CHANGES IN ADAPTIVE CAPABILITIES OF PATIENTS WITH BIPOLAR AFFECTIVE DISORDER AS A CONSEQUENCE OF DISORDERED COGNITIVE FUNCTIONING

Authors

  • M. S. Mysula I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • E. Yu. Mysula I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • E. P. Sas I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • L. M. Sas I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2023.4.14430

Keywords:

bipolar affective disorder, primary episode, cognitive functioning, adaptation capabilities

Abstract

Purpose: to investigate the features of cognitive functioning of patients with primary episode of bipolar disorder, taking into account sex and clinical variant.

Materials and Methods. According to the method of “Remembering the Ten Words”, 153 patients were examined: with prevalence of depressive symptoms (44 men and 75 women), with prevalence of manic symptoms (15 men and 8 women) and with simultaneous presence of depressive and manic symptoms or with rapid change of phases (6 men and 5 women). Statistical analysis was performed using the non-parametric Mann-Whitney test.

Results. It was found that in the depressive variant, the memorization curve was characterized by difficulties of fixing information and difficulty in holding it: 4.2±1.2 words, 4.6±1.4 words, 5.9±1.8 words, 5.8±1.4 words, 4.4±1.3 words, 2.6±1.4 words (in men 4.2±1.4 words, 4.6±1.5 words, 6.1±1.9 words, 5.7±1.5 words, 4.4±1.3 words, 2.6±1.4 words, women 4.2±1.1 words, 4.5±1.4 words, 5,9±1.7 words, 5.8±1.3 words, 4.4±1.3 words, 2.5±1.3 words); at manic - rapid rise with subsequent decrease and the lowest reproduction rates in an hour: 4.7±1.3 words, 7.5±1.3 words, 7.2±1.3 words, 6.7±1.8 words , 4.7±1.0 words, 2.0±1.0 words (men 4.9±1.3 words, 7.3±1.3 words, 7.1±1.2 words, 6, 3±1.7 words, 4.7±0.9 words, 1.9±0.9 words, women 4.3±1.4 words, 7.9±1.4 words, 7.5±1,5 words, 7.5±1.7 words, 4.6±1.3 words, 2.3±1.2 words); when mixed – combined fixation difficulties and low reproduction rates: 4.5±0.9 words, 5.1±1.3 words, 5.9±1.1 words, 5.6±0.8 words, 4.2±1.1 words, 2.4±0.9 words (in men 4.5±0.8 words, 5.5±1.0 words, 5.8±1.0 words, 5.8±0, 8 words, 4.5±1.0 words, 2.0±0.9 words, women 4.6±1.1 words, 4.6±1.5 words, 6.0±1.4 words, 5.4±0.9 words, 3.8±1.1 words, 2.8±0.8 words).

Conclusions. Certain differences in cognitive impairment were found depending on the clinical version of the primary episode; however, the differences between men and women are insignificant. Further prospects are related to the improvement of methods for predicting and treating cognitive impairment in bipolar disorders n order to improve the adaptation capabilities of patients and their quality of life.

Author Biographies

M. S. Mysula, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Medicine), Assistant at the department of propaedeutics of internal medicine and phthisiology, I. Horbachevsky Ternopil National Medical University

E. Yu. Mysula, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

is a 1st-year student specialty «Medicine» of the I. Horbachevsky Ternopil National Medical University

E. P. Sas, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

is a 1st-year student specialty «Medicine» of the I. Horbachevsky Ternopil National Medical University

L. M. Sas, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Medicine), Associate Professor of the Department of Psychiatry, Narcology and Medical Psychology, I. Horbachevsky Ternopil National Medical University

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Published

2024-02-13

How to Cite

Mysula, M. S., Mysula, E. Y., Sas, E. P., & Sas, L. M. (2024). CHANGES IN ADAPTIVE CAPABILITIES OF PATIENTS WITH BIPOLAR AFFECTIVE DISORDER AS A CONSEQUENCE OF DISORDERED COGNITIVE FUNCTIONING. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (4), 71–75. https://doi.org/10.11603/1681-2786.2023.4.14430

Issue

No. 4 (2023)

Section

The science for health care practice

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