Medical Informatics and Engineering <p><em>Scientific-practical journal&nbsp;“Medical Informatics and Engineering”&nbsp;dedicated to the problems of implementing of IT-technology in medical science and practice.&nbsp;The main aim of the journal is to inform the porfessionals of health care industry of Ukraine, scientists, teachers of medical higher educational institutions, employees of medical and biological research institutes and the public about the results of fundamental and applied studies on Medical Informatics and Engineering,</em><em>about current trends and informatization processes occurring in the medical field.</em><br> <em><strong><span lang="EN-GB">ISSN 1997-7468 (Online), ISSN 1996-1960 (Print)</span></strong></em></p> Ternopil State Medical University en-US Medical Informatics and Engineering 1996-1960 <h3>Journal Medical Informatics and Engineering &nbsp;allows the author(s) to hold the copyright without registration</h3> <p>Users can use, reuse and build upon the material published in the journal but only for non-commercial purposes</p> <p>&nbsp;</p> <p>The majority of Medical Informatics and Engineering Open Access journals publish open access articles under the terms of the&nbsp;<a href="" target="_blank" rel="noopener">Creative Commons Attribution</a>&nbsp;(CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited. The remaining journals offer a choice of licenses.</p> <p>&nbsp;<img src="" alt="Результат пошуку зображень за запитом &quot;CC-BY logo&quot;"></p> <p><a href="" target="_blank" rel="noopener">This journal is available through&nbsp;Creative Commons (CC) License&nbsp; CC-BY 4.0</a></p> ABOUT THE PARADIGM OF COMBINING SYSTEMIC BIOLOGY AND SYSTEMIC MEDICINE REPRESENTATIONS FOR FORMING A NEW LOOK AT DIAGNOSTICS AND TREATMENT OF ISCHEMIC HEART DISEASE The possibilities of creating an intellectual bridge between the data of systemic biology and systemic medicine are explored. It is shown that creation of imitation models in silico are required to determine the role of trigger reactions, trigger cascades in the appearance of pathology. It is necessary to structure the accumulated medical knowledge, build ontological models of knowledge of different levels. O. P. Mintser L. Yu. Babintseva N. V. Kharchenko ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8886 STUDY OF CLASSIFICATION OF IMMUNOSENSORS FROM VIEWPOINT OF MEDICAL TASKS <p>Immunosensors and immunotests are commonly used in medicine, where blood, urine or saliva samples enable concentrations of morphine, progesterone, estradiol, dopamine, insulin to be determined.</p><p>In this work, the use of immunosensors for the following medical problems is considered: for the quantitative detection of alpha-fetoprotein, for determination of p53 protein in urine for diagnostics bladder cancer, for amperometric determination of carcinoembryonic antigen, for the determination of galectin-3, as biomarker of heart failure, for detecting hepatitis B surface antigen, for sensitive detection of tumor marker for determination of serum level in breast cancer patients.</p> V. P. Martseniuk A. Klos-Witkowska A. S. Sverstiuk ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8887 THEORETICAL AND METHODICAL, AND PRACTICAL FRAMEWORK FOR THE DEVELOPMENT AND IMPLEMENTATION OF SPECIALIZED COMPONENTS OF THE MEDICAL ELECTRONIC PASSPORT OF THE PERSON The expediency and the possibility of creation of specialized passports of a person are considered. It is proposed bioenergy component of the medical electronic passport, which can be widely used in preventive and medical institutions of various profiles, at enterprises, at sports and other institutions, with an automated assessment of the functional status of individuals, as well as in statistical studies and the identification of different social genotypic populations by their physical, intellectual and professional abilities. The nine most effective indicators of power supply of muscular activity of the person were revealed, a five-point system of estimation of their parameters was developed and five bioenergetic groups were identified, which include people with significantly different individual levels of energy supply of the organism. V. P. Karlenko O. P. Mintser O. V. Sarkanych B. V. Karlenko ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8888 WORKPLACE OF A PEDIATRICIAN The article describes the computer software complex of automated maintenance of the primary medical accounting documentation «Medical Registrar», which was developed to optimize the work of a pediatrician and pediatric nurse, who keeps accounting documentation. V. Z. Stetsyuk T. P. Ivanova I. P. Muha L. Yu. Babintseva N. V. Olhovych Yu. M. Chyzh ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8889 INFORMATION TECHNOLOGIES FOR EVALUATION OF SEVERITY AND MONITORING OF CHILDREN'S STATE WITH JUVENILE RHEUMATOID ARTHRITIS Systematization of the relevant data of quantitative monitoring of the population of children with rare (orphan) diseases remains a difficult problem. When assessing the severity of the pathological condition and monitoring the response to therapy, the criteria and indices of activity of juvenile rheumatoid arthritis are introduced. Such tools are necessary for choosing therapeutic programs, forecasting the course of the disease, and assessing the risks to the patient. Determining the set of data elements for mathematical modeling tasks is the primary stage of this process. O. P. Mintser T. Yu. Dubinina ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8890 TRANSDISCIPLINARY REPORTING OF INFORMATION WITH INTERACTIVE DOCUMENTS <p>Theoretical generalizations and possibilities of practical use of ontology of knowledge in public health, in particular in diagnosis and choice of a method of treatment for diseases of the gastrointestinal tract in children, are investigated. It is shown that the consequence of the existence of a homomorphism between the primary structure of the text and the structure of information from it highlights the possibility of constructing a specialized structure designed to work not with ontology objects but with lexemes of the primary structure. The interactive document (Tsn,NS') built on its basis can be used to form an arbitrary network information system in the object plane.</p> O. P. Mintser V. V. Pryhodnyuk O. Ye. Stryzhak O. M. Shevtsova ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8891 INFORMATION MODELS OF GENERAL NURSING CARE FOR PATIENTS WITH SUPPORT FOR DECISION ALGORITHMS BASED ON THE ICNP CLASSIFIER The paper presents information models of the nursing process through a conceptual presentation, including assessments of the patient's overall condition (nursing interviews, physical assessment, measurement, documentation analysis), nursing diagnosis, nursing care planning, determination of expected results, nursing manipulation, care plan implementation and care results evaluation. Particular attention is drawn to the possibility of using international terminology in describing nursing practices. Analysis of solutions is carried out using the terminology of decision trees. V. P. Matrtseniuk I. Ye. Andrushchak I. V. Tsikorska ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8892 ADVANTAGES OF ONLINE FORMS AS A MEANS OF TEACHING OF INTERNSHIP The article deals with the results of the analysis of the effectiveness of using online forms in the process of mastering the discipline «internal diseases». A pedagogical experiment was conducted with the inclusion of 46 interns who were engaged in the department during the period 2016-2017. It was found that the use of online forms to improve the efficiency of the educational process at the expense of, firstly, reducing the time spent on processing of the survey results, and, secondly, the optimization of the material assimilation level and «survival» knowledge of medical interns using a visual representation the results of the initial test and the substantive discussion on problematic issues. The combination of the online interviewing as a form of testing with the traditional way of control, and with self-control, can lead to a real system of objective assessment of the knowledge and realization of the main task of the educational process — the formation of strong knowledge and provide high-quality training of future specialists. V. I. Krivenko I. S. Kachan I. V. Nepryadkina O. P. Fedorova M. Yu. Kolesnik S. P. Pakhomova T. Yu. Radomskaya ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8893 PERSPECTIVES OF APPLYING NEW APPROACHES TO THE IMPLEMENTATION OF MATHEMATICAL TECHNOLOGIES IN THE STUDY OF CELL ACTIVITY <p>Photographs of ultrathin sections of the studied tissues are subject to the research. According to the method of determining the profiles of specific capabilities of hormonopoietic cells, based on cytophysiology data on the functional values of individual organelles and using elements of the cluster analysis, organelles are divided into separate groups (clusters) in accordance with their specialization in the cell. While applying the method of semi-quantitative analysis of electronograms, the structure and condition of the constituent elements of each cluster are compared with those in analogous ultrastructures both in the normal range and in the studied deviations. While applying the method of semi-quantitative analysis of electronograms, grading scale performs a digital evaluation of the characteristics' severity of each cluster element. The averaged results of the cluster elements evaluation serve as the basis for establishing certain interdependencies between them, which are objectified by correlation analysis with the construction of intra-cluster (intra-system) correlation portraits. For instance, a comparative study of the synthetic capacity of follicular thyrocytes in the thyroid gland of rats is presented through the commonly used linguistic description and analysis of the constructed correlation portrait.</p><p>Suggested approach to the study of a hormonopoietic cell not only makes it possible to establish interconnections between organelles within a certain cluster and to note the peculiarities of the implementation of a certain activity direction, but also allows to search for potential and reserve capabilities of the cell, which, in its turn, significantly broadens the very idea of its functional capabilities as the basis of life of any biological object.</p> O. I. Ryabukha ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8894 TECHNOLOGY OF «ADDITIONAL REALITY» IN SPECIALIZED MEDICAL EDITIONS <p>Printed publications are a separate direction for using the technology of augmented reality.</p><p>In the press, these technologies have found their place in presenting relevant news from the scene, interviews, in advertising technologies and the like. However, today no medical journal in the world uses the augmented reality, and only the editions of the Shupyk National Medical Academy of Postgraduate Education and NAMS of Ukraine for the first time start the program of applying augmented reality for their materials.</p> V. Savchenko ##submission.copyrightStatement## 2018-06-05 2018-06-05 1 10.11603/mie.1996-1960.2018.1.8895