THE ROLE OF PANCREAS EXOCRINE FUNCTION AND OTHER PARAMETERS ON THE TROPHOLOGICAL STATUS OF PATIENTS WITH CHRONIC PANCRETITIS

Authors

  • L. S. Babinets I. Horbachevsky Ternopil State Medical University
  • Yu. Ya. Kotsaba I. Horbachevsky Ternopil State Medical University
  • I. M. Halabitska I. Horbachevsky Ternopil State Medical University

DOI:

https://doi.org/10.11603/1811-2471.2019.v0.i1.10041

Keywords:

chronic pancreatitis, trophological status, exocrine function of the pancreas, anemia, correlation and regression analysis, shear wave elastography

Abstract

Trophological insufficiency is polynutrient in its composition, i. e. lacking macro components (proteins, fats, carbohydrates) and micro components (vitamins and some chemical elements) in different ratios.

The aim – to evaluate correlations between indicators of trophological status and the main disease characteristics in patients with chronic pancreatitis.

Materials and Methods. 115 patients with chronic pancreatitis were examined comparable to etiological factor and socio-economic conditions and nutrition. There were 75 women and 40 men, the average age of patients was (52.4±3.2) years, the average duration of the disease was (12.8±3.1) years.

Conclusions. According to the data of correlation and regression analysis, it has been proved that the age of patients, disease duration, functional ability of the pancreas in terms of fecal α-elastase and structural state of the pancreas by the criteria of ultrasound in points and by the method of shear wave elastography are predictors of the development and progression of anemia, hypoproteinemia and vitamin deficiencies for the patients with chronic pancreatitis. Thats should be considered in clinical practice to form the most effective medical complex.

References

Вabinets, L.S., Halabitska, I.M., & Kytsai, K.Yu. (2014). Patogenetic substantiation of trofologic impact of complex therapy of chronic pancreatitis. Journal of Health Sciences, 4 (16), 272-275.

Löhr, J.-M., Klöppel, G., Riemann, J.F., Fischbach, W., Galle, J., & Mössner, J. (2008). Pankreas: Anatomie, Histologie, Embriologie, Entwicklungsanomalien. Gastroenterologie. Stuttgart, Thieme Verlag.

Domínguez-Muñoz, J.E., Iglesias-García, J., Iglesias, Rey M., Figueiras, A., & Vilariño-Insua, M. (20050. Effect of the administration schedule on the therapeutic efficacy of oral pancreatic enzyme supplements in patients with exocrine pancreatic insufficiency: a randomized, three-way crossover study. Aliment Pharmacol. Ther., 21 (8), 993-1000.

Вabinets, L.S., Halabitska, I.M., Kotsaba, Y.Y., Borovyk, I.O., & Migenko, B.O. (2017). The effect of the proteolisis' system activity for the trophological status of patients with osteoarthrosis and excretory insufficiency of pancreas. Wiadomosci lekarskie (Warsaw, Poland: 1960), 71 (2; 1), 273-276.

Published

2019-04-22

How to Cite

Babinets, L. S., Kotsaba, Y. Y., & Halabitska, I. M. (2019). THE ROLE OF PANCREAS EXOCRINE FUNCTION AND OTHER PARAMETERS ON THE TROPHOLOGICAL STATUS OF PATIENTS WITH CHRONIC PANCRETITIS. Achievements of Clinical and Experimental Medicine, (1), 14–16. https://doi.org/10.11603/1811-2471.2019.v0.i1.10041

Issue

Section

Оригінальні дослідження