INFLUENCE OF EXOCRINE INSUFFICIENCY OF PANCREAS ON THE COURSE OF PRIMARY OSTEOARTHRITIS UNDER CONDITIONS OF COMORBIDITY
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i1.11721Keywords:
primary osteoarthritis, exocrine insufficiency of the pancreasAbstract
Lesions of the gastrointestinal tract (GIT), accompanied by a decrease in excretory function of the pancreas (PF), are frequent pathological processes that accompany primary OA as comorbid conditions.
The aim – to study the parameters of joint pain and their relationship with indicators of the excretory function of the pancreas in patients with primary OA with comorbid conditions.
Material and methods. We examined 174 outpatients with primary OA in combination with diseases accompanied by the decreased excretory function of the pancreas, in a state of complete and incomplete clinical remission.
Results. Analysis of the obtained indicators of fecal α-elastase content of patients showed a decrease in excretory function of the pancreas in the study group – (64.24±5.85) μg/g – compared with the control group (212.71±4.65) μg/g) (p<0.05). The indicator of YOUR at rest was (25.54±3.42) mm, the indicator of YOUR at movements – (38.81±4.41) mm. It was found that there are statistically significant medium-strength correlations between correlation pairs.
Conclusions. The identified correlations proved the interdependence and severity between the decrease in excretory function of the pancreas and the severity of joint pain in patients with primary OA.
References
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