COMPARATIVE ANALYSIS OF THE COURSE OF THE DISEASE OF COVID-19 IN PATIENTS NOT VACCINATED AND VACCINATED WITH PFIZER-BIONTECH OR MODERNA

Authors

  • O. O. Kulyanda I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • O. S. Bilovus I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • R. I. Zaremba I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • O. V. Denefil I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2023.2.14029

Keywords:

vaccine, Pfizer-BioNTech, Moderna, health, COVID-19, complications

Abstract

Purpose: to evaluate the effect of vaccination with mRNA vaccines on the severity of the course for the disease of COVID-19, the level of hospitalization and distribution of virus.

Materials and Methods. The results of questionnaires and surveys of people were used in the study. The methods of comparative, systemic analyses were used.

Results. Our study included 1038 participants, of which 576 were vaccinated and 462 were unvaccinated. Among the vaccinated people, 21 had pneumonia, 18 had hypercoagulation, 34 had multiple organ failure, and 26 had post-COVID-19 syndrome.

Among unvaccinated people, 163 had pneumonia, 118 had hypercoagulation, 147 had multiple organ failure, and 197 had post-COVID-19 syndrome.

Conclusions. The effectiveness of the Pfizer-BioNTech vaccine had a major impact on the course of the pandemic. Vaccines stimulate the immune system and provoke the creation of highly specialized antibodies and the recruitment of T-killers, which counteract the massive replication of the virus, and therefore facilitate the clinical course of the disease and the presence of symptoms. In addition, it helped reduce transmission rates, providing protection against asymptomatic infections. This allowed countries to begin rebuilding their economies and protect people from serious complications of the disease.

Author Biographies

O. O. Kulyanda, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

PhD (Medicine), Associate Professor of the Department of Pathological Physiology, I. Horbachevsky Ternopil National Medical University

O. S. Bilovus, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

is a 3rd-year student of the I. Horbachevsky Ternopil National Medical University

R. I. Zaremba, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

is a 3rd-year student of the I. Horbachevsky Ternopil National Medical University

O. V. Denefil, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

DM (Medicine), Professor, Head of the department of pathological physiology, I. Horbachevsky Ternopil National Medical University

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Published

2023-08-24

How to Cite

Kulyanda, O. O., Bilovus, O. S., Zaremba, R. I., & Denefil, O. V. (2023). COMPARATIVE ANALYSIS OF THE COURSE OF THE DISEASE OF COVID-19 IN PATIENTS NOT VACCINATED AND VACCINATED WITH PFIZER-BIONTECH OR MODERNA. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (2), 12–19. https://doi.org/10.11603/1681-2786.2023.2.14029

Issue

No. 2 (2023)

Section

Health and society

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