IMPACT OF «CITOFLAVIN» ON BIOELECTRICAL ACTIVITY OF THE NEUROMUSCULAR COMPLEX IN CONDITION OF EXPERIMENTAL MENOPAUSE
DOI:
https://doi.org/10.11603/1811-2471.2016.v26.i2.6250Abstract
SUMMARY. The aim – experimental study of changes in bioelectric activity of the neuromuscular complex under
the influence of the drug «Citoflavin» under experimental menopause. The drug was administered intraperitoneally to
female white rats after 120 days ovariohysteroectoy for 10 days. There were analyzed the parameters of neuromuscular
excitability complex parameters and responses caused by direct and indirect stimulation of the gastrocnemius muscle.
There was significant (p<0.01) increase in arousal threshold gastrocnemius muscle as the direct and indirect stimulation
to 120.0 7.27 % and 85.71±6.15 % respectively. Also, it was marked the decrease of the relative low threshold neuromotor
units. Thus, under the influence of the drug Citoflavin, a normalization of excitability of the neuromuscular system under
test and the drug can be recommended for use as a component of comprehensive treatment and prevention remote
neuropathic complications of early menopause.
KEY WORDS: surgical menopause, neuromuscular complex, Citoflavin.
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