INVESTIGATION OF PHENOLIC COMPOUNDS IN THE RAW MATERIALS OF ANGELICA ARCHANGELICA L.
DOI:
https://doi.org/10.11603/mcch.2410-681X.2023.i4.14378Keywords:
Angelica archangelica L., polyphenols, flavonoids, spectrophotometryAbstract
Introduction. Angelica archangelica L. are the most common species in the genus of Angelica L. in Ukraine. They grow on wetlands and waterfronts. Angelica archangelica L. has wide range of biological activity namely anti-inflammatory, antispasmodic, diuretic, antimutagenic, diaphoretic, sedative, cytotoxic, and anxiolytic properties, increases bile secretion, secretion of gastric and pancreatic juice, enhances intestinal motor function, inhibits fermentation. The root is used for bronchitis, gastric ulcers, anorexia, chronic fatigue, and migraine. Considering the fact that Angelica archangelica L. has not been studied so far, its phytochemical research is relevant.
The aim of the study – to determine the quantitative content of the amount of flavonoids and the amount of polyphenols in the raw material of the studied plant.
Research Methods. The research material was the leaves, rhizomes and roots of Angelica archangelica L., which were harvested in the territory of the Ternopil region. The quantitative content of the amount of polyphenols and the amount of flavonoids was determined by the spectrophotometric method, using a Lambda 25 UV spectrophotometer (Perkin Elmer, USA).
Results and Discussion. The research results showed that the content of the amount of polyphenols in the leaves and rhizomes and roots of Angelica archangelica L. was 4.19 % and 2.6 %. The total quantitative content of the amount of flavonoids in the leaves of the studied plant was 4.74 %, and in the rhizomes and roots – 0.34 %. The research results showed that the quantitative content of the amount of flavonoids in the leaves of angelica was almost 4 times higher than in the rhizomes and roots of the studied object.
Conclusions. The quantitative content of total polyphenols and total flavonoids in leaves and rhizomes and roots of Angelica archangelica L. was determined. It has been established that angelica leaves contain a significant amount of polyphenols and flavonoids – 4.19 % and 4.74 %, respectively. The obtained results indicate the prospects for further in-depth phytochemical studies of biologically active substances of Angelica archangelica L.
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