PARTICULARITIES OF THE MORPHOGENESIS OF RAT'S TONGUE UNDER CONDITIONS OF WATER-ELECTROLYTE DISBALANCE OF AN ORGANISM.
DOI:
https://doi.org/10.11603/1811-2471.2017.v1.i3.7956Keywords:
the mucous membrane of tongue, hypertonic dehydration, ultrastructure.Abstract
Abstract. The organism dehydration is one reason of the functional diseases of mucous membrane of oral cavity. The tongue changes study at the cellular and tissue levels under the influence of organism hypertonic dehydration provides obtaining the new knowledge for scientific justification of targeted prevention and drug therapy tongue diseases in humans and animals. The research goal was to study the morphological features of rat’s tongue under the influence of organism hypertonic dehydration. The experiment was performed on 20 white laboratory rats. The specimens were analyzed using the light microscope "OLYMPUS" (Japan), scanning and transmission electron microscope («SEM-125K» and «SEM-106A») (Sumy, Ukraine). It was found that the disruption of ordered cells distribution of epithelium of tongue mucous membrane occurs under influence of mild cellular dehydration. The epithelial cells of basal layer and stratum spinosum are decreased in size, their contacts are lost and the space between them is increased. The premature of the granulosa cells disruption and the edema of lamina propria are occurred. The epithelial thickness is increased by 3,86% (р = 0,0791) and the lamina propria thickness is increased by 6,46% (р = 0,2094). The bundles of myofibrils are locally become thin and are lost the parallel arrangement, and are get the wavy circuit due to the compression by swollen connective tissue interlayers. The width of endomysium and perimysium is increased by 5,37% (р = 0,6772) and 6,23% (р = 0,6057) accordingly. The microcirculatory bloodstream vessels were become plethoric, their walls were edematous and their lumens were enlarged.
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