MORPHOFUNCTIONAL CHANGES IN LUNGS AND LIVER IN THE EARLY PERIOD AFTER TRAUMATIC MUSCLE INJURY IN THE EXPERIMENT
DOI:
https://doi.org/10.11603/1811-2471.2020.v.i1.11072Keywords:
traumatic muscle damage, liver, lungsAbstract
An urgent issue today is traumatism, which remains an urgent problem in modern medicine, as there are high levels of disability and mortality among trauma victims.
The aim – to study peculiarities of morphological changes in lungs and liver in traumatic muscle injury in experimental study.
Material and Methods. The dynamics of morphological changes were investigated in an experimental model of traumatic muscle injury in 60 adult nonlinear rats, which were divided into two groups: intact and experimental. Morphological changes in lung and liver tissues were investigated in the early post-traumatic period for the first and seventh days.
Results and Discussion. Histological examination of liver and lung tissues on the first day of the post-traumatic period revealed structural changes that were manifested by marked circulatory disorders and with subsequent development of dystrophic-necrotic changes, which reached a maximum by the seventh day of the experiment.
Conclusions. In traumatic muscle lesions in experimental animals, structural changes in the liver and lungs begin to develop from the first day of the experiment throughout the study period and are manifested by marked circulatory disorders and the development of dystrophic-necrotic changes, especially in epithelial maxima, reaching maximal structures.
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