INVESTIGATION OF FLAVONOIDS IN THE EXTRACTS FROM CENTAURIUM ERYTHRAEA RAFN. HERB
DOI:
https://doi.org/10.11603/mcch.2410-681X.2024.i3.14931Keywords:
сommon centaury, Centaurium erythraea Rafn, flavonoids, spectrophotometryAbstract
Introduction. Common centaury (Centaurium erythraea) is a one- or two-year-old herbaceous plant of the Gentianaceae family, the genus Centaurium, which includes approximately 28 species growing throughout Europe. Numerous phytochemical studies have shown that C. erythraea contains a number of biologically active substances: secoiridoids, xanthones, terpenoids, flavonoids, phenolic and fatty acids, polysaccharides, and amino acids. This species is traditionally used in many countries around the world to treat a number of diseases of the cardiovascular system, gastrointestinal tract, kidneys, atopic dermatitis, asthma and pneumonia. It has been established that common centaury has antioxidant and antidiabetic activity.
The aim of the study – to determine the quantitative content of total flavonoids in extracts from the herb of common centaury using spectrophotometric method.
Research Methods. The objects for research were extracts from the grass of centaury, which were obtained by maceration and remaceration. The quantitative content of the total flavonoids was determined by the spectrophotometric method, using a Schimadzu 1800-UV spectrophotometer (Japan), in terms of rutin.
Results and Discussion. The results of the study showed that the content of the total flavonoids in the extract obtained from the grass of common centaury by the method of recessive maceration was 10120 μg/ml. The total quantitative content of the sum of flavonoids in the extract obtained by the maceration method from the studied raw materials was 11250 µg/ml. As a result of the study, it was found that the quantitative content of the sum of flavonoids in the extract obtained by maceration from the grass of common centaury was 1.11 times higher than in the extract obtained by remaceration.
Conclusions. The quantitative content of the sum of flavonoids in the extracts from the herb of common centaury obtained by maceration and remaceration was determined. It was found that the maceration method extracts slightly more flavonoids, their quantitative content is 11250 μg/ml. In the extract obtained by the remaceration method, the content of the total flavonoids was 10120 µg/ml. The obtained research results can be the basis for further phytochemical, pharmacological, microbiological studies and can be used in the development of medicines or dietary supplements based on common centaury.
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