TYPE 2 DIABETES MELLITUS AND ITS COMORBIDITY
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2020.4.11827Keywords:
type 2 diabetes mellitus, comorbidity, prevalenceAbstract
Summary. Diabetes is a complex health problem that has caused international concern over the past few decades.
The aim of the study – to analyze the literature sources on comorbid pathologies that are combined with the type 2 diabetes mellitus (T2DM).
Materials and Methods. Scientific publications for the last decade was examined in the study, which are available in the Internet, the key words were “type 2 diabetes mellitus”, “comorbidity”, “concurrent diseases”.
Results. Multimorbidity, presence of two or more chronic diseases [8], is characteristic for patients with T2DM, which makes multimorbidity an important clinical priority in this population. Because of similar risk factors such as obesity, endothelial dysfunction, vascular inflammation and dyslipidemia, patients with T2DM have higher risk of cardiovascular complications, kidney disease and hypertension. Patients with T2DM have also higher risk of depression, gastrointestinal disease, thyroid disease, and chronic obstructive pulmonary disease. T2DM is closely associated with overweight and low physical activity. Another complication of T2DM is erectile dysfunction. Although most of the scientific literature highlights development of T2DM in patients with pancreatitis, there is an inverse relations: exocrine insufficiency of the pancreas is found in 35 % of patients with T2DM. In addition, high level of vitamin D deficiency is another factor associated with both obesity and type 2 diabetes mellitus.
Conclusions. Analysis of literature sources indicates significant prevalence of comorbidity in patients with type 2 diabetes mellitus, which justifies the necessity of more detailed and comprehensive study of the mechanisms of combined pathology, peculiarities of course, methods of precaution, treatment and prevention of complications.
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