Changes of lipid peroxidation and antioxidant protection in spontaneously hypertensive rats during experimental treatment by Ramipril and Candesartan

Authors

  • A. V. Marushchak
  • Ye. I. Shorikov
  • D. V. Shorikova
  • I. R. Tymofiychuk
  • V. S. Haydychuk

DOI:

https://doi.org/10.11603/mcch.2410-681X.2016.v0.i1.6183

Abstract

This article talks about an investigation of the state of antioxidant-oxidation system for spontaneously hypertensive rats (SHR) using angiotensin-converting enzyme (ACE) drugs of short-term action. The study found that there is an increase of peroxidation processes while reducing the activity of antioxidant enzymes in the rats (SHR ), and there are features of regional influence of drugs above the level of lipid peroxidation and activity of antioxidant enzymes.

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Published

2016-05-12

How to Cite

Marushchak, A. V., Shorikov, Y. I., Shorikova, D. V., Tymofiychuk, I. R., & Haydychuk, V. S. (2016). Changes of lipid peroxidation and antioxidant protection in spontaneously hypertensive rats during experimental treatment by Ramipril and Candesartan. Medical and Clinical Chemistry, (1), 51–55. https://doi.org/10.11603/mcch.2410-681X.2016.v0.i1.6183

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Section

ORIGINAL INVESTIGATIONS