INVESTIGATION OF STRUCTURAL CHANGES IN VENTRICLES OF COR PULMONLE BY POLARIZATION MICROSCOPY
DOI:
https://doi.org/10.11603/1811-2471.2016.v27.i3.6778Keywords:
cor pulmonale, ventricles, polarization microscopy.Abstract
SUMMARY. In experimental condition there was found that post-resection arterial pulmonary hypertension leads to the development of pulmonary heart and severe structural reconstruction left and right ventricles. The latter is characterized by hypertrophy of cardiomyocytes, their nuclei, dystrоphic and necrobiotic changes of cells and tissues, infitration and sclerotic processes. Polarization microscopy adequate reflect structural changes of myofibrillar structures in form contracture injures of cardiomyocytes, foci of myocytolyses, cracs and dissociation of cardiac muscle fibers, foci of granular-clumpy decay. Revealed morphological changes in the right ventricles dominated decompensatory pulmonary heart.
References
Amosova K. M. Klinichnyy perebih ta stan miokarda z khronichnym lehenevym sertsem unaslidok khronichnoyi obstruktyvnoyi patolohiyi lehenʹ zalezhno vid nayavnosti lehenevoyi hipertenziyi / K. M. Amosova, L. F. Konoplʹova, I. D. Mazur // Sertse i sudyny. – 2009. – № 2. – S. 48–52.
Konopleva L. F. Khronycheskoe lehochnoe serdtse: problemy klassyfykatsyy, dyahnostyky y lechenyya / L. F. Konopleva // Zdorov'ya Ukrayiny. – 2011. – № 1 (13). – S. 24–26.
Noreyko B. V. Khronycheskore lehochnoe serdtse / B. V. Noreyko, S. B. Noreyko // Novosty medytsyny y farmatsyy. – 2011. – № 9 (364). – S. 14–17.
Makarov M. A. Rolʹ dysfunktsyy éndotelyya y ryhydnosty arteryy v patoheneze khronycheskoy obstruktyvnoy bolezny lehkykh / M. A. Makarov, S. N. Avdeev, A. H. Chuchalyn // Terapevtycheskyy arkhyv. – 2012. – № 3. – S. 74–80.
Sadovnykov V. A. Modelyrovanye sostoyanyya dezyntehratsyy serdtsa predelʹnymy zahruzkamy / V. A. Sadovnykov, A. N. Baranov // Morfolohyya. – 1998. – T. 113, № 3. – S. 104–106.
Tatarchuk L. V. Morfometrychnyy analiz remodelʹovanykh kamer sertsya pislya pulʹmonektomiyi / L. V. Tatarchuk // Zdobutky klinichnoyi ta eksperymentalʹnoyi medytsyny. – 2011. – № 2 (15). – S. 123–126.
Avtandylov H. H. Osnovy kolychestvennoy patolohycheskoy anatomyy / H. H. Avtandylov. – M. : Medytsyna, 2002. – 268 s.
Horalʹsʹkyy L. P. Osnovy histolohichnoyi tekhniky i morfofunktsionalʹni metody doslidzhennya u normi ta pry patolohiyi / L. P. Horalʹsʹkyy, V. T. Khomych, O. I. Kononsʹkyy. – Zhytomyr : Polissya, 2011. – 288 s.
Barnes P. Y. Chronic obstructive pulmonary disease molecular and cellular mechanisms / P. Y. Barnes, D. Shapiro, R. A. Pamwels // Eur Respirat. J. – 2003. – Vol. 22. – P. 672–678.
Cowie M. Survival of patients with a new diagnosis of heart failure: a population based study / M. Covie, D. Wood, A. Coats // Heart. – 2000. – Vol. 83. – P. 505–510.
Simonnean G. Clinical classification of pulmonary hypertension / J. Simonnean, N. Galie, L. Rubin // Y. Am. Cell. Cardiol. – 2004. – № 12. – P. 55–125.