THE ROLE AND PROBLEMS OF POSTHUMOUS DONATION

Authors

  • M. S. Zagriichuk Heart Institute of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • I. P. Marchuk Volyn Regional Clinical Hospital, Lutsk, Ukraine Lesya Ukrainka Volyn National University, Lutsk, Ukraine
  • O. O. Pidoprygora O. O. Shalimov National Institute of Surgery and Transplantology of National Academy of Sciences of Ukraine, Kyiv, Ukraine
  • T. S. Migalega O. O. Shalimov National Institute of Surgery and Transplantology of National Academy of Sciences of Ukraine, Kyiv, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2022.4.13677

Keywords:

organ donation, explantation, brain death, organ transplantation

Abstract

Purpose: to determine the dependence of the number of organ explantations in effective post-mortem donors on age and laboratory results and to study the proportion of organs suitable for transplantation in the latter.

Materials and Methods. The study included 14 post-mortem donors who underwent organ explantation from May 2021 to December 2021 at the KNP KOCL, of which 56.3 % were men and 43.7 % were women. By age, the patients were divided into 2 groups: group 1 – under 50 years old, group 2 – 50 years and older.

Results. According to the results of statistical processing of data, it can be argued that the groups did not differ significantly for the article, body mass index, duration of stay in HRIT, and such laboratory parameters as the average level of creatinine, sodium, ALT and AST, at the same time there was a significant difference in the content of urea and directly after age, p=0.03 and p=0.000034, respectively. There was no significant statistical difference in the number of explantations.

Conclussions. The modern development of transplantation in our country has made it possible to significantly improve the results in the fight for the lives of patients. Posthumous donation saves the life of at least 4 people at the same time. In Ukraine, there are no criteria for marginal donation, extended criteria for donation, and there is no unified protocol for conditioning a potential donor. The age of the post-mortem donor is not a critical criterion for organ donation. Despite laboratory indicators of donor safety, some organs are not suitable for further transplantation; in this study, these are 36 % of hearts, 43 % of livers and 7 % of kidneys. Follow-up studies in a larger cohort of patients are needed to further explore the effectiveness of donor use and post-transplant long-term outcomes.

Author Biographies

M. S. Zagriichuk, Heart Institute of the Ministry of Health of Ukraine, Kyiv, Ukraine

head of the kidney transplantation and hemodialysis department, transplant surgeon, Heart Institute of the Ministry of Health of Ukraine, Kyiv

I. P. Marchuk, Volyn Regional Clinical Hospital, Lutsk, Ukraine Lesya Ukrainka Volyn National University, Lutsk, Ukraine

surgeon of the department of organ transplantation, liver and pancreas surgery of Volynian regional clinical hospital, senior lecturer of the Department of Clinical Medicine of Lesya Ukrainka Volyn National University

O. O. Pidoprygora, O. O. Shalimov National Institute of Surgery and Transplantology of National Academy of Sciences of Ukraine, Kyiv, Ukraine

surgeon, O.O. Shalimov National Institute of Surgery and Transplantology of National Academy of Sciences of Ukraine, Kyiv

T. S. Migalega, O. O. Shalimov National Institute of Surgery and Transplantology of National Academy of Sciences of Ukraine, Kyiv, Ukraine

gastroenterologist, transplant coordinator of the department of organ transplantation, liver and pancreas surgery of Volynian regional clinical hospital

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Published

2023-04-05

How to Cite

Zagriichuk, M. S., Marchuk, I. P., Pidoprygora, O. O., & Migalega, T. S. (2023). THE ROLE AND PROBLEMS OF POSTHUMOUS DONATION. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (4), 18–23. https://doi.org/10.11603/1681-2786.2022.4.13677

Issue

No. 4 (2022)

Section

Health and society

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Copyright (c) 2023 Bulletin of Social Hygiene and Health Protection Organization of Ukraine

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