EFFECTS OF HEMOTOXIC SNAKE BITE ENVENOMATION ON HAEMATOLOGICAL PARAMETERS VARIABILITY IN PREDICTING COMPLICATIONS

Authors

DOI:

https://doi.org/10.11603/ijmmr.2413-6077.2020.2.11509

Keywords:

hemotoxic snake bite, acute kidney injury, shock, clotting time, bleeding time

Abstract

Background. Snake bite envenomation is a major public health problem in India with a high mortality rate. The major complications following a hemotoxic snake bite are disseminated intravascular coagulation (DIC), shock, acute kidney injury (AKI), acute respiratory distress syndrome (ARDS) and coagulopathy. The study explores a possible correlation of the haematological parameters studied to complications like DIC, AKI, acute renal failure (ARF), ARDS, shock and gastrointestinal (GI) bleed.

Objective. The aim of the study was to find out the effect of snakebite envenomation on the major haematological parameters of the body in relation to complications.

Methods. This cross-sectional study was conducted during a period of 18 months. 150 patients were included in the study after obtaining their informed consents. Data collection was done using a proforma. The study also compared clotting time (CT) by capillary tube method and whole blood clotting time at 20 minutes (WBCT20). SPSS software was used for statistical analysis.

Results. Among the people with complications, the majority (52%) of participants had AKI, 26% of them requiring dialysis, 16.7% participants had GI bleed, 11.3% participants had shock and 10% participants had DIC.

Conclusions. A prolonged bleeding time was found to be one of the most helpful haematological parameters in predicting shock and AKI. Clotting time by both capillary tube and WBCT20 methods were comparable in predicting complications.

Objective: The objective of this study was to find the effect of snakebite envenomation on the major haematological parameters of the body.

Material and method: This cross-sectional study was conducted over a period of 18months. A total of 150 patients were included in the study after obtaining informed consent. Data collection was done using a proforma. SPSS software was used for statistical analysis.

Results: Among the people with complications, the majority (52%) of participants had AKI, followed by 26% participants who required Dialysis, 16.7% participants had GI bleed, 11.3% participants had the shock and 10% participants had DIC.

Conclusion: A prolonged bleeding time was found to be one of the most helpful haematological parameters in predicting the shock and AKI.

Author Biographies

M. P. Harikrishnan, JUBILEE MISSION MEDICAL COLLEGE AND RESEARCH INSTITUTE, THRISSUR, INDIA

Senior Resident, MD General Medicine, Department of Medicine, Jubilee Mission Medical College and Research Institute, Thrissur

C. R. Anil Kumar, JUBILEE MISSION MEDICAL COLLEGE AND RESEARCH INSTITUTE, THRISSUR, INDIA

MD General Medicine, Associate Professor, Department of Medicine, Jubilee Mission Medical College and Research Institute, Thrissur

M. K. Anand, JUBILEE MISSION MEDICAL COLLEGE AND RESEARCH INSTITUTE, THRISSUR, INDIA

MD General Medicine, Assistant Professor, Department of Medicine, Jubilee Mission Medical College and Research Institute, Thrissur

J. Earali, JUBILEE MISSION MEDICAL COLLEGE AND RESEARCH INSTITUTE, THRISSUR, INDIA

MD General Medicine, Professor, Department of Medicine, Jubilee Mission Medical College and Research Institute, Thrissur

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Published

2021-05-18

How to Cite

Harikrishnan, M. P., Anil Kumar, C. R., Anand, M. K., & Earali, J. (2021). EFFECTS OF HEMOTOXIC SNAKE BITE ENVENOMATION ON HAEMATOLOGICAL PARAMETERS VARIABILITY IN PREDICTING COMPLICATIONS. International Journal of Medicine and Medical Research, 6(2), 22–29. https://doi.org/10.11603/ijmmr.2413-6077.2020.2.11509

Issue

Vol. 6 No. 2 (2020): International Journal of Medicine and Medical Research

Section

Internal Medicine

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