DYNAMICS OF ENDOGENOUS INTOXICATION INDICATORS DURING THE LATE MANIFESTATIONS OF TRAUMATIC DISEASE AFTER CRANIO-SKELETAL INJURY AND EFFECTIVENESS OF ITS CORRECTION BY PHYTOMIXTURE
DOI:
https://doi.org/10.11603/1811-2471.2016.v25.i1.6020Abstract
SUMMARY. In terms of modeling cranio-skeletal injuries during the late traumatic disease manifestations a
significant increase in the level of endogenous intoxication was observed. It was manifested by increase of erythrocyte
index value intoxication (EI) and content fractions average molecular weight (MSM) in the blood serum. The level of EI was
significantly greater than controls in all periods of observation with a moderate decline after 35 days. The characteristic
feature of the dynamics of content MSM serum fractions is their high level after 14 days with normalization after 28 days
and re-growth after 35 days. After applying phytomixture a significant decrease in endotoxemia was observed. Value of
EI reaches the level of control after 35 days, and fractions MSM - starting from 28 days.
KEY WORDS: cranio-skeletal injury, endogenous intoxication, phytotherapy, phytomixture.
References
Rannyaya dyahnostyka syndroma polyorhannoy
dysfunktsyy u postradavshykh s polytravmoy / S. V. Hay-
duk, V. V. Boyaryntsev, S. V. Havrylyn [y dr.] // Polytrav-
ma: dyahnostyka, lechenye y profylaktyka oslozhne-
nyy : materyaly II Vserossyyskoy nauchno-praktycheskoy
konferentsyy. – Lenynsk-Kuznetskyy, 2007. – S. 40.
Yzbrannye aspekty patoheneza y lechenyya trav-
matycheskoy bolezny / V. N. Elʹskyy, V. H. Klymovytskyy,
S. E. Zolotukhyn [y dr.] – Donetsk : OOO «Lebedʹ», 2002. –
s.
Éndotoksykoz pry tyazheloy sochetannoy travme /
Y. A. Eryukhyn, S. V. Havrylyn, N. S. Nemchenko [y dr.] //
Vestn. khyrurhyy. – 2001. – T. 160, № 5. – S. 120–124.
Osobennosty yzmenenyy aktyvnosty oksyreduk-
taz, soderzhanyya malonovoho dyalʹdehyda y molekul
sredney massy v krovy bolʹnykh s cherepno-moz·hovoy
travmoy razlychnoy stepeny tyazhesty / D. E. Yvanov,
D. M. Puchynʹyan, V. H. Nynelʹ [y dr.] // Klyn. lab. dyahnostyka.
– 2001. – № 5. – S. 40–41.
Karyakyna E. V. Molekuly sredney massy kak yn-
tehralʹnyy pokazatelʹ metabolycheskykh narushenyy :
obzor lyt. / E. V. Karyakyna, S. V. Belova // Klyn. lab.
dyahnostyka. – 2004. – № 3. – S. 3–7.
Kozak D. V. Dynamika pokaznykiv endohennoyi in-
toksykatsiyi v umovakh politravmy / D. V. Kozak // Zdobut-
ky klinichnoyi ta eksperymentalʹnoyi medytsyny. – 2012. –
№ 1 (16). – S. 69–71.
Metody doslidzhennya endohennoyi intoksykatsiyi
orhanizmu : metodychni rekomendatsiyi / M. A. Andrey-
chyn, M. D. Bekh, V. V. Demʺyanenko [ta in.]. – K., 1998. –
S. 10–13.
Servatovych A. M. Dynamika porushenʹ pro-
tsesiv lipidnoyi peroksydatsiyi v period piznikh proyaviv
travmatychnoyi khvoroby pislya kranioskeletnoyi travmy
ta efektyvnistʹ yiyi korektsiyi fitozborom / A. M. Serva-
tovych // Visnyk
naukovykh doslidzhenʹ. – 2015. – № 4. –
S. 106–109.
Sposob dyahnostyky éndohennoy yntoksykatsyy /
A. A. Tohaybaev, A. V. Kurhuzkyn, R. M. Rykun, R. M. Kryb-
zhanova // Lab. delo. – 1988. – T 4, № 9. – S. 22–24.
Sur S. Problemy ta perspektyvy rozrobky i
vprovadzhennya suchasnykh likarsʹkykh zasobiv roslynno-
ho pokhodzhennya / S. Sur, O. Hrytsenko // Liky Ukrayiny. –
– № 4. – S. 47–49.
Servatovych A. M. The role of antioxidant defense
disturbances in pathogenesis of the late manifestations
of traumatic disease after cranio-skeletal injury and effectiveness
of its correction by phytomixture / A. M. Servatovych,
A. A. Gudyma // Journal of Education, Health
and Sport. – 2015. – Vol. 5, № 12. – P. 271–278 – [Rezhym
dostupu] http:ojs.ukw.edu.pl/index.php/johs/article/view/
%3B5(12)%3A271-278.
Valnet J. Phytoterapie: traitement de maladies
par les plantes / J. Valnet. – Paris : Maloine, 1983. – 942 p.
