RESEARCH ON VOLATILE COMPONENTS OF EUPATORIUM CANNABINUM L.

Authors

  • І. С. Дахим Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine https://orcid.org/0000-0003-3806-626X
  • S. M. Marchyshyn Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine https://orcid.org/0000-0001-9585-1251
  • L. V. Slobodyanyuk Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine https://orcid.org/0000-0002-0400-1305
  • O. L. Demydyak Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine https://orcid.org/0000-0003-0988-6058
  • O. I. Dzyoba Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1811-2471.2025.v.i1.15248

Keywords:

hemp agrimony, herb, volatile compounds, essential oils, GC/MS

Abstract

SUMMARY. The use of medicinal plants for medicinal purposes dates back to ancient times. As a result of the accumulated experience of past generations and the present, phytotherapy has found widespread use. It is known that 75 % of the world's population uses medicinal plants and herbal preparations based on them for the treatment and prevention of various ailments. Therefore, the study of new, unofficial medicinal plants, including the little-studied species from the Asteraceae family, hemp agrimony (Eupatorium cannabinum L.), is of theoretical and practical interest. It is used mainly in traditional medicine in different countries of the world as a choleretic, diuretic, blood-purifying, antibacterial, antifungal and anti-inflammatory agent.

The aim – to study the component composition and determine the quantitative content of volatile components of hemp agrimony herb.

Material and Methods. The raw material sample - hemp agrimony herb, was harvested in the summer of 2024 in Ternopil region. In order to study the component composition of volatile compounds of the hemp agrimony herb, the GC/MS method was used using a gas chromatograph of the 6890N/5973inert series manufactured by “Agilent Technologies” (USA).

Results. Gas chromatography-mass spectroscopy identified 34 compounds in the herb of hemp agrimony. Volatile compounds contained significant amounts of anisole (490.99 μg/g), germacrene D (433.16 μg/g), 4-carene (359.43 μg/g) and β-cymene (285.92 μg/g). The lowest content was found for α-terpineol and cis-muurol (8.01 μg/g and 14.28 μg/g), respectively.

Conclusions. The component composition of the E. cannabinum L. herb was studied by GC/MS. Such pharmacologically important components as anisole, germacrene D, 4-carene and β-cymene were detected in significant quantities, which indicates the prospects for further phytochemical and pharmacological studies of analyzed medicinal plant material with the aim of creating new herbal preparations.

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Published

2025-04-11

How to Cite

Дахим, І. С., Marchyshyn, S. M., Slobodyanyuk, L. V., Demydyak, O. L., & Dzyoba, O. I. (2025). RESEARCH ON VOLATILE COMPONENTS OF EUPATORIUM CANNABINUM L. Achievements of Clinical and Experimental Medicine, (1), 93–97. https://doi.org/10.11603/1811-2471.2025.v.i1.15248

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Original research articles