NEW DIRECTIONS OF BIOMEDICAL INFORMATICS IN THE STRATEGY OF CHANGE OF PRACTICAL MEDICINE AND BIOMEDICAL EDUCATION. PRECISION MEDICINE AND BIOINFORMATICS OF THE INFLAMMATOR

Authors

  • L. Yu. Babintseva Shupyk National Medical Academy of Postgraduate Education
  • V. V. Krasnov Shupyk National Medical Academy of Postgraduate Education

DOI:

https://doi.org/10.11603/mie.1996-1960.2021.1.12188

Abstract

Background. The paper analyzes new areas of medical and biological informatics in terms of learning their materials and technology of knowledge transfer. The global purpose of these areas is to provide a link between the basic conceptual approaches and constructs of systems medicine and systems biology. The goal of the work is to present methods of highlighting the achievements of systemic biomedicine.

Materials and methods. Results. Two modern directions of development of systemic biomedicine are considered: "precision medicine" (as a purely medical trend) and bioinformatics of the inflammatory agent (as a purely biological trend). In precision medicine, the main focus is on determining which approaches will be effective for certain patients based on genetic, environmental and life factors. It is proposed to actively use specialized knowledge bases for knowledge transfer, which are also an important tool of bioinformatics to check the pathogenicity of the pathogen.

Conclusions. Researchers can use open data to study a wide range of diseases to better predict the risk of disease, understand its possible course, and find improved strategies for diagnosis and treatment. We regard precision medicine as a fundamentally new direction that enhances the effectiveness of practical medicine. The emergence of systemic biomedicine forces to radically change not only the methods of teaching material, assessing the assimilation of educational content, but also to pay much more attention to the standards of medical care.

References

Zubov, E.V., Gatautdinova, G.F., Gulyaeva, O.V. (2017). Medical information systems. Prospects for development. Actual problems of pediatrics: mater. mezhreg. scientific-practical conf. from intern. uch. 08 April 2017, Perm, 79-83.

Huser, V., Sincan, M., Cimino, J. J. (2014). Developing genomic knowledge bases and databases to support clinical management: current perspectives. Pharmgenomics Pers Med, 7, 275-283.

Precision Medicine Initiative: Data Security Policy Principles and Framework. - The white house. May 25, 2016.

Ashley, E. (2016). Towards precision medicine. Nat Rev Genet, 17, 507-522.

Deneke, C., Rentzsch, R., Renard, B. (2017). PaPrBaG: A machine learning approach for the detection of novel pathogens from NGS data: Sci Rep. Nature, 7, 39194.

Zankari, E. et al. (2012). Identification of acquired antimicrobial resistance genes. J. Antimicrob. Chemother, 67, 2640-2644.

Saeb, A. T. M., Khalid, A. Al-R., Abouelhoda, М. et al. (2017). Genome sequencing and analysis of the first spontaneous Nanosilver resistant bacterium Proteus mirabilis strain SCDR1. Antimicrobial Resistance & Infection Control, 6.

Saeb, A. T. M. (2018). Current Bioinformatics resources in combating infectious diseases. Bioinformation, 14 (1), 031-035.

Cosentino, S., Voldby, L. M., M0ller, A. F., Lund, O. (2013). PathogenFinder - Distinguishing Friend from Foe Using Bacterial Whole Genome Sequence Data. PLoS ONE, В (10), e77302.

Dixon-Woods, R. B., Charles, K., Dawson, J. et al. (2014). Culture and behaviour in the English National Health Service: overview of lessons from a large multimethod study. BMJ Qual. Saf., 23 (2), 106-115.

Published

2021-08-12

How to Cite

Babintseva, L. Y., & Krasnov, V. V. (2021). NEW DIRECTIONS OF BIOMEDICAL INFORMATICS IN THE STRATEGY OF CHANGE OF PRACTICAL MEDICINE AND BIOMEDICAL EDUCATION. PRECISION MEDICINE AND BIOINFORMATICS OF THE INFLAMMATOR. Medical Informatics and Engineering, (1), 31–35. https://doi.org/10.11603/mie.1996-1960.2021.1.12188

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Section

Articles