Порушення в гемостазі у хворих на гострий панкреатит і шляхи корекції
DOI:
https://doi.org/10.11603/mcch.2410-681X.2015.v17.i2.4880Анотація
В огляді літератури наведено експериментальні та клінічні дані про зміни в системі гемостазу при
гострому панкреатиті. Розглянуто причини гемостазіологічних порушень, визначено можливі шляхи
корекції. Порушення в коагуляції є характерною ознакою при гострому панкреатиті й пов’язані з тяжкістю
захворювання. Результати експериментальних досліджень на тваринах і клінічні дані підтверджують, що
модуляція гемостазу може забезпечити терапевтичну мішень для лікування цієї патології. Пригнічення
каскаду згортання може запобігти внутрішньосудинному згортанню крові й запаленню в підшлунковій
залозі та віддалених органах, тим самим попереджуючи системні ускладнення у хворих на гострий пан-
креатит.
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