STATE OF GASTRIC MUCOSA ACCORDING TO HIGH RESOLUTION ENDOSCOPY WITH NARROW-BAND IMAGING IN PATIENTS WITH ATROPHIC GASTRITIS COMBINED WITH THYROID DISEASES
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2020.3.11346Keywords:
precancerous changes of the stomach mucosa, endoscopic examination, atrophic gastritis, intestinal metaplasia, thyroid glandAbstract
Summary. Cancer and precancerous stomach pathology are an important problem in medicine today. It is important to identify additional risk factors for the development of stomach cancer. Single studies have shown the relationship between the development of atrophic gastritis and thyroid diseases.
The aim of the study – to determine the peculiarities of the gastric mucosa structure in patients with chronic atrophic gastritis, depending on the presence of thyroid gland structural changes.
Materials and Methods. 45 patients with atrophic gastritis underwent upper endoscopy using the endoscope with high resolution and narrow-band imaging modes and ultrasound examination of the thyroid gland. According to the ultrasound examination results, the patients were divided into the following groups: I – patients with focal changes, II – patients with diffuse changes of the thyroid gland, the comparison group – patients without changes in the thyroid gland. Statistical and correlation analyzes were carried out.
Results. It was revealed an increase in the prevalence of erythematous changes, a tendency to an increase in the frequency of nodular relief of the gastric mucosa in patients with focal lesions in the thyroid gland, an increase in the frequency of stomach erosions, ulcers and hemorrhages in patients with structural changes in the thyroid gland, a significant increase in the frequency of diffuse spread of gastric mucosa intestinal metaplasia in patients with focal thyroid gland changes, compared with patients with diffuse thyroid gland changes or without them; dysplasia of the gastric mucosa was detected only in patients with structural thyroid gland changes and more often in patients of group I (p> 0.05). The obtained differences were confirmed by correlation analysis.
Conclusions. In patients with atrophic gastritis combined with thyroid pathology (diffuse and focal), a significant increase of the gastric mucosa structural changes, including precancerous ones, was revealed, which is confirmed by the results of a correlation analysis.
References
Dinis-Ribeiro M, Areia M, de Vries AC, Marcos-Pinto R, Monteiro-Soares M, O'Connor A, et al. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED). Endoscopy. 2012;44(1): 74-94. DOI:10.1055/s-0031-1291491. DOI: https://doi.org/10.1055/s-0031-1291491
Pimentel-Nunes P, Libânio D, Marcos-Pinto R, Areia M, Leja M, Esposito G, et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy. 2019;51(4): 365-88. DOI: 10.1055/a-0859-1883. DOI: https://doi.org/10.1055/a-0859-1883
Sugano K, Tack J, Kuipers EJ, Graham DY, El-Omar EM, Miura S, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9): 1353-67. DOI: 10.1136/gutjnl-2015-309252. DOI: https://doi.org/10.1136/gutjnl-2015-309252
Stepanov YuM, Simonova OV, Mosiichuk LM, Petishko OP. [Modern endoscopic criteria for stratification of patients with atrophic gastritis in the development of precancerous changes of the stomach]. Patholohiia. 2018;15(3): 346-53. DOI: 10.14739/2310-1237. 2018.3.151857. Ukrainian. DOI: https://doi.org/10.14739/2310-1237
Rodriguez-Castro KI, Franceschi M, Miraglia C, Russo M, Nouvenne A, Leandro G, et al. Autoimmune diseases in autoimmune atrophic gastritis. Acta Biomed. 2018;89(8-S): 100-3. DOI: 10.23750/abm.v89i8-S.7919.
Cellini M, Santaguida MG, Virili C, Capriello S, Brusca N, Gargano L, et al. Hashimoto's Thyroiditis and Autoimmune Gastritis. Front Endocrinol (Lausanne). 2017;8: 92. DOI: 10.3389/fendo.2017.00092. DOI: https://doi.org/10.3389/fendo.2017.00092
Kandemir EG, Yonem A, Narin Y. Gastric carcinoma and thyroid status. J Int Med Res. 2005;33(2): 222-7. DOI: 10.1177/147323000503300210. DOI: https://doi.org/10.1177/147323000503300210
Venerito M, Radünz M, Reschke K, et al. Autoimmune gastritis in autoimmune thyroid disease. Alimentary Pharmacology & Therapeutics. 2015;41(7): 686-93. DOI: 10.1111/apt.13097. DOI: https://doi.org/10.1111/apt.13097
Stepanov YuM, Simonova OV, Mosiichuk LM. [Modern endoscopic technologies of precancerous stomach conditions diagnostics: problems and possibilities]. Нastroenterolohiia. 2017:51(1): 64-72. DOI: 10.22141/2308-2097.51.1.2017.97873. Ukrainian. DOI: https://doi.org/10.22141/2308-2097.51.1.2017.97873
Comprehensive Atlas of High Resolution Endoscopy and Narrowband Imaging. Editor J. Cohen. Blackwell Publishing, 2009. Translation from English, edited by A.A. Budzinsky. Moscow: Logosphere; 2012. ISBN 978-5-98657-028-0. Russian.
East JE, Vleugels JL, Roelandt P, Bhandari P, Bisschops R, Dekker E, et al. Advanced endoscopic imaging: European Society of Gastrointestinal Endoscopy (ESGE) Technology Review. Endoscopy. 2016;48(11): 1029-45. DOI: 10.1055/s-0042-118087. DOI: https://doi.org/10.1055/s-0042-118087
Pimentel-Nunes P, Dinis-Ribeiro M, Soares JB, Marcos-Pinto R, Santos C, Rolanda C, et al. A multicenter validation of an endoscopic classification with narrow band imaging for gastric precancerous and cancerous lesions. Endoscopy. 2012;44(3): 236-46. DOI: 10.1055/s-0031-1291537. DOI: https://doi.org/10.1055/s-0031-1291537
Cho JH, Jeon SR, Jin SY. Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis of Helicobacter pylori gastritis, precancerous gastric lesion, and neoplasia. World J Clin Cases. 2020;8(14): 2902-16. DOI:10.12998/wjcc.v8.i14.2902. DOI: https://doi.org/10.12998/wjcc.v8.i14.2902
White JR, Sami SS, Reddiar D, Mannath J, Ortiz-Fernández-Sordo J, Beg S, et al. Narrow band imaging and serology in the assessment of premalignant gastric pathology. Scandinavian Journal of gastroenterology, 2018;53(12): 1611-8. DOI: 10.1080/00365521.2018.1542455. DOI: https://doi.org/10.1080/00365521.2018.1542455
Uedo N, Ishihara R, Iishi H, Yamamoto S, Yamamoto S, Yamada T, et al. A new method of diagnosing gastric intestinal metaplasia: narrow-band imaging with magnifying endoscopy. Endoscopy. 2006 Aug;38(8): 819-24. DOI: 10.1055/s-2006-944632. DOI: https://doi.org/10.1055/s-2006-944632
Graham DY, Rugge M, Genta RM. Diagnosis: gastric intestinal metaplasia - what to do next? Curr Opin Gastroenterol. 2019;35(6): 535-43. DOI:10.1097/MOG.0000000000000576. DOI: https://doi.org/10.1097/MOG.0000000000000576
