COMPARTMENTAL AND PERFUSIONAL APPROACHES FOR PHARMACOKINETICAL MODELS CONSTRUCTION

Authors

  • V. P. Martsenyuk Ternopil State Medical University named after I.Ya. Horbachevsky http://orcid.org/0000-0001-5622-1038
  • I. Ye. Andrushchak Ternopil State Medical University named after I.Ya. Horbachevsky

DOI:

https://doi.org/10.11603/mie.1996-1960.2008.3.7504

Abstract

The steps of models construction in pharmacokinetics are summarized in this work. Basic approaches to search the forms of compartmental and perfusional models are shown. At compartmental modeling the structure and kinetical parameters values are defined exceptionally by the way of formal analysis of drug kinetics within target tissue. Perfusional models are based on real physiological parameters of tissues, organs and systems of organism linked by bloodflow.

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How to Cite

Martsenyuk, V. P., & Andrushchak, I. Y. (2012). COMPARTMENTAL AND PERFUSIONAL APPROACHES FOR PHARMACOKINETICAL MODELS CONSTRUCTION. Medical Informatics and Engineering, (3). https://doi.org/10.11603/mie.1996-1960.2008.3.7504

Issue

No. 3 (2008)

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