INFLUENCE OF THE FACTOR OF HEREDITY ON THE DEVELOPMENT OF PRIMARY ARTERIAL HYPERTENSION IN YOUNG AGE PATIENTS
DOI:
https://doi.org/10.11603/1811-2471.2018.v0.i2.8938Keywords:
primary arterial hypertension, young age, heredity, metabolic syndrome.Abstract
Recently the prevalence of essential hypertension (EH) in young patients has increased. At the same time, a relatively high percentage of these patients has the presence of certain components of the metabolic syndrome (MS).
The aim of our study – to determine the family inheritance of individual components of the MS and their impact on the development of hypertension in young patients.
It was examined 56 young patients, 26 female and 30 male with manifestations of essential hypertension. The average age of the surveyed patients was (23.5±2.4) years. We have been interviewing these patients for the purpose of identifying diseases – markers such as type 2 diabetes, abdominal obesity (AO), hypertension, atherosclerotic vascular disorders, including coronary heart disease (CHD), history of acute cerebrovascular accident (ACVA), and myocardial infarction (MI), gouty arthritis and asymptomatic hyperuricemia in the relatives. Each of these diseases gave 1 point, in the end the balls were added. After analyzing the data, we found that type 2 diabetes occurred in a family history of 21 patients (38 %), hypertension – in 41 patients (73 %), AO – in 20 patients (36 %), atherosclerotic vascular lesions – in 36 patients (64 %), GPMK and IM – in 21 patients (38 %), gouty arthritis and asymptomatic hyperuricaemia – in 10 patients (18 %). According to the correlation analysis, there was a correlation between the degree of severity of hypertension and the number of points scored on the questionnaires (r=0.769, p=0.326).
Conclusion. the role of heredity in the development of primary hypertension in young patients is significant. It is necessary to do further analysis of genetic factors that may influence the development of individual components of the MS in patients with hypertension in young adults.
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