CLINICAL FEATURES OF THE COURSE OF HEART FAILURE IN PATIENTS WITH ISCHEMIC DISEASE IN COMBINATION WITH HYPERTENSIVE DISEASE AFTER CORONAVIRUS INFECTION (COVID-19)
DOI:
https://doi.org/10.11603/1811-2471.2026.v.i1.15882Keywords:
heart failure, clinical course, cardiac arrhythmias, COVID-19Abstract
SUMMARY. The aim – to study the features of the clinical course of CHF in patients with ischemic heart disease in combination with hypertension after a previous coronavirus infection.
Material and Methods. The main study group consisted of 60 patients with ischemic heart disease (IHD) and hypertension (HT) who had contracted COVID-19, recovered and were discharged from the infectious disease department 8-12 months ago. Among them were 40 (66.7%) men and 20 (33.3%) women aged 45-65 years. Patients with IHD and HT (50 people) who did not have COVID-19 formed the comparison group. Among them were 33 (66.0%) men and 17 (34.0%) women (mean age – 55.9±5.6 years). The groups were statistically comparable in age (p=0.309 by t-test), gender (p=0.941 by c2) and duration of IHD: 6.7±1.8 years and 6.2±2.1 years, respectively (p=0.182 by t-test).
A general clinical examination was performed (collection of complaints, clinical assessment of retrosternal pain syndrome, anamnestic data with clarification of the duration of (IHD), electrocardiogram (ECG), one- and two-dimensional echocardiography (ECHO-CG) on the "Esaote.my lab class C" device using standard methods, laboratory examination.
Results. Clinical course of chronic heart failure (CHF) in patients with IHD combined with HT who have had COVID-19 is characterized by significantly more frequent events of angina attacks, episodes of ST-segment depression, cardiac rhythm and conduction disorders, compared with those in patients in the comparison group (p<0.001). Atrial fibrillation occurred in 13 (21.7%) patients in the main group versus 6 (12.0%) in patients in the comparison group. Life-threatening cardiac rhythm disorders were recorded in 32 (53.3%) patients in the main group versus 12 (24.0%) in patients.
Conclusions. The impact of a previous coronavirus infection in patients with IHD combined with HT leads to a more severe clinical course of CHF, compared with that in patients who did not have COVID-19, which is due to cardiac remodeling with an increase in the mass of the left ventricular (LV) myocardium, dilation of its cavities and a moderate decrease in the LV ejection fraction (48.6%).
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Accepted 2026-01-27
Published 2026-04-22
