FASTING AND DIETARY THERAPY AS A TOOL FOR BIOCHEMICAL REGULATION OF THE BODY: PREVENTIVE, CLINICAL AND ANTI-AGING EFFECTS
DOI:
https://doi.org/10.11603/mcch.2410-681X.2025.i4.15929Keywords:
fasting and dietary therapy; therapeutic fasting; metabolic detoxification; autophagy; anti-aging; restoration of homeostasis; metabolism.Abstract
Introduction. The article presents a scientific and practical analysis of fasting and dietary therapy as a component of modern preventive, therapeutic and anti-aging approaches in medicine. The Aim of the Study. The purpose of the study is to systematize data on the effectiveness of the RDT method, show the mechanisms of action, application methods and clinical results in patients of various profiles. Research Methods. The work is an analytical review of modern scientific sources devoted to the study of biochemical, clinical and anti-aging effects of fasting and dietary therapy. The information base of the study was publications in the scientific databases PubMed, Scopus, Web of Science, Google Scholar, as well as in domestic professional medical publications. Results and Discussion. The mechanisms of the influence of temporary food restriction on metabolic processes, detoxification systems, cell regeneration and epigenetic changes that underlie the slowing down of aging processes are considered. Clinical observations and results of scientific studies are summarized, confirming the effectiveness of the method in many pathologies of internal organs and systems. The significance of fasting-dietary therapy as a method that causes systemic metabolic adaptation, accompanied by optimization of energy metabolism, reduction of anabolic load and activation of intracellular recovery mechanisms is outlined. These changes are associated with a decrease in metabolic and oxidative stress, normalization of lipid and carbohydrate metabolism and the formation of long-term preventive, therapeutic and anti-aging effects. Conclusions. Fasting and dietary therapy is a natural and effective way to stimulate the body’s endogenous recovery, which has not only a clinical but also a deep metabolic basis, which is confirmed by modern biochemical and biological research.
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