CLINICAL AND EPIDEMIOLOGICAL PARALLELS OF HEART FAILURE AND ATRIAL FIBRILLATION
DOI:
https://doi.org/10.11603/1811-2471.2022.v.i2.13130Keywords:
atrial fibrillation, atrial fibrillationepidemiologyAbstract
SUMMARY. The aim – to assess the prevalence of HF in patients with AF.
Material and Methods. The study was performed on the basis of the regional clinical hospital (Odesa) in 2018–2021. Medical records of 2459 patients with HF were retrospectively studied. All patients were examined in accordance with the Unified Protocol of Medical Care, Order of the Ministry of Health of Ukraine No. 384 (2012). All patients were assessed for exercise tolerance using a 6-minute walk test. Statistical processing was performed by methods of analysis of variance and correlation.
Results. The average age of patients was 64.3–1.9 years, In 2.2 % of patients under the age of 60 was found AF, whereas amongst older patients there were 13.3 % cases. Ist FC CH was in 34 (65.4 %) patients, III FC CH – in 34.6 %. The average test score with a 6-minute walk was 277.5±12.5 m, the average time of restitution after exercise – 32.3±3.7 s. The average score on the CHADS-VASC scale was 4.2±0.3 points, HAS-BLED – 2.9±0.2 points. The results of 6-minutes walking test correlated with the duration of AF (r=-0.66).
Conclusions.1. There were 2.2 % of patients under the age of 60 had AF, in older patients – in 13.3 % of cases. The constant form of AF is the most often noted variant.
- Inverse correlation between the distance traveled by the patient in 6 minutes and the duration of AF (r=-0.66) was found.
References
Ariyaratnam, J.P., Lau, D.H., Sanders, P., & Kalman, J.M. (2021). Atrial Fibrillation and Heart Failure: Epidemiology, Pathophysiology, Prognosis, and Management. Card. Electrophysiol. Clin., 13(1), 47-62. DOI: 10.1016/j.ccep.2020. 11.004. PMID: 33516407.
Louka, A.M. Tsagkaris, C., & Stoica A. (2021). Clinical risk scores for the prediction of incident atrial fibrillation: a modernized review. Rom. J. Intern. Med., 59(4), 321-327. DOI: 10.2478/rjim-2021-0018. PMID: 33951355.
Werhahn, S.M., Becker, C., Mende, M., Haarmann, H., Nolte, K., Laufs, U., … Wachter, R. (2021). NT-proBNP as a marker for atrial fibrillation and heart failure in four observational outpatient trials. ESC Heart Fail, 30. DOI: 10.1002/ehf2.13703. Epub ahead of print. PMID: 34850596.
Carpenito, M., Fanti, D., Mega, S., Benfari, G., Bono, M.C., Rossi, A., Ribichini, F.L., & Grigioni, F. (2021). The Central Role of Left Atrium in Heart Failure. Front. Cardiovasc. Med., 8, 704-762. DOI: 10.3389/fcvm.2021.704762. PMID: 34485406; PMCID: PMC8414134.
Pool, L., Wijdeveld, L.F.J.M., de Groot, N.M.S., & Brundel, B.J.J.M. (2021). The Role of Mitochondrial Dysfunction in Atrial Fibrillation: Translation to Druggable Target and Biomarker Discovery. Int. J. Mol. Sci., 22(16), 8463. DOI: 10.3390/ijms22168463. PMID: 34445167; PMCID: PMC8395135.
Nakaz MOZ Ukrayiny vid 03.07.2006 № 436 Pro zatverdzhennya protokoliv nadannya medychnoyi dopomohy za spetsialnistyu „Kardiolohiya" – Order of the Ministry of Health of Ukraine dated 03.07.2006 No. 436 On the approval of protocols for the provision of medical care in the specialty "Cardiology". Retrieved from: http://www.moz.gov.ua/ua/portal/dn_20060703_436.html [in Ukrainian].
Diahnostyka i likuvannya khronichnoyi sertsevoyi nedostatnosti: Rekomendatsiyi Yevropeyskoho tovarystva kardiolohiv, 2016 r.: Elektronnyy resurs – Diagnosis and treatment of chronic heart failure: Recommendations of the European Society of Cardiology, 2016: Electronic resource. Retrieved from: http://health-ua.com/article/4772-dagnostika--lkuvannya-hronchno-sertcevo-nedostatnost--rekomendatc-vropejsko [in Ukrainian].
Orlov, V.N. (2017). Rukovodstvo po elektrokardiografii – Guide to Electrocardiography. Мoscow: MIA [in Russian].
Petri, A., & Sebin, K. (2003). Naglyadnaya statistika v meditsine [Tekst] : ucheb. posobiye: Per. s angl.– Visual statistics in medicine [Text]: textbook Transl. from English. Moscow : GEOTAR-MED [in Russian].
Thibodeau, J.T., Turer, A.T., Gualano, S.K., Ayers, C.R., Velez-Martinez, M., Mishkin, J.D., …, Drazner, M.H. (2014). Characterization of a novel symptom of advanced heart failure: bendopnea. JACC Heart Fail., 2(1), 24-31. DOI: 10.1016/j.jchf.2013.07.009. Epub 2014 Jan 8. PMID: 24622115.
Brandon, N. (2014). Characterization of a novel symptom of advanced heart failure: bendopnea. JACC Heart Fail.,2(5), 540. DOI: 10.1016/j.jchf.2014.05.009. PMID: 25301158.
Falk, R.H. (2014). "Bendopnea" or "kamptopnea?": Some thoughts on terminology and mechanisms. JACC Heart Fail. 2(4), 425. DOI: 10.1016/j.jchf.2014.03.011. PMID: 25103981.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Achievements of Clinical and Experimental Medicine
This work is licensed under a Creative Commons Attribution 4.0 International License.
