOI: https://doi.org/10.22141/2224-1507.1-2.13-14.2014.80058

Ramalingam, L., & Messer, L.B. (2004). Early childhood caries: an update. Singapore Dent. J., 26(1), 21-29. PMID: 15736838.

Pitts, N.B., Twetman, S., Fisher, J., & Marsh, P.D. (2021). Understanding dental caries as a non-communicable disease. Br. Dent. J., 231(12), 749-753. DOI: https://doi.org/10.1038/s41415-021-3775-4

DOI: 10.1038/s41415-021-3775-4. Epub 2021 Dec 17. PMID: 34921271; PMCID: PMC8683371.

Kovach, I.V., Stompel, G.V., Dychko, E.N., & Verbytska, A.V. (2018). Profilaktyka kariyesu zubiv v umovakh zabrudnennya ekolohiyi [Prevention of dental caries in conditions of environmental pollution]. Ukrayinskyy stomatolohichnyy almanakh – Ukrainian Stomatological Almanac, 1, 55-59 [іn Ukrainian]. DOI: https://doi.org/10.31718/2409-0255.1.2018.13

Denga, O.V., Denga, E.M., & Levitskyi, A.P. (1996). Modified pH-test of mixed saliva for rapid assessment of the caries situation: [inform. sheet], 110-96 [in Ukrainian].

Okushko, V.R. (1993). Karіyes: preventіvnaia terapiya – Caries: preventive therapy. Donetsk [in Russian].

Published

2023-10-26

How to Cite

Shkliar К. V., & Avdeev, O. V. (2023). Comparative assessment of the clinical effectiveness of therapeutic and preventive agents in early childhood caries. CLINICAL DENTISTRY, (2-3), 95–101. https://doi.org/10.11603/2311-9624.2023.2-3.14193

Issue

Section

Children’s stomatology