DYNAMICS OF PERIODONTAL TISSUES MICROBIOCENOSIS UNDER THE COMPLEX TREATMENT OF CATARRHAL GINGIVITIS AND CHRONIC GASTRODUODENITIS IN THE ADOLESCENTS
Background. The key links in the etiology and pathogenesis of periodontal tissue diseases are the quantitative and qualitative changes in the composition of the microflora of oral cavity, with the simultaneous deterioration of oral hygiene, reduction of local and general immunity, which occurs more often in the presence of somatic diseases.
Objective. The aim of the research was to determine the clinical and microbiological efficacy of the developed treatment-prophylactic complex in the adolescents with catarrhal gingivitis and chronic gastroduodenitis before and after treatment.
Methods. Changes were made to and before the treatment of clinical parameters, gingival microbiocenosis of 38 adolescents with generalized catarrhal gingivitis and chronic gastroduodenitis aged 12-18 years old, who comprised the main group. In the comparison group 25 adolescents of similar age diagnosed with generalized catarrhal gingivitis without any somatic diseases were involved.
Results. It has been established that used combination (drug of plant origin with antimicrobial properties + dental gel with Metronidazole benzoate and Chlorhexidine digluconate + capsules of probiotics) yields the conventional treatment as well as exceeds it for examined clinical indicators and indexes. The treatment and prophylaxis with suggested complex have proved a significant positive effect on the gums microbiocenosis in adolescents with generalized catarrhal gingivitis and underlying concomitant gastroduodenitis.
Conclusions. The suggested therapeutic and prophylactic complex provides a reduction in the massiveness and colonization frequency of the gum mucosa by pathogenic aerobic microflora (β-hemolytic streptococcus, golden staphylococcus, and yeast-like Candida fungi).
Adler I, Muiño A, Aguas S, Harada L, Diaz M, Lence A, Labbrozzi M, Muiño JM, Elsner B, Avagnina A, Denninghoff V. Helicobacter pylori and oral pathology: relationship with the gastric infection. World Journal of Gastroenterology: WJG. 2014 Aug 7;20(29): 9922-35.
Barer GM, Zoryan EV, Agapov VS et al. Rational Pharmacotherapy in Dentistry. Medicine. 2010, р. 235-245. (In Russian).
Bogatu SI, Iaremenko II, Liubchenko OA, Shnaider SA, Levytskyy AP. An oral caivity condition in gastritis patients. Visnyk stomatologii. 2017;26(4): 23-26. (In Ukrainian).
Chapple IL, Van der Weijden F, Doerfer C, Herrera D, Shapira L, Polak D, Madianos P, Louropoulou A, Machtei E, Donos N, Greenwell H. Primary prevention of periodontitis: managing gingivitis. Journal of clinical periodontology. 2015 Apr;
Holt JG, Krige NR, Sneath PH. Bergey’s manual of bacteriology. London: Williams and Wilkins Press. 1994:1224-89.
Dychko EN, Kovach IV, Khotimska YuV, Fedoriak NV. Frequency of dental diseases in children. Medychni perspectyvy. 2012;17(2):114-16. (In Ukrainian).
Eisalhy M, Alsumait A, Behzadi S, Al-Mutawa S, Amin M. Children's perception of caries and gingivitis as determinants of oral health behaviours: a cross-sectional study. International journal of paediatric dentistry. 2015 Sep;25(5):366-74.
Krisenko OV, Sklyar TV, Voronkova OS, Sirokvasha OA, Shevchenko TM. Features of the composition of microbial associations and resistance to antibiotics of oral cavity microbiota. Microbiology and Biotechnology. 2014;1:35-44. (In Ukrainian).
Komarov FI, Korovkin BF, Menshikov VV. Biochemical studies in the clinic. Elista: Djangar. 1999; 999: 249. (In Russian).
da Silva PD, Barbosa TS, Amato JN, Montes AB, Gavião MB. Gingivitis, psychological factors and quality of life in children. Oral Health Prev Dent. 2015 Jan 1;13(3):227-35.
Leus PA, Yudin NA. Periodontal disease. Minsk; 2016, p.350. (In Belorussian).
Lin GH, Boynton JR. Periodontal Considerations for the Child and Adolescent. A Literature Review. The Journal of the Michigan Dental Association. 2015 Jan;97(1):36-42.
Maliy D, Antonenko M. Epidemiology of periodont diseases: age aspect. Ukrainian Scientifice Medical Youth Journal. 2013;4:41-43. (In Ukrainian).
Mashchenko I, Samoilenko V, Pyndus Т. Diagnostic and prognostic significance of parameters of biocenosis and local immunity in chronic catarrhal gingivitis in young men. Modern Dentistry. 2012;3:54-57. (In Ukrainian).
ereira SM, Pardi V, Cortellazzi KL, Ambrosano GM, Vettorazzi CA, Ferraz SF, Meneghim MD, Pereira AC. Geographic information system and multilevel analysis: gingival status among 12-year-old schoolchildren in São Paulo, Brazil. Revista Panamericana de Salud Pública. 2014;35:136-43.
Periodontal disease. More than just gums. Mayo Clinic Health Letter. (2014). 32;10: ZE01-4.
Romanenko EG. Type and frequencies of changes in oral cavity in children with chronic gastroduodenatis. Сhild health. 2012;1(36):70-73. (In Russian).
Savichuk NO. Correction of microecological disorders as part of treatment and prophylactic measures in children with chronic generalized catarrhal gingivitis. Delta Digest. 2015;1:5-8. (In Russian).
Song HJ. Periodontal considerations for children. Dental Clinics. 2013 Jan 1;57(1):17-37.
Tomazoni F, Zanatta FB, Tuchtenhagen S, da Rosa GN, Del Fabro JP, Ardenghi TM. Association of gingivitis with child oral health–related quality of life. Journal of periodontology. 2014 Nov;85(11): 1557-65.
Trufanova VP. Method of treatment of chronic catarrhal gingivitis in children. World of Medicine and Biology. 2017;2 (60):117-120. (In Russian).
Winning L, Linden GJ. Periodontitis and systemic disease: association or causality? Current oral health reports. 2017 Mar 1;4(1):1-7.
Xin X, Junzhi H, Xuedong Z. Oral microbiota: a promising predictor of human oral and systemic diseases. = Huaxi kouqiang yixue zazhi= West China journal of stomatology. 2015 Dec;33(6):555-60.
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