EFFECTIVENESS OF HYSTEROREZECTOSCOPY IN WOMEN WITH INFERTILITY AND UTERINE FIBROIDS IN PROGRAMS OF ASSISTED REPRODUCTIVE TECHNOLOGIES

Authors

  • S. V. Khmil I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine
  • Yu. B. Drozdovska I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine
  • M. S. Khmil I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine
  • N. Ya. Chudiyovych Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine

DOI:

https://doi.org/10.11603/1681-2786.2018.4.10030

Keywords:

uterus fibroid, hysterorezectoscopy, agonists of gonadotrophin-releasing hormones, infertility, assisted reproductive technologies, in vitro fertilization, intracytoplasmatic sperm injection

Abstract

Purpose: studying of the effectiveness of hysterorezectoscopy in women with infertility and uterine fibroids in the cycles of in vitro fertilization.

Materials and Methods. A randomized clinical trial was conduct among 58 women undergoing infertility treatment using assisted reproductive technologies (ART). The selection was divided into 2 groups. The group 1 (study) consisted of 41 women with uterus fibroids with submucosal and submucosally-intramural placement of myomatous nodes and failed attempts of IVF in history, these women were offered hysterorezectoscopy, as preparation for programs of assisted reproductive technologies. The froup 2 (control) – 17 women with uterine fibroids with submucosally-intramural placement of myomatous nodes, who refused hysterorezectoscopy. In this study, couples were included exclusively with female infertility.

Results. The effectiveness of hysterorezectoscopy on the outcome of IVF cycles in women with uterine fibroids was proved. In the study group, 17 women had an onset of pregnancy, which was 41.5 % (after I attempted IVF), early spontaneous miscarriages were observed in 2 women (11.8 %), in 14 women pregnancy ended in timely partum (82.4 %) and 1 woman had premature partum (5.9 %). In the control group pregnancy occurred in 6 women (35.3 %), 3 cases of early spontaneous miscarriages (50 %), timely births in 3 women (50 %).

Conclusions. The uterine fibroids is basically a cause of infertility due to a mechanical factor. Hysterorezectoscopy is the best method of pregravid preparation in women with uterine fibroids, undergoing infertility treatment during the use of assisted reproductive technologies. Hysterorezectoscopy is an organ saving operation that has several advantages: a mild postoperative period, a lack of adhesive process, which in turn increases the incidence and onset of pregnancy.

Author Biographies

S. V. Khmil, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine

Professor at the Department of Obstetrics and Gynecology №1 of I.Horbachevsky Ternopil State Medical University. Merited Figure of Science and Technology of Ukraine, Professor, Doctor of Medical Science, Director of the medical Center «The Clinic of Professor Stefan Khmil»

Yu. B. Drozdovska, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

Postgraduate Student at the Department of Obstetrics and Gynecology №1 of I.Horbachevsky Ternopil State Medical University

M. S. Khmil, I. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine

Postgraduate Student at the Department of Obstetrics and Gynecology №1 of I.Horbachevsky Ternopil State Medical University

N. Ya. Chudiyovych, Medical Center “Professor S. Khmil Clinic”, Ternopil, Ukraine

Doctor intern at the Ternopil Regional Perinatal Center «Mother and Child»

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Published

2019-04-18

How to Cite

Khmil, S. V., Drozdovska, Y. B., Khmil, M. S., & Chudiyovych, N. Y. (2019). EFFECTIVENESS OF HYSTEROREZECTOSCOPY IN WOMEN WITH INFERTILITY AND UTERINE FIBROIDS IN PROGRAMS OF ASSISTED REPRODUCTIVE TECHNOLOGIES. Bulletin of Social Hygiene and Health Protection Organization of Ukraine, (4), 51–55. https://doi.org/10.11603/1681-2786.2018.4.10030

Issue

No. 4 (2018)

Section

The science for health care practice

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