PLASMAL LEVEL OF ALDEOSTERONE IN PATIENTS WITH HYPERTONIC DISEASE IN DEPEDENCE FROM GENDER-ANNUAL AND CLINICAL CHARACTERISTICS

Authors

  • T. P. Onyshсhuk M. Pyrohov Vinnytsia National Medical University, Vinnytsia, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2018.3.9755

Keywords:

arterial hypertension, aldosterone, dyslipidemia

Abstract

Purpose: determination of plasma level of aldosterone in patients with hypertension stage II and existing risk factors (RF).

Materials and Methods. The main group of the surveyed was 160 patients with hypertension stage 2 of different sex, aged 19 to 60 years, the control group – 27 practically healthy, aged 19 to 56 years. The level of aldosterone was determined by ELISA assay using IBL International GmbH (Canada) reagents.

Results. Significantly higher aldosterone levels were shown: in hypertensive patients with stage 2 of young and middle age compared with those who were practically healthy (293 vs 32 pg / ml, p <0.0001); in patients with hypertension stage 2 and 3 in comparison with stage 1; with abdominal obesity in comparison with patients without obesity; in cases with optimal and overweight in comparison with abdominal obesity; in patients with dyslipidemia in comparison with the normal level of proatherogenic lipids; in cases with absent and one RF in comparison with 2-4 RF.

Conclusions. The study of the effect of aldosterone on the development of changes in the cardiovascular system against the background of arterial hypertension in the gender-age aspect and the availability of RF will provide an opportunity to improve the algorithms for diagnosis and detection of patients with hypertension.

Author Biography

T. P. Onyshсhuk, M. Pyrohov Vinnytsia National Medical University, Vinnytsia, Ukraine

assistant of the department of therapy with the course of general practice and family medicine of the faculty of postgraduate education of Vinnitsa National Medical University named after N.I. Pirogov, Khmelnitsky, Ukraine

References

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Published

2019-01-28

How to Cite

Onyshсhuk T. P. (2019). PLASMAL LEVEL OF ALDEOSTERONE IN PATIENTS WITH HYPERTONIC DISEASE IN DEPEDENCE FROM GENDER-ANNUAL AND CLINICAL CHARACTERISTICS. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (3), 10–16. https://doi.org/10.11603/1681-2786.2018.3.9755

Issue

No. 3 (2018)

Section

Health of the population:tendencies and forecasts

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