DYNAMICS OF BONE MINERAL DENSITY AND INDEX MINERALIZATION IN THE LATE PERIOD OF TRAUMATIC DISEASE AGAINST EXPERIMENTAL POSTMENOPAUSAL OSTEOPOROSIS
DOI:
https://doi.org/10.11603/1811-2471.2016.v27.i3.6772Keywords:
menopause, osteoporosis, injury.Abstract
Summary. Modeling of skeletal and cranio-skeletal injuries is accompanied by a significant breach of bone mineral density and bone mineralization index, which is significantly higher in 1 month of post-traumatic period in the animals with a combined cranio-skeletal injury. Modeling injuries in 30 days after the removal of the gonads leads to a significant reduction in the studied parameters after 1 month of post-traumatic period, remaining at the same level for 2 months of the experiment. In these experimental conditions, violations of bone mineral density and salinity index is significantly lower than in animals without hyoestrogenic osteoporosis, which is especially pronounced after 2 months of the experiment.
References
Avtandylov H. H. Osnovy kolychestvennoy patolohycheskoy anatomyy / H. H. Avtandylov. – M. : Medytsyna, 2002. – 240 s.
Berezovskaya O. P. Osteohenez v uslovyyakh hypokynezyy y hypoksyy / O. P. Berezovskaya, Y. H. Lytovka // Problemy ekolohichnoyi ta medychnoyi henetyky i klinichnoyi imunolohiyi. Zbirnyk naukovykh pratsʹ. – Kyyiv; Luhansʹk; Kharkiv, 2002. – Vyp. 6 (45). – S. 19–31.
Elʹskyy V. N. Modelyrovanye cherepno-moz·hovoy travmy / V. N. Elʹskyy, S. V. Zyablytsev. – Donetsk: Yzd-vo “Novyy myr”, 2008. – 140 s.
Zakhurdaeva L. D. Éstroheny: byolohycheskye y farmakolohycheskye éffekty / L. D. Zakhurdaeva // Med. aspekty zdorovʹya zhenshchyny. – 2010. – № 8. – S. 41–45.
Kamyshnykov V. S. Klynyko-laboratornyy monytorynh byokhymycheskykh markerov osteoporoza v éksperymente / V. S. Kamyshnykov, YU. D. Kovalenko, N N. Kokhnovych // Dostyzhenyya medytsynskoy nauky Belarusy. – 2003. – http://med.by/dmn/book.php?book=03-18_10.
Levytsʹkyy A. P. Vykorystannya preparatu Osteovitu dlya profilaktyky hlyukokortykoyidnoho osteoporozu / A. P. Levytsʹkyy, O. A. Makarenko // Endokrynolohiya. – 2008. – T. 13, № 1. – C. 92–97.
Malysh Y. R. Profylʹ tsytokynov v dynamyke posttravmatycheskoho peryoda u postradavshykh s tyazheloy polytravmoy / Malysh Y. R., Kozlov V. K., Z·hrzheblovskaya L. V. // Ukrayinsʹkyy zhurnal ekstremalʹnoyi medytsyny imeni H. O. Mozhayeva. – 2005. – T. 6, № 3. –
S. 66–78.
Naukovo-praktychni rekomendatsiyi z utrymannya laboratornykh tvaryn ta roboty z nymy / YU. M. Kozhemʺyakin, O. S. Khromov, M. A. Filonenko, H. A. Sayfetdinova – Kyyiv : Avitsena, 2002. – 156 s.
Povoroznyuk V. V. Ymmunolohycheskye aspekty postmenopauzalʹnoho osteoporoza / V. V. Povoroznyuk, N. A. Reznychenko, É. A. Maylyan // Bolʹ. Sustavy. Pozvonochnyk. – 2013. – № 3. – S. 21–26.
Povoroznyuk V. V. Rehulyatsyya éstrohenamy remodelyrovanyya kostnoy tkany / V. V. Povoroznyuk, N. A. Reznychenko, É. A. Maylyan // Reproduktyvnaya éndokrynolohyya. – 2014. – № 1. – S. 14–18.
Roshchin H. H. Bahatofaktornyy analiz letalʹnosti pry poyednaniy travmi orhaniv cherevnoyi porozhnyny / H. H. Roshchin, V. I. Ivanov, V. O. Krylyuk // Klinichna khirurhiya. – 2013. – № 4. – S. 40–44.
Chernov YU. N. Osteoporoz: krytycheskye zvenʹya patoheneza y puty farmakolohycheskoy korrektsyy / YU. N. Chernov, L. K. Peshekhonova // V myre lekarstv. – 2000. – № 2. – S. 44–50.