The role of pathogenetic mechanisms in the formation of hypertrofic gingivitis in cildren with epilepsy

Authors

  • N. O. Gevkaliuk I. Horbachevsky Ternopil National Medical University
  • Yu. M. Martyts I. Horbachevsky Ternopil National Medical University
  • V. M. Mykhailiuk I. Horbachevsky Ternopil National Medical University
  • V. Ye. Pudiak I. Horbachevsky Ternopil National Medical University
  • V. Ya. Krupei I. Horbachevsky Ternopil National Medical University
  • M. Ya. Pynda I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/2311-9624.2023.2-3.14192

Keywords:

periodontium, hypertrophic gingivitis, children, epileptic disease

Abstract

Summary. The issue of prevention and treatment of periodontal tissue diseases in children with psychoneurological disorders remains an actual problem in dentistry.

The aim of the study –to study the features of periodontal tissue damage in children with epilepsy.

Materials and Methods. The research was carried out on the base of the Charitable Organization "ROKADA Charitable Fund" (Chortkiv). The main group of the study consisted of 18 children aged 8–10 years, suffering from epilepsy, the control group – children of the same age (n=24). The state of hygiene of the oral cavity and periodontal tissues was determined clinically according to diagnostic criteria.

Results and Discussion. Qualitative assessment of the value of the hygienic index showed that, on average, the hygienic index was 2.03±0.02 points in the group of sick children (1.59±0.23 points in the control group), which indicates an unsatisfactory level of oral hygiene. In the structure of periodontal tissue diseases in children with epilepsy, hypertrophic gingivitis prevailed, the prevalence of which was 61.11±2.34 % among children of the main group, and in 81.82 % of cases among these children, the generalized process prevailed. A month after carrying out sanitary and educational work on rational oral hygiene, professional oral hygiene, antibacterial, anti-inflammatory therapy, the condition of the periodontal tissues improved slightly.

Conclusions. The most effective method of improving the condition of periodontal tissues in children with epilepsy who need life-long antiepileptic drug therapy is the study of pathogenetic mechanisms of this nosology, which prompts their deeper study with priority attention to preventive measures.

References

Ostapko, O.I. (2015). Stan tkanyn parodonta u ditey ta pidlitkiv, yaki prozhyvayut u riznykh rehionakh Ukrayiny [The condition of periodontal tissues in children and adolescents living in different regions of Ukraine]. Novyny stomatolohii – Dentistry News, 1, 78-83 [in Ukrainian].

Gevkaliuk, N.О., Pudiak, V.Ye., & Pynda, M.Ya. (2018). Suchasni uyavlennya pro pjrushennya stanu orhaniv ta tkanyn porognyny rota u ditej i faktory, sho yich vyznachayut «Suchasni zdorovyazberezhuvalni tekhnolohiyi»: monohrafiya [Modern ideas about disorders of the organs and tissues of the oral cavity in children and the factors that caused them "Modern health-saving technologies": monograph]. Kharkiv: KhNPU im. H. S. Skovorody [in Ukrainian].

Smolyar, N.I., & Mashkarynets, A.A. (2015). Poshyrenist khronichnoho kataralnoho hinhivitu u divchat v zalezhnosti vid periodu statevoho dozrivannya [Prevalence of chronic catarrhal gingivitis in girls depending on the period of puberty]. Visnyk stomatolohiyi – Bulletin of Dentistry, 3, 105-108 [in Ukrainian].

WHO releases new report on global problem of oral diseases. World Health Organization, 2009. Available at: http://www.emro.who.int/

Beltran-Aguilar, E.D., & Beltran-Neira, R.J. (2014). Oral diseases and conditions throughout the lifespan. I. Diseases and conditions directly associated with tooth loss. Gen. Dent., 52, 21-27.

Savychuk, N.O. (2008). Stomatolohichne zdorovya ditey, metodolohichni pidkhody ta kryterii otsinky [Children's dental health, methodological approaches and evaluation criteria]. Sovremennaya stomatolohiya – Modern Dentistry, 1, 94-98 [in Ukrainian].

Kosenko, K.N., & Denga, O.V. (2009). Strategiya profilaktiki osnovnykh stomatologicheskikh zabolevaniy s uchetom epidemiologicheskikh osobennostey Ukrainy [Strategy for the prevention of major dental diseases, taking into account the epidemiological characteristics of Ukraine]. Vísnik stomatolohíí̈ – Bulletin of Dentistry, 4, 24-25 [in Ukrainian].

Borysenko, A.V. (2019). Nova klasyfikatsiya zakhvoryuvan parodonta i periimplantnykh staniv [New classification of periodontal diseases and periimplant conditions] Sovremennaya stomatolohyya – Modern Dentistry, 3, 24-27. DOI: 10.33295/1992-576X-2019-3-24 [in Ukrainian].

Altun, C., Guven, G., Yorbik, O., Acikel, C, & Altun, C. (2010). Dental Injuries in Autistic Patients. Pediatr. Dent., 32(4), 343-346.

Du, R.Y., Yiu, C.K., & King, N.M. (2015). Oral health among preschool children with autism spectrum disorders: A case-control study. Autism, 19(6), 746-751. DOI: https://doi.org/10.1177/1362361314553439

Vishnu Rekha, C., Arangannal, P., & Shahed, H. (2012). Oral health status of children with autistic disorder in Chennai. Eur. Arch. Paediatr. Dent., 13(3), 126-131. DOI: https://doi.org/10.1007/BF03262858

Saxena, S., Funk, M., & Chisholm, D. (2014). WHO's Mental Health Action Plan 2013-2020: 107 what can psychiatrists do to facilitate its implementation? World Psychiatry, 13, 2, 107-109. DOI: 10.1002/wps.20141. DOI: https://doi.org/10.1002/wps.20141

Ghafoor, P.A., Rafeeq, M., & Dubey, A. (2014). Assessment of oral side effects of Antiepileptic drugs and traumaticoro-facial injuries encountered in Epileptic children. J. Int. Oral .Health, 6(2), 126-128.

Gurbuz, T., & Tan, H. (2014). Oral health status in epileptic children. Pediatr. Int., 52, 279-283. DOI: https://doi.org/10.1111/j.1442-200X.2009.02965.x

Kanner, A.M., Ashman, E., & Gloss, D. (2018). Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new-onset epilepsy: Report of the American Epilepsy Society and the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr. 18(4), 260-268. DOI: https://doi.org/10.5698/1535-7597.18.4.260

Gautam, A., Verma, P.K., Srivastava, R., & Lodhi, K. (2013). Esthetic Correction of Phenytoin Induced Gingival Hyperplasia- Case Reports. Health Care, 1, 28-31. DOI: https://doi.org/10.12966/hc.08.01.2013

Fisher, R.S., Acevedo, C., & Arzimanoglou, A. (2014). A practical clinical definition of epilepsy. Epilepsia, 55(4), 475-482. DOI: https://doi.org/10.1111/epi.12550

Mehmet, Y., Senem, O., Sülün, T., & Humeyra, K. (2016). Management of Epileptic Patients in Dentistry. Surg. Sci., 3, 47-52. DOI: https://doi.org/10.4236/ss.2012.31008

Kinderen, R.J., Evers, S.M., Rinkens, R., Postulart, D., Vader, C.I., Majoie, M.H., & Aldenkamp, A.P. (2014). Side effects of antiepileptic drugs: The economic burden. Seizure, 23(3), 184-190. DOI: https://doi.org/10.1016/j.seizure.2013.11.009

Kaomongkolgit, R., Tantanapornkul, W., Jittapiromsak, N., Ngamwannagul, P., & Sriaroon, P. (2015). Severe Anti-epileptic Drug-induced Gingival Overgrowth in a Physically Disabled Patient. West Indian Med. J., 65(1), 212-215. DOI: https://doi.org/10.7727/wimj.2014.359

Parks, E.T., & Lancaster, H. (2013). Oral manifestations of systemic disease. Dermatol. Clin., 21, 171-182. DOI: https://doi.org/10.1016/S0733-8635(02)00066-9

Joshipura, V. (2012). Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis. J. Indian Soc. Periodontol., 16(2), 278-281. DOI: https://doi.org/10.4103/0972-124X.99277

Swinson, B., Witherow, H., Norris, P., & Lloyd, T. (2014). Oral manifestations of systemic diseases. Hosp. Med., 65, 92-99. DOI: https://doi.org/10.12968/hosp.2004.65.2.12067

Lindhe, Jan Karring, & Thorkild, Lang, N.P. (2021). Clinical Periodontology and Implant Dentistry. Blackwell Publishing Ltd.

Borysenko, А.V., & Tkachenko, A.H. (2005). Indeksnaia otsenka intensivnosti vospalitelnykh i destruktivnykh izmenenii v tkaniakh parodonta pri generalizovannom parodontite [Index assessment of the intensity of inflammatory and destructive changes in periodontal tissues in generalized periodontitis]. Sovremennaia stomatolohyia – Modern Dentistry [in Russian].

Borysenko, А.V. (2019). Nova klasyfikaziya zachvoryuvan parodonta I periimplantnych staniv [A new classification of periodontal diseases and peri-implant conditions]. Suchasna stomatologiya – Modern Dentistry, 3, 24-27. DOI: https://doi.org/10.33295/1992-576X-2019-3-24

de Jong-Lenters, M., L'Hoir, M., Polak, E., & Duijster D. (2019). Promoting parenting strategies to improve tooth brushing in children: design of a non-randomised cluster-controlled trial. BMC Oral Health, 6, 19(1), 210.

DOI: 10.1186/s12903-019-0902-6. DOI: https://doi.org/10.1186/s12903-019-0902-6

Downloads

Published

2023-10-26

How to Cite

Gevkaliuk, N. O., Martyts, Y. M., Mykhailiuk, V. M., Pudiak, V. Y., Krupei, V. Y., & Pynda, M. Y. (2023). The role of pathogenetic mechanisms in the formation of hypertrofic gingivitis in cildren with epilepsy . CLINICAL DENTISTRY, (2-3), 77–83. https://doi.org/10.11603/2311-9624.2023.2-3.14192

Issue

No. 2-3 (2023)

Section

Children’s stomatology

License

Copyright (c) 2023 CLINICAL DENTISTRY

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.