SLEEVE GASTRECTOMY IN PATIENTS WITH MORBID OBESITY: IMPACT ON LIPID PROFILE
DOI:
https://doi.org/10.11603/1681-2786.2019.2.10482Keywords:
morbid obesity, dyslipidemia, sleeve gastrectomy, resultsAbstract
Purpose: to investigate the effect of sleeve gastrectomy on lipid profile in morbidly obese patients with preoperative dyslipidemia.
Materials and Methods. The basis of the study was the materials of clinical examination and surgical treatment of 105 morbidly obese patients (47 men and 58 women, mean age (41.8±12.4) years who underwent sleeve gastrectomy.
Results. Dyslipidemia was diagnosed preoperatively in 86 (81.9 %) patients. Regular use of lipid-lowering drugs in 44 (51.1 %) patients before surgery did not lead to normalization or significant improvement of lipidogram parameters. The procedure led to decrease in the mean total cholesterol level from (5.73±1.0) to (4.92±0.5) mmol/l, triglycerides from (1.91±0.9) to (1.43±0.3) mmol/l, regression coefficient of atherogenicity from (3.84±0.8) to (2.9±0.6) in 60 months after surgery (P < 0.05). In 60 months after a gastric resection of the stomach, dyslipidemia (in all type 2a) was diagnosed in 15 (62.5 %) patients of the main group with preoperative lipid metabolism, in 9 (37.5 %) patients the lipidogram parameters were normalized in patients with morbid obesity, which indicates the effectiveness of the surgery.
Conclusions. Sleeve gastrectomy is effective method for correction of dyslipidemia in morbidly obese patients. The implementation of this intervention results in a significant and persistent (5-year postoperative observation) reduction in the average level of total cholesterol, triglycerides and atherogenic factor.
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