THE INFLUENCE OF CLIMATE CONDITIONS ON SEASONAL CHANGES IN THE LEVEL OF GLYCATED HEMOGLOBIN IN PATIENTS WITH TYPE II DIABETES MELLITUS, WHO ARE ON OUTPATIENT TREATMENT

Authors

  • L. I. Malinovska I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • L. B. Romanyuk I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • Т. І. Pyatkovskyy I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • S. V. Senko LLC “Medical Laboratory Panakeyaˮ, Ternopil, Ukraine
  • N. Ya. Kravets I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2023.2.14030

Keywords:

diabetes, glycated hemoglobin, seasonal temperature changes, global warming

Abstract

Purpose: to determine the influence of climatic conditions, in particular temperature, in connection with the change of seasons, based on the results of a retrospective analysis of requests for determination of the level of glycated hemoglobin of patients in the LLC “Medical Laboratory Panakeyaˮ; to study the gender and age structure of patients with type II DM.

Materials and Methods. An analysis of information resources on the issue of the connection between changes in climatic conditions and the health status of patients with diabetes mellitus, pathogenetic mechanisms of the influence of environmental temperature on the level of glycemia was carried out, and information was collected and processed on the results of similar studies.

Results. The data of the literature review on the influence of ambient temperature on the health status of patients with DM are quite contradictory. According to the results of our analysis, the age range with the maximal number of patients with DM was 60–70 years, while the smallest number of patients was noted in the 20–30 years age range. Men significantly outnumbered women in the age group of 40–50 years and among children and adolescents, while women outnumbered men in the age groups of 20–30 years and 70 and older. Only 8.0 % of the participants had glycated hemoglobin indicators that corresponded to the normal range, while 14.0 % had indicators corresponding to the prediabetic state; the remaining 78.0 % had active diabetes. In November and December, the number of patients with elevated HbA1c decreases by 22.0 % and 26.0 %, respectively, compared to October. However, it increased significantly in January and remained at the same level throughout the spring months with a downward trend, but increases again during the summer months. Such results correspond to the data of the literature regarding the influence of temperature on the health status of patients with diabetes mellitus.

Conclusions. The maximal frequency of requests for determination of HbA1c levels in serum is noted in the age group of 60–70 years, with almost the same frequency in both men and women. In November and December, the number of patients with elevated HbA1c decreases in comparison with October, but increases in January. In the warm season, the level of HbA1c is significantly higher, which indicates a more negative effect of high temperatures on the health of the patients with diabetes.

Author Biographies

L. I. Malinovska, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

is a 2nd-year student of the I. Horbachevsky Ternopil National Medical University

L. B. Romanyuk, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Medicine), Associate Professor of the Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University

Т. І. Pyatkovskyy, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Medicine), Associate Professor of the Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University

S. V. Senko, LLC “Medical Laboratory Panakeyaˮ, Ternopil, Ukraine

head of the laboratory of Panakeya Medical Laboratory LLC

N. Ya. Kravets, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Biological sciences), Associate Professor of the Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University

References

(2014). American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care, 37(1), S81-S90. DOI: https://doi.org/10.2337/dc14-S081

Dain, K., & Hadley, L. (2012). Diabetes and climate change–two interconnected global challenges. Diabetes Res. Clin. Pract., 97(2), 337-339. DOI: https://doi.org/10.1016/j.diabres.2012.07.002

Paneni, F., Beckman, J.A., Creager, M.A., & Cosentino, F. (2013). Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Eur. Heart J., 34(31), 2436-2443. DOI: https://doi.org/10.1093/eurheartj/eht149

Blauw, L.L., Aziz, N.A., Tannemaat, M.R., Blauw, C.A., de Craen, A.J., Pijl, H., & Rensen, P.C. (2017). Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature. BMJ Open Diabetes Res. Care, 5(1). DOI: https://doi.org/10.1136/bmjdrc-2016-000317

Ackermann, R.T., Cheng, Y.J., Williamson, D.F., & Gregg, E.W. (2011). Identifying adults at high risk for diabetes and cardiovascular disease using hemoglobin A1c National Health and Nutrition Examination Survey 2005–2006. Am. J. Prev. Med., 40, 11-17. DOI: https://doi.org/10.1016/j.amepre.2010.09.022

Chen, Z., Shao, L., Jiang, M., Ba, X., Ma, B., & Zhou, T. (2022). Interpretation of HbA1c lies at the intersection of analytical methodology, clinical biochemistry and hematology (Review). Exp. Ther. Med., 24(6), 707. DOI: https://doi.org/10.3892/etm.2022.11643

Maliszewska, K., & Kretowski, A. (2021). Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis. Int. J. Mol. Sci., 22(4), 1530. DOI: https://doi.org/10.3390/ijms22041530

Worku, M.G., Seretew, W.S., Angaw, D.A., & Tesema, G.A. (2020). Prevalence and Associated Factor of Brown Adipose Tissue: Systematic Review and Meta-Analysis. Biomed. Res. Int., 2020. DOI 9106976. DOI: https://doi.org/10.1155/2020/9106976

Ratter-Rieck, J.M., Roden, M., & Herder, C. (2023). Diabetes and climate change: current evidence and implications for people with diabetes, clinicians and policy stakeholders. Diabetologia, 25, 1-13. DOI: https://doi.org/10.1007/s00125-023-05901-y

Schwartz, J. (2005). Who is Sensitive to Extremes of Temperature? A Case-Only Analysis. Epidemiology, 16(1), 67-72. DOI: https://doi.org/10.1097/01.ede.0000147114.25957.71

Gucciardi, E., Vahabi, M., Norris, N., Del Monte, J.P., & Farnum, C. (2014). The Intersection between Food Insecurity and Diabetes: A Review. Curr. Nutr. Rep., 3(4), 324-332. DOI: https://doi.org/10.1007/s13668-014-0104-4

Zilbermint, M. (2020). Diabetes and climate change. J. Community Hosp. Intern. Med. Perspect., 10(5), 409-412. DOI: https://doi.org/10.1080/20009666.2020.1791027

Published

2023-08-24

How to Cite

Malinovska, L. I., Romanyuk, L. B., Pyatkovskyy Т. І., Senko, S. V., & Kravets, N. Y. (2023). THE INFLUENCE OF CLIMATE CONDITIONS ON SEASONAL CHANGES IN THE LEVEL OF GLYCATED HEMOGLOBIN IN PATIENTS WITH TYPE II DIABETES MELLITUS, WHO ARE ON OUTPATIENT TREATMENT. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (2), 20–26. https://doi.org/10.11603/1681-2786.2023.2.14030

Issue

Section

Health and society