CLINICAL AND EPIDEMIOLOGICAL PICTURE OF COMORBID CHRONIC SALPINGO-OOPHORITIS AND TYPE 2 DIABETES MELLITUS IN WOMEN WITH INFERTILITY
DOI:
https://doi.org/10.11603/1811-2471.2025.v.i4.13906Keywords:
inflammatory diseases of the pelvic organs, diabetes mellitus, infertility, comorbidity, age, diseases of the urinary system, infectious profile, clinical pictureAbstract
SUMMARY. The aim – to analyze clinical and epidemiological data in the comorbidity of chronic salpingo-oophoritis and type 2 diabetes mellitus in women with infertility.
Material and Methods. The study analysed medical records and examined 53 infertile women of reproductive age with chronic salpingo-oophoritis (n=24), type 2 diabetes mellitus (n=11) and their combination (n=18), who were undergoing inpatient treatment at the Ternopil Municipal Hospital No. 2.
Results. It was found that patients with chronic salpingo-oophoritis (ChrSO) were significantly younger than women with type 2 diabetes mellitus (T2DM) (by 38.96 %) and women with ChrSO+T2DM (by 35.51 %). In the ChrSO group, the duration of infertility was significantly shorter. Also, unlike other groups, where only primary infertility was observed, patients with ChrSO had an equal distribution between primary and secondary infertility. The main etiological factor of ChrSO was tubal-peritoneal (70.83 %), while in women with T2DM and ChrSO +T2DM, a combined syndrome (polycystic ovary syndrome, male and tubal-peritoneal factors) dominated, which was detected in 81.82 % and 94.44 % of cases, respectively.
Patients with T2DM and ChrSO +T2DM were more likely to be diagnosed with urinary tract diseases, particularly cystitis (63.64 % and 83.3 %, respectively) and colpitis. In the infectious profile of the vagina in these groups, Ureaplasma urealyticum, parvum prevailed, while in the ChrSO group, Candida albicans and Escherichia coli were the most common. The structure of gynaecological pathology in the ChrSO group was dominated by cervical ectopia and follicular cysts, in the T2DM group – by endometrial hyperplasia and sexually transmitted infections (STIs), and in the ChrSO +T2DM group – by STIs and cervical ectopia.
In terms of clinical manifestations, all groups were characterised by asymptomatic course in 33–45 % of cases and menstrual cycle disorders (88–-100 %). However, patients with T2DM and ChrSO+T2DM more often experienced chronic pelvic pain, sexual dysfunction, and vaginal discharge.
Conclusions. The results of the study highlight significant differences in the clinical, anamnestic, and etiological characteristics of the comorbid course of ChrSO and T2DM in infertile women of reproductive age compared to patients with monopathologies.
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Accepted 2026-01-06
Published 2026-02-09
