FLUORIDES AND ORAL HEALTH

Authors

  • S. I. Boitsaniuk I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE https://orcid.org/0000-0001-7742-1346
  • M. O. Levkiv I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE

DOI:

https://doi.org/10.11603/ijmmr.2413-6077.2022.2.13121

Keywords:

caries prevention, fluoride, mechanisms of action, fluoride side effects

Abstract

Background. The importance of fluorides in caries prevention is discussed in the article and practical recommendations for the use of fluoride containing products are presented.

Objectives. The primary objective of this systematic review is to assess the evidence on the comparative effectiveness of topical fluoride therapy (TFT) in the form of toothpastes, mouth rinses, gels and varnishes in prevention of dental caries in children and adolescents.

Methods. A systematic electronic literature search was conducted in the PubMed and Web of Science databases using search terms. Current reports in the literature concerning means and methods of use of fluoride-containing medications are considered.

Results. A large number of scientific studies, reviews based on them and meta-analyses conclude that the central element of caries prevention, on which the decrease in caries prevalence and caries experience is based, is the regular topical use of fluoride medications for oral cavity.

Conclusions. Topical use of fluorides is a key element in successful caries prevention.

Author Biographies

S. I. Boitsaniuk, I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE

PhD, MD, Associate Professor of the Department of Dental Therapy, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

M. O. Levkiv, I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE

PhD, MD, Associate Professor of the Department of Dental Therapy, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

References

Sheiham A, James, W. A new understanding of the relationship between sugars, dental caries and fluoride use: Implications for limits on sugars con­sum­ption. Public Health Nutrition. 2014;17(10):2176-84.

https://doi:10.1017/S136898001400113X

Horst JA, Tanzer JM, Milgrom PM. Fluorides and Other Preventive Strategies for Tooth Decay. Dent Clin North Am. 2018;62(2):207-34.

https://doi:10.1016/j.cden.2017.11.003

Toumba KJ, Twetman S, Splieth C, Parnell C, van Loveren C, Lygidakis NΑ. Guidelines on the use of fluoride for caries prevention in children: an updated EAPD policy document. Eur Arch Paediatr Dent. 2019;20(6):507-16.

https://doi:10.1007/s40368-019-00464-2

Fontana M, Carrasco-Labra A, Spallek H, Eckert G, Katz B. Improving Caries Risk Prediction Modeling: A Call for Action. J Dent Res. 2020;99(11): 1215-20.

https://doi:10.1177/0022034520934808

Featherstone JD. The caries balance: the basis for caries management by risk assessment. Oral Health Prev Dent. 2004;2 Suppl 1:259-64.

Benson PE, Parkin N, Dyer F, Millett DT, Furness S, Germain P. Fluorides for the prevention of early tooth decay (demineralised white lesions) during fixed brace treatment. Cochrane Database Syst Rev. 2013;(12).

https://doi:10.1002/14651858.CD003809.pub

Urquhart O, Tampi MP, Pilcher L, et al. Non­restorative Treatments for Caries: Systematic Review and Network Meta-analysis. J Dent Res. 2019;98(1):14-26.

https://doi:10.1177/0022034518800014

Cury JA, Tenuta LM. Enamel remineralization: controlling the caries disease or treating early caries lesions? Braz Oral Res. 2009;23 Suppl 1:23-30.

https://doi:10.1590/s1806-83242009000500005.

Jullien S. Prophylaxis of caries with fluoride for children under five years. BMC Pediatr. 2021;

(Suppl 1):351.

https://doi:10.1186/s12887-021-02702-

Khan, Ayyaz Ali. “Mechanisms of action of fluoride in dental caries.” (2002). Pakistan Oral & Dent. Jr. 22 (1) June 2002 49-54.

Tenuta LM, Zamataro CB, Del Bel Cury AA, Tabchoury CP, Cury JA. Mechanism of fluoride dentifrice effect on enamel demineralization. Caries Res. 2009;43(4):278-85.

https://doi:10.1159/000217860.

Fejerskov O. Concepts of dental caries and their consequences for understanding the disease. Community Dent Oral Epidemiol. 1997;25(1):5-12.

https://doi:10.1111/j.1600-0528.1997.tb00894.x.

Silverstone LM. Laboratory studies on the demineralization and remineralization of human enamel in relation to caries mechanisms. Aust Dent J. 1980;25(3):163-8.

https://doi:10.1111/j.1834-7819.1980.tb03707.x.

Stößer L. Die antibakterielle Wirkung der Fluoride auf die dentale Plaque. Oralprophylaxe Kinderzahnheilkd. 2006;28:170–177. Schiffner, U. Verwendung von Fluoriden zur Kariesprävention. Bundesgesundheitsbl 64, 830–7 (2021).

https://doi.org/10.1007/s00103-021-03347-4

Loskill P, Zeitz C, Grandthyll S, et al. Reduced adhesion of oral bacteria on hydroxyapatite by fluoride treatment. Langmuir. 2013;29(18):5528-33.

https://doi:10.1021/la4008558

Featherstone JD. Prevention and reversal of dental caries: role of low level fluoride. Community Dent Oral Epidemiol. 1999;27(1):31-40.

https://doi:10.1111/j.1600-0528.1999.tb01989.x

Cox SD, Lassiter MO, Miller BS, Doyle RJ. A new mechanism of action of fluoride on streptococci. Biochim Biophys Acta 1999; 1428(2-3): 415-23.

Federal Register. Proposed HHS Recom­mendation for Fluoride Concentration in Drinking Water for Prevention of Dental Caries (Volume 76, Number 9; pages 2383-2388). U.S. Department of Health and Human Services 2011. Accessed July 15, 2021.

U.S. Public Health Service Recommendation for Fluoride Concentration in Drinking Water for the Prevention of Dental Caries. Public Health Rep 2015;130(4):318-31.

ADA. Fluoridation Facts: American Dental Association; 2018.

Sampaio, F. C., & Levy, S. M. (2011). Systemic fluoride. Monographs in oral science, 22, 133–45.

https://doi.org/10.1159/000325161

Burt BA. Prevention policies in the light of the changed distribution of dental caries. Acta Odontol Scand. 2008;195:7-63.

Walsh T, Worthington HV, Glenny AM, Ma­rinho VC, Jeroncic A. Fluoride toothpastes of different concentrations for preventing dental caries. Coch­rane Database Syst Rev. 2019;3(3)

https://doi:10.1002/14651858.

Vogel GL. Oral fluoride reservoirs and the prevention of dental caries. Monogr Oral Sci. 2011;22:146-57.

https://doi:10.1159/000325166

Vogel GL, Shim D, Schumacher GE, Carey CM, Chow LC, Takagi S. Salivary fluoride from fluoride dentifrices or rinses after use of a calcium pre-rinse or calcium dentifrice. Caries Res. 2006;40:449–54.

https://doi:10.1159/000094293

Marinho VC, Chong LY, Worthington HV, Walsh T. Fluoride mouthrinses for preventing dental caries in children and adolescents. Cochrane Data­base Syst Rev. 2016;7(7):

https://doi:10.1002/14651858.

Arruda AO, Senthamarai Kannan R, Ingle­hart MR, Rezende CT, Sohn W. Effect of 5% Fluoride Varnish Application on Caries among School Children in Rural Brazil: A Randomized Controlled Trial. Community Dent Oral Epidemiol. 2012;40:267–76.

https://doi:10.1111/j.1600-0528.2011.00656.x

American Dental Association Council on Scientific Affairs. Professionally Applied Topical Fluoride, Evidence-based Clinical Recommendation. J Am Dent Assoc. 2006;137:1151–9.

Carey CM. Focus on fluorides: update on the use of fluoride for the prevention of dental caries. J Evid Based Dent Pract. 2014;14 Suppl:95-102.

https://doi:10.1016/j.jebdp.2014.02.004

Autio-Gold JT, Courts F. Assessing the effect of fluoride varnish on early enamel carious lesions in the primary dentition. J Am Dent Assoc. 2001;132(9):1247-318.

https://doi:10.14219/jada.archive.2001.0367

Ullah R, Zafar MS, Shahani N. Potential fluoride toxicity from oral medications: A review. Iran J Basic Med Sci. 2017;20(8):841-8.

https://doi:10.22038/IJBMS.2017.9104

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Published

2023-03-03

How to Cite

Boitsaniuk, S. I., & Levkiv, M. O. (2023). FLUORIDES AND ORAL HEALTH. International Journal of Medicine and Medical Research, 8(2), 67–73. https://doi.org/10.11603/ijmmr.2413-6077.2022.2.13121

Issue

Vol. 8 No. 2 (2022): International Journal of Medicine and Medical Research

Section

Dentistry

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