SOME SPECIFIC FEATURES OF THE MUSCULOSKELETAL SYSTEM DAMAGE, ASSOCIATED WITH LYME DISEASE IN THE INHABITANTS OF TERNOPIL REGION
DOI:
https://doi.org/10.11603/1811-2471.2019.v0.i1.10073Keywords:
Lyme borreliosis, joints, inhabitants, Ternopil regionAbstract
The aim of the study – to learn the features of clinical manifestations of musculoskeletal system damage of the inhabitants of Ternopil region infected with Borrelia burgdorferi.
Material and Methods. The present studies were conducted based on 58 inhabitants of Ternopil region with diseases of the musculoskeletal system infected with Borrelia burgdorferi. The age of tested persons ranged from 16 to 68 years. According to the presence of antibodies against Borrelia burgdorferi s.l, all patients were divided into two groups: the group 1 – 30 forestry workers of Ternopil region, the group 2 – 28 patients with musculoskeletal system diseases. Among all tested patients was examined for the presence of anti-Borrelia burgdorferi s.l. antibodies with the use of ELISA test, determining the level of specific IgM and IgG immunoglobulins. Quantitative articular score (the total numerical expression of pain and swelling of the joints) was used to evaluate the impression of the joints.
Results. In the study group, 30 (66.6 %) of the forestry workers and 4 (14.8 %) patients of the respondents had been bitten repeatedly, 8 (26.6 %) patients of group 1 and 2 (7.4 %) of the second one, were bitten twice, while the remaining 29.6 % do not remember being bitten in their lifetime. Combined impression of large and small joints were tested in 15 (48.3 %) out of 28 patients with musculoskeletal system, whereas in forestry workers, major injuries of the joints were prevalent in 15 (50.0 %) out of 30 examined. Positive or doubtful result in at least one class of antibodies IgM/IgG was observed in 14 (46.7 %) out of 30 forest workers of Ternopil region and 7 (25.0 %) of 28 patients with diseases of the musculoskeletal system.
Conclusions. The analysis of the effects of Borrelia burgdorferi sensu lato on the musculoskeletal system of the forestry workers and inhabitants of Ternopil region was carried out for the first time. In 33.3 % of examined both groups, who did not remember the tick bites, positive or intermediate results of at least one class of specific antibodies against Borrelia burgdorferi sensu lato were diagnosed, and clinical signs of the impression of the musculoskeletal system were observed. Major injuries of the joints were prevalent in 50.0 % of the forestry workers of Ternopil region infected with Lyme borreliosis, while 53.6 % of the examined patients disturbed the combined impression of large and small joints.
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