ANALYSIS OF THE REHABILITATION PROGRAM ACTIVITY FOR PATIENTS WITH CHRONIC PANCREATITIS AND RELATED ANEMIA AT THE AMBULATORY LEVEL
DOI:
https://doi.org/10.11603/1811-2471.2018.v0.i2.8564Keywords:
chronic pancreatitis, iron-deficiency anemia, polydeficiency anemia, complex iron-containing polymineral-vitamin preparation.Abstract
Problem of polydefinitic anemia prevalence is very topical today. It is justified by the fact that the insufficiency of iron in the body is usually associated with deficiency of copper, zinc, cobalt, manganese, protein, vitamins B and C, whose role in the body is directly related to the exchange of iron. That is why, the use of a complex iron-containing polymineral-vitamin preparation was supplemented by 1 capsule twice a day for a month twice a year in addition to the general treatment scheme, as rehabilitation measures.
The aim – to conduct a comparative analysis of iron metabolism parameters in patients with CP in combination with IDA in the course of conventional treatment and therapy program using a complex iron-containing polymineral-vitamin preparation Fersinol-Z.
Materials and Methods. The treatment regimens of 29 examined patients with CP and concomitant anemia who were treated on the basis of the Gastroenterological Department of the Ternopil Clinical Town Hospital No. 2 were analyzed. The positive dynamics of the studied iron exchange rates after treatment was compared with those before treatment: the level of RBC increased by 14.28 %, HGB – by 12.36 %, KP – by 3.49 %, HCT by 26.69 %, MCV by 9.45 %, IS by 40.63 %, SOT by 55.10 %, IBAS and LIBAS decreased by 9.33 % and 19.11 % respectively (p<0.05). The levels of MCV and HCT were normalized, which testified complete elimination of red cell cytosis. The level of LIBAS also normalized, which testifyed the replenishment of the iron depot. Admission of the drug leds to a reduction of CP’s exacerbations, depending on the severity of the clinical course of CP: in patients with mild course – from (1.48±0.15) to (0.68±0.1), with an average degree of severity – from (2.32±0.17) to (1.87±0.19) and severe – from (4.11±0.31) to (3.18±0.37).
Conclusion. The inclusion in the program of complex rehabilitation of chronic pancreatitis with concomitant ZDA of complex iron-containing polymineral-vitamin preparation Fersinol-Z has led to an improvement of laboratory parameters of iron exchange, as well as to a decrease in the number of recurrences of СP, which proved the effectiveness of the proposed course of rehabilitation for influencing the clinical course of CP with concomitant anemia.
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