FEATURES ОF PSYCHOPATHOLOGICAL SYMPTOMS ІN PATIENTS WITH DEPRESSIVE DISORDERS
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2020.4.11799Keywords:
depressive disorders, psychopathological symptoms, SCL-90-R questionnaireAbstract
Summary. The study of the clinical phenomenology of depressive disorders is important for determining the directions of modern pathomorphosis, prognosis and treatment of depression.
The aim of the study – to investigate the structure and severity of psychopathological symptoms in patients with depressive disorders at the present stage, taking into account age and gender factor.
Materials and Methods. A clinical examination of 107 men and 138 women with endogenous depressive disorders (ICD-10 codes F 31.3, F 31.4, F 32.0, F 32.1, F 32.2, F 33.0, F 33.1, F 33.2), taking into account age and gender factor, using the questionnaire SCL-90-R was performed.
Results. Depressive disorders, in addition to depressive symptoms, are manifested by a wide range of psychopathological manifestations, among which are dominated by increased levels of anxiety (2.40±0.45) points, moderate levels of interpersonal sensitivity (1.73±0.48) points and obsessive-compulsive symptoms (1.44±0.85) points, close to moderate levels of somatization (1.05±0.51) points and phobic anxiety (1.00±0.47) points, as well as low levels of psychoticism (0.64±0.24) points, hostility (0.55±0.77) points and paranoid symptoms (0.26±0.13) points. Significantly higher rates of depression, hostility and paranoid symptoms were found in men, and anxiety, obsessive-compulsive symptoms, interpersonal sensitivity, somatization and phobic anxiety were found in women. Gender differences in the severity of psychopathological symptoms are probably related to different gender role models and the specifics of gender-based pathocharacterological changes. The severity of all psychopathological manifestations increases with age, with a more significant deterioration in the manifestations of psychopathological symptoms occurs at the age of 45 years and older.
Conclusions. The clinical picture of modern depressive disorders is characterized by polymorphic symptoms and the presence of significant gender differences; and psychopathological manifestations intensify with age, reaching the greatest severity in middle-aged, elderly and senile patients, which can be seen as a manifestation of modern clinical pathomorphosis of depression.
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