Endometriosisassociated breast dysplasia features of diagnosis and treatment
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2022.2.13048Keywords:
combined diseases, endometriosis, dyshormonal diseases of the mammary glands, hyperplastic processes, hyperestrogenismAbstract
Summary. The urgency of the problems of combined diseases of the reproductive system of women is due primarily the growth of this pathology worldwide. In recent years, there has been a tendency to increase the incidence of benign breast dysplasia , diagnosed in every 4 women. [ 1 ] All over the world, women in which diagnosed breast dysplasia , have an increased risk of breast cancer. Breast cancer ranks first among malignant diseases in women. The problem of benign combined pathology of the uterus and breast (GZ) is one of the most relevant in modern gynecology, due to the fact that hyperplastic processes of the uterus (GPM) and benign breast diseases (DZGZ) occupy one of the leading places in the structure of gynecological morbidity 2]
The aim of the study – to analyze the data of the modern literature to increase the effectiveness of treatment of endometriosis -associated dysplasia of the mammary glands by studying the clinic and features of early diagnosis
Materials and methods. With the help of Internet search databases, a review and analysis of materials on endometriosis -associated breast dysplasia was performed. The data of pathogenesis, diagnosis and treatment of combined pathology of the mammary glands are analyzed.
Results. The literature convincingly suggests that the processes occurring in the GH are closely related to the function of the reproductive system. It is known that GZ is not only a target for steroids, but also for pituitary hormones, thyroid hormones, adrenal glands , etc. This significantly increases the likelihood of developing pathology of the gastrointestinal tract in disorders of the reproductive system and in patients with hormone-dependent gynecological diseases. [2] IN women younger 35 years with purpose decrease radial load on the woman's body at palpatory detection of a volume new growth in a mammary gland for diagnosis it is expedient to use instead of a mammography - ultrasonography of mammary glands . The "gold standard" of breast examination is bilateral mammography, which is due to: radioresistance of mature breast tissue, low radiation dose of modern devices, high efficiency of diagnosis of asymptomatic malignant tumors: 85–90 %. Evidence-based data confirm the effectiveness of herbal and homeopathic remedies. In the treatment of mastopathy and other hypertrophic dysplasia in women; depending on the clinical form of the disease, herbal medicine provides a significant improvement or recovery of 40–87 % of patients [3]
Conclusions. Summarizing all the above, we can safely say that understanding the pathogenesis, algorithms for diagnosis and treatment of edometriosis -associated breast dysplasia will help obstetricians provide qualified care to patients, improve the quality of life of women and prescribe the most effective treatment for this pathology.
References
Kruk OY. [The problem of combined diseases of the reproductive system of women]. Visn Vinnyts nats univer. 2019;4: 733-39. Ukrainian.
Sheligin MS. [Combined benign pathology of the uterus and breasts in women of reproductive age: diagnosis and treatment tactics]. Zdorov zhenshch. 2014;9(95): 158-60. Ukrainian.
Radzinsky VE, Ordyants IM, Maslennikova MN, Pavlova EA. [Breasts and gynecological diseases: from common pathogenetic views to practical solution]. Reprodukt endokrinol. 2014;2(16): 72-80.
Likhachev VK. Gynecology: a guide for doctors. [Гінекологія : керівництво для лікарів] Vinnytsia: Nova Knyha; 2018. Ukrainian.
Voloshina NN, Pashchenko SN, Shchurov NF. [Non-hormonal therapy of proliferative processes of the breast and endometrium]. Zdorov zhenshch. 2013;1: 94-8. Russian.
Golovko TS. [Mastodynia in the practice of oncomammology]. Z turbotoiu pro zhinku. 2015;3 (60): 6-9. Ukrainian.
Zhuk SI. [Benign dysplasia of the mammary glands: a review of recent studies]. Zhin likar. 2016;6 (67): 34-8. Ukrainian.
Likhachev VK. Hormonal diagnostics in obstetrics and gynecology. [Гормональна діагностика в акушерстві та гінекології] Poltava: Dyvosvit; 2015. Ukrainian.
Likhachev VK, Dobrovolskaya LM, Semenyuk LM, Yaremchuk LV. Obstetrics and gynecology: Workshop. [Акушерство та гінекологія: практикум] Poltava: Dyvosvit; 2014. Ukrainian.
Shurpiak S.О. Substantiation of pathogenetic disease of patients with fibrocystic disease. Zdorovia zhin. 2015;103(7): 147-50. Ukrainian.
Carauleanu A, Socolov R, Rugina V. Comparisons between the non-proliferative and proliferative therapy in fibrocystic mastosis. Rev Med Chir Soc Med Nat Iasi. 2016;120(2): 321-7.
Charlson M, Wells MT, Ullman R, King F, Shmukler C. The Charlson comorbidity index can be used prospectively to identify patients who will incur high future costs. PLoS ONE. 2014;9(12): e112479 DOI:10.1371/journal.pone. 0112479
Claus EB, Stowe M, Carter D. Family history of breast and ovarian cancer and risk of breast carcinoma in situ. Breast Cancer Res. Treat. 2013;78(1): 7-15.
Czernobilsky B. Endometriosis. In H. Fox (Ed.). Obstetrical and Gynecological Pathology. New York: Churchill Living stone; 2015.
Villiers de TJ, Pines A, Panay N, Gambacciani M, Archer DF, Baber RJ, Sturdee DW. Updated 2013 International Menopause Society recommendations on menopausal hormone therapy and preventive strategies for midlife health. Climacteric. 2013;16(3): 316-37. DOI: 10.3109/13697137.2013.795683.
Gold EB, Crawford SL, Avis NE, Crandall CJ, Matthews KA, Waetjen LE, Harlow SD. Factors related to age at natural menopause: longitudinal analyses from SWAN. Am J Epidemiol. 2013;178.
Gorban NYe, Zadorozhna TD, Vovk IB, Zhulkevych IV. Morphological features of uterine polyps in females of reproductive age. Visn nauk doslidzh. 2019;2: 47-52.
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