A RARE TUMOR – ADRENAL ANGIOSARCOMA

(case report)

Authors

DOI:

https://doi.org/10.11603/ijmmr.2413-6077.2022.2.13221

Keywords:

adrenal angiosarcoma, suprarenal, adrenalectomy, vasoformative tumor

Abstract

Background. Primary adrenal angiosarcoma is an exceptionally rare tumor with an incidence of <1% of soft tissue sarcomas. Less than 50 cases being described in literature; most of them were nonfunctional presenting with symptoms of abdominal lump, weight loss, fatigue or weakness. The treatment remains multi-modal with involvement of surgeon as well as medical oncologist.

Objective. The aim of this case report is to describe an entity which is rare in terms of incidence. It was functional as well as metastatic and managed with multimodality therapy.

Methods. The case is a 47-year-old man diagnosed with metastatic adrenal angiosarcoma. The patient was managed with chemotherapy followed by surgery.

Results. The final histopathological examination of the specimen and immunohistochemistry revealed angiosarcoma. At present the patient is under follow-up.

Conclusion. Even though surgery forms the main stay of management, the role of multi-modality therapy forms the cornerstone for adrenal angiosarcomas.

Author Biographies

A. Kumar M., ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

Assistant Professor (Surgery), Armed Forces Medical College, Pune, India

N. Roy, ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

Professor (Surgery), Armed Forces Medical College, Pune, India

H. Jafri, ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

Assistant Professor (Surgery), Armed Forces Medical College, Pune, India

V. Popli, ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

Assistant Professor (Surgery), Armed Forces Medical College, Pune, India Maharashtra, India

 

V. S. Karthik, ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

SR (Surgery), Armed Forces Medical College, Pune, India

T. Phuntsho, ARMED FORCES MEDICAL COLLEGE, PUNE, INDIA

JR (Surgery), Armed Forces Medical College, Pune, India

References

Weiss SW, Goldblum JR, Folpe AL. Enzinger and Weiss’s Soft Tissue Tumors. Elsevier Health Sciences; 2007. 4348 p.

Li XM, Yang H, Reng J, Zhou P, Cheng ZZ, Li Z, et al. A case report of primary adrenal angiosarcoma as depicted on magnetic resonance imaging. Medicine (Baltimore). 2017 Nov 10;96(45):e8551.

https://doi.org/10.1097/MD.0000000000008551

Grajales-Cruz A, Baco-Viera F, Rivé-Mora E, Ramírez-Tanchez C, Tasso D, Arroyo-Portela N, et al. Primary Adrenal Angiosarcoma: A Rare and Potentially Misdiagnosed Tumor. Cancer Control. 2017 Apr;24(2):198-201.

https://doi.org/10.1177/107327481702400213

Stavridis S, Mickovski A, Filipovski V, Sasho B, Sasho D, Ljupcho L. Epithelioid Angiosarcoma of the Adrenal Gland. Report of a Case and Review of the Literature. Maced J Med Sci. 2010 Dec 15;3.

Antao N, Ogawa M, Ahmed Z, Piao J, Poddar N. Adrenal Angiosarcoma: A Diagnostic Dilemma. Cureus. 11(8):e5370.

Kareti LR, Katlein S, Siew S, Blauvelt A. Angiosarcoma of the adrenal gland. Arch Pathol Lab Med. 1988 Nov;112(11):1163-5.

Fuletra JG, Ristau BT, Milestone B, Cooper HS, Browne A, Movva S, et al. Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach. Urol Case Rep. 2016 Dec 1;10:38-41.

https://doi.org/10.1016/j.eucr.2016.11.003

Livaditou A, Alexiou G, Floros D, Filippidis T, Dosios T, Bays D. Epithelioid Angiosarcoma of the Adrenal Gland Associated with Chronic Arsenical Intoxication? Pathol - Res Pract. 1991 Mar 1;187(2): 284-9.

https://doi.org/10.1016/S0344-0338(11)80785-5

Kumar A, Popli V, roy N, Jafri H, Ponnam A. Giant adrenal endothelial Cyst: A case report. Med Sci Int Med J. 2022 Aug 21;11.

https://doi.org/10.5455/medscience.2022.04.102

Sung JY, Ahn S, Kim SJ, Park YS, Choi YL. Angiosarcoma arising within a long-standing cystic lesion of the adrenal gland: a case report. J Clin Oncol Off J Am Soc Clin Oncol. 2013 Mar 20;31(9):e132-6.

https://doi.org/10.1200/JCO.2012.44.0800

Rodriguez-Pinilla SM, Benito-Berlinches AB, Ballestin C, et al. Angiosarcoma of adrenal gland: report of a case and review of the literature. Rev Esp Patol. 2002;35(2):227-32.

Criscuolo M, Valerio J, Gianicolo ME, et al. A vinyl chloride-exposed worker with an adrenal gland angiosarcoma: a case report. Ind Health. 2014; 52(1):66-70.

https://doi.org/10.2486/indhealth.2013-0044

Hendry S, Forrest C. Epithelioid angiosarcoma arising in an adrenal cortical adenoma: a case report and review of the literature. Int J Surg Pathol. 2014;22(8):744-8.

https://doi.org/10.1177/1066896914532541

National Institutes of Health. NIH state-of-the-science statement on management of the clini­cally inapparent adrenal mass (“incidentaloma”) NIH Consens State Sci Statements. 2002;19(2):1-25.

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Published

2023-04-26

How to Cite

Kumar M., A., Roy, N., Jafri, H., Popli, V., Karthik, V. S., & Phuntsho, T. (2023). A RARE TUMOR – ADRENAL ANGIOSARCOMA: (case report). International Journal of Medicine and Medical Research, 8(2), 34–37. https://doi.org/10.11603/ijmmr.2413-6077.2022.2.13221