THE REAL HORIZONS OF PERSONALIZED MEDICINE. STRATEGY AND DEVELOPMENT OPTIONS
DOI:
https://doi.org/10.11603/mie.1996-1960.2016.4.7054Keywords:
personalized medicine, medicine mobile, patient-oriented medicine, transdisciplinarity, genomic and proteomic diagnostics, genomic passport rights, predictive medicine, individual health, characteristic symptoms, stable states in the disease development.Abstract
It's discussed the immediate and long-term prospects of personalized medicine. It is emphasized that the greatest results can be expected at the present time from a patient-oriented approach in the diagnosis, prognosis and the choice of the treatment modality, state monitoring and risk assessment. Particular attention has been paid to the possibility of considering the development of pathology as a wave process with trends that are possible to determine (calculate). It's proposed a generalized representation of the concept and quantitative analysis of symptoms trends.
References
Апанасенко Г. Биологическая деградация HOMO SAPIENS: пути противодействия. Основы. Концепции. Методы / Г. Апанасенко, В. Гаврилюк - Saarbrücken : Palmarium Academic Publishing, 2014. - 96 с.
Доклад о состоянии здравоохранения в Европе 2015 г. Целевые ориентиры и более широкая перспектива - новые рубежи в работе с фактическими даннями [Электронный ресурс] / Европейское региональное бюро ВОЗ. - 2015. - Режим доступу: http://www.euro. who.int/ru/data-and-evidence/european-health-report2015.
Персонализированная медицина: современное состояние и перспективы / И. И. Дедов, А. Н. Тюль-паков, В. П. Чехонин [и др.] // Вестник РАМН. - 2012. -№12.-С. 4-10.
Berg J. S. Deploying whole genome sequencing in clinical practice and public health: Meeting the challenge one bin at a time / J. S. Berg, M. J. Khouiy, J. P. Evans // Genetics in Medicine. - 2011. - Vol. 13, No. 6. - P. 499-504.
Chan I. S. Personalized medicine: progress and promise / I. S. Chan, G. S. Ginsburg //Annu. Rev. Genomics Hum. Genet. - 2011. - Vol. 12. - P. 217-244.
Garrison Jr. L. P. The economics of personalized medicine: a model of incentives for value creation and capture / L. P. Garrison Jr., M. J. Austin // Drug Information Journal. - 2007. - Vol. 41. - P. 501-509.
Hamburg M. A. The path to personalized medicine / M. A. Hamburg, F. S. Collins // N. Engl. J. Med. - 2010. -Vol. 363, No. 4. - P. 301-304.
Hoggatt J. Personalized medicine trends in molecular diagnostics: exponential growth expected in the next ten years / J. Hoggatt // Mol. Diagn. Ther. - 2011. - Vol. 15, No. l.-P. 53-55.
Jain К. K. From molecular diagnostics to personalized medicine / К. K. Jain // Exp. Rev. Mol. Diagn. - 2002. - Vol. 2, No. 4.-P. 299-301.
Jain К. K. Nanobiotechnology and personalized medicine / К. K. Jain // Prog. Mol. Biol. Transl. Sei. - 2011. - Vol. 104. - P. 325-354.
Nebert D. W. Personalize medicine: temper expectations / D. W. Nebert, G. Zhang // Science. - 2012. - Vol. 337, No. 6097.-P. 910.
Nishiyama M. Personalized medicine and molecular targets of drugs / M. Nishiyama // Nihon Rinsho. - 2010. -Vol. 68, No. 10. - P. 1917-1922.
Mirnezami R. Preparing for precision medicine / R. Mirnezami, J. Nicholson, A. Darzi // N. Engl. J. Med. -2012. - Vol. 366, No. 6. - P. 489-491.
Molecular medicine: a path towards a personalized medicine / D. M. Miranda, M. Mamede, B. R. Souza [et al.] // Rev. Bras. Psiquiatr. - 2012. - Vol. 34, No. 1. - P. 82-91.
Pollack A. Drug companies pursue personalized medicine approach [Electronic resource] / A. Pollack // New York Times. - 2010. - (November 16). - Retrieved from https ://prescriptions .blogs .nytimes. com/2010/ll/16/ drug-companies-pursue-personalized-medicine-approach/.
ScudellariM. Genomics contest underscores challenges of personalized medicine / M. Scudellari // Nat. Med. -2012.-Vol. 18, No. 3,-P. 326.
Spear В. B. Clinical application of pharmacogenetics / В. B. Spear, M. Heath-Chiozzi, J. Huff // Trends Mol. Med. - 2001. - Vol. 7, No. 5. - P. 201-204.
Downloads
Published
How to Cite
Issue
Section
License
Journal Medical Informatics and Engineering allows the author(s) to hold the copyright without registration
The majority of Medical Informatics and Engineering Open Access journals publish open access articles under the terms of the Creative Commons Attribution (CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited. The remaining journals offer a choice of licenses.
This journal is available through Creative Commons (CC) License CC-BY 4.0
