Improvement of cerebral circulation with the help of mouth guards (orthodontic appliances)

Authors

DOI:

https://doi.org/10.61751/bmbr/2.2024.55

Keywords:

craniomandibular dysfunction, masticatory muscles, jaw joint, blood pressure, venous outflow, carotid basins

Abstract

This study was conducted to determine the effectiveness of orthodontic appliances in improving cerebral
circulation. The 24 participants of the study underwent a rheoencephalographic examination before and during the use
of mouth guards. Its results analysed the changes in blood filling and blood flow in the brain vessels and evaluated the
dynamics of treatment. According to the results of the study, insignificant, and slight positive treatment dynamics were
detected in 58.33% of the subjects, no negative dynamics were detected, and no significant changes were recorded in
41.67% of the participants. This effect of orthodontic appliances on improving cerebral circulation is explained by the
fact that by alleviating the symptoms of craniomandibular dysfunction, they affect the balance of the centre of gravity of
the skull, reduce tension and spasm in the neck muscles, and protect the joints from mechanical irritation, which helps
to reduce vascular tone and improves blood filling and blood flow in the masticatory muscles and jaw joint. The blood
filling of the chewing muscles and jaw joint has no direct connection with the blood filling of the brain vessels, as these
structures are supplied from different arteries, However, a decrease in vascular tone in the craniomandibular system and
in the muscle bed of the cervical spine can affect blood pressure reduction and venous outflow in the jaw joint, which
will indirectly improve cerebral circulation. The obtained results indicate that orthodontic problems can be factors of
deterioration of blood filling and blood flow in the vessels of the brain, so the use of mouth guards is an effective method
that should be used in the complex treatment of patients with cerebral circulation disorders

Received: 22.02.2024 | Revised: 30.04.2024 | Accepted: 28.05.2024

Author Biographies

Andriy Tymchenko, Kyiv Regional Mental Health Centre

Postgraduate Student, Medical Doctor 08296, 4 Parkova Str., Vorzel, Ukraine

Taras Garashenko, Kyiv Regional Mental Health Centre

Medical Doctor 08296, 4 Parkova Str., Vorzel, Ukraine

Tatyana Ponomarenko, Kyiv Regional Mental Health Centre

Postgraduate Student, General Director 08296, 4 Parkova Str., Vorzel, Ukraine

References

Pachì F, Turlà R, Romano A, Condò R, Giancotti A. Modification of cognitive function induced by a functional orthodontic device. Ann Stomatol. 2023;14(3):23–27. DOI: 10.59987/ads/2023.3.23-27

Sadvandi G, Kianfar AE, Becker K, Heinzel A, Wolf M, Said Yekta‐Michael S. Systematic review on effects of experimental orthodontic tooth displacement on brain activation assessed by fMRI. Clin Exp Dent Res. 2024;10(2):e879. DOI: 10.1002/cre2.879

Kariya C, Kanzaki H, Kumazawa M, Sahara S, Yoshida K, Inagawa Y, Tomonari H. Skeletal anterior open bite attenuates the chewing-related increase in brain blood flow. Dent J. 2024;12(6):161. DOI: 10.3390/dj12060161

Proff P, Schröder A, Seyler L, Wolf F, Korkmaz Y, Bäuerle T, Kirschneck C. Local vascularization during orthodontic tooth movement in a split mouth rat model – a MRI study. Biomed. 2020;8(12):632. DOI: 10.3390/biomedicines8120632

Gao Y, Min Q, Li X, Liu L, Lv Y, Xu W, Wang H. Immune system acts on orthodontic tooth movement: cellular and molecular mechanisms. Biomed Res Int. 2022;1:9668610. DOI: 10.1155/2022/9668610

Inchingolo F, Inchingolo AM, Malcangi G, Ferrante L, Trilli I, Di Noia A, et al. The interaction of cytokines in orthodontics: A systematic review. App Sci. 2024;14(12):5133. DOI: 10.3390/app14125133

Kumar I, Raghunath N, Jyothikiran H, Ravi S, Pradeep S. Influence of chronic congenital systemic disorder effects in orthodontic treatment. Int J Orthod Rehabil. 2020;11(3):123. DOI: 10.4103/ijor.ijor_22_20

Gökçe G. Complications and risks of orthodontic treatment. Dent Med J Rev. 2021;3(2):38-51.

Schwarz L, Ossmann V, Ritschl V, Stamm T, Jonke E, Bekes K. Influence of malocclusion on OHRQoL in adolescents in initial orthodontic treatment phase. Clin Oral Invest. 2024;28(5):286. DOI: 10.1007/s00784-024-05689-0

Al Nazeh AA, Alshahrani I, Badran SA, Almoammar S, Alshahrani A, Almomani BA, Al-Omiri MK. Relationship between oral health impacts and personality profiles among orthodontic patients treated with Invisalign clear aligners. Sci Rep. 2020;10(1):20459. DOI: 10.1038/s41598-020-77470-8

The World Medical Association. Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects [Internet]. [cited 2024 Apr 25]. Available from: https://www.wma.net/what-we-do/medical-ethics/ declaration-of-helsinki/

Stimmer H, Grill F, Waschulzik B, Nieberler M, Wolff KD, Kolk A. Temporal tendinitis in craniomandibular dysfunction (CMD) – does it really exist? A temporomandibular MRI investigation. RoFo. 2022;194(11):1242–49. DOI: 10.1055/a-1829-6134

Freiwald HC, Schwarzbach NP, Wolowski A. Effects of competitive sports on temporomandibular dysfunction: A literature review. Clin Oral Invest. 2021;25(1):55–65. DOI: 10.1007/s00784-020-03742-2

Asquini G, Rushton A, Pitance L, Heneghan N, Falla D. The effectiveness of manual therapy applied to craniomandibular structures in the treatment of temporomandibular disorders: Protocol for a systematic review. Syst Rev. 2021;10(1):70. DOI: 10.1186/s13643-021-01623-7

Repiso-Guardeño Á, Moreno-Morales N, Labajos-Manzanares MT, Rodríguez-Martínez MC, Armenta-Peinado JA. Does tension headache have a central or peripheral origin? Current state of affairs. Curr Pain Headache Rep. 2023;27(11):801–10. DOI: 10.1007/s11916-023-01179-2

Abdulkhaleq LA, Assi MA, Abdullah R, Zamri-Saad M, Taufiq-Yap YH, Hezmee MN. The crucial roles of inflammatory mediators in inflammation: A review. Vet World. 2018;11(5):627–35. DOI: 10.14202/vetworld.2018.627-635

de Kanter RJ, Battistuzzi PG, Truin GJ. Temporomandibular disorders: “Occlusion” matters! Pain Res Manag. 2018;1:8746858. DOI: 10.1155/2018/8746858

Manfredini D, Ahlberg J, Aarab G, Bender S, Bracci A, Cistulli PA, et al. Standardised tool for the assessment of bruxism. J Oral Rehabil. 2024;51(1):29–58. DOI: 10.1111/joor.13411

Hülse R, Wenzel A, Dudek B, Losert-Bruggner B, Hölzl M, Hülse M, Häussler D. Influence of craniocervical and craniomandibular dysfunction to nonrestorative sleep and sleep disorders. Cranio. 2019;39(4):280–86. DOI: 10.1080/08869634.2019.1630110

Wolowski A, Schneider HJ, Eger T. Dental disorders with a psychosocial background. Bundesgesundheitsbl. 2021;64(8):951–58. DOI: 10.1007/s00103-021-03369-y

Zhan Y, Yang M, Bai S, Zhang S, Huang Y, Gong F, Nong X. Effects of orthodontic treatment on masticatory muscles activity: A meta-analysis. Ann Hum Biol. 2023;50(1):465–71. DOI: 10.1080/03014460.2023.2271840

Iturriaga V, Bornhardt T, Velasquez N. Temporomandibular joint: Review of anatomy and clinical implications. Dent Clin North Am. 2023;67(2):199–9. DOI: 10.1016/j.cden.2022.11.003

Hatcher DC. Anatomy of the mandible, temporomandibular joint, and dentition. Neuroimaging Clin North Am. 2022;32(4):749–61. DOI: 10.1016/j.nic.2022.07.009

Uchino A, Suzuki J, Baba Y. Congenital external carotid-internal carotid artery anastomosis: A report of three cases and literature review. Surg Radiol Anat. 2023;45(8):995–98. DOI: 10.1007/s00276-023-03187-8

CT diagnostics of internal carotid artery aneurysms. [Internet]. [cited 2024 Apr 25] Available from: https://premium.zp.ua/ua/kt-diagnostika-anevrizm-vnutrennej-sonnoj-arterii/

Rashid A, Roatta S. Differential control of blood flow in masseter and biceps brachii muscles during stress. Arch Oral Biol. 2022;141:105490. DOI: 10.1016/j.archoralbio.2022.105490

Janal MN, Lobbezoo F, Quigley KS, Raphael KG. Stress‐evoked muscle activity in women with and without chronic myofascial face pain. J Oral Rehabil. 2021;48(10):1089–98. DOI: 10.1111/joor.13238

Fernández-Rubio EM, Radlanski RJ. Development of the human primary and secondary jaw joints. Ann Anat. 2024;251:152169. DOI: 10.1016/j.aanat.2023.152169

Zhou D, Ding JY, Ya JY, Pan LQ, Yan F, Yang Q, et al. Understanding jugular venous outflow disturbance. CNS Neurosci Ther. 2018;24(6):473–82. DOI: 10.1111/cns.12859

Rusu MC, Tudose RC, Vrapciu AD, Toader C, Popescu ŞA. Anatomical variations of the external jugular vein: A pictorial and critical review. Med. 2023;59(3):622. DOI: 10.3390/medicina59030622

Olesen ND, Egesborg AH, Frederiksen HJ, Kitchen CC, Svendsen LB, Olsen NV, Secher NH. Influence of blood pressure on internal carotid artery blood flow during combined propofol-remifentanil and thoracic epidural anesthesia. J Anaesthesiol Clin Pharmacol. 2022;38(4):580–87. DOI: 10.4103/joacp.JOACP_575_20

Neumann S, Burchell AE, Rodrigues JC, Lawton CB, Burden D, Underhill M, Kobetić MD, et al. Cerebral blood flow response to simulated hypovolemia in essential hypertension: A magnetic resonance imaging study. Hypertens. 2019;74(6):1391–8. DOI: 10.1161/HYPERTENSIONAHA.119.13229

Heit T, Derkson C, Bierkos J, Saqqur M. The effect of the physiological rest position of the mandible on cerebral blood flow and physical balance: An observational study. Cranio. 2015;33(3):195–5. DOI: 10.1179/0886963414Z.00000000063

Ulloa SS, Ordóñez AL, Sardi VE. Relationship between dental occlusion and brain activity: A narrative review. Saudi Dent J. 2022;34(7):538–43. DOI: 10.1016/j.sdentj.2022.09.001

Galindo-Moreno P, Lopez-Chaichio L, Padial-Molina M, Avila-Ortiz G, O'Valle F, Ravida A, Catena A. The impact of tooth loss on cognitive function. Clin Oral Investig. 2022;26(4):3493–500. DOI: 10.1007/s00784-021-04318-4

Kummer G, Eliades T, Koletsi D. Gender-specific treatment effects and outcomes reported in orthodontic research. A cross-sectional empirical study. Eur J Orthod. 2024;46(1):cjad073. DOI: 10.1093/ejo/cjad073

Kahn S, Ehrlich P, Feldman M, Sapolsky R, Wong S. The jaw epidemic: Recognition, origins, cures, and prevention. Biosci. 2020;70(9):759–71. DOI: 10.1093/biosci/biaa073

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Published

2024-06-17

How to Cite

Tymchenko, A., Garashenko, T., & Ponomarenko, T. (2024). Improvement of cerebral circulation with the help of mouth guards (orthodontic appliances). Bulletin of Medical and Biological Research, (2), 55–65. https://doi.org/10.61751/bmbr/2.2024.55