NEW APPROACHES TO THERAPEUTIC CORRECTION OF BURN SCAR DEFORMATION OF THE SKIN
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2020.2.11276Keywords:
laser genesis of scars, post-burn, hypertrophic keloid scars, prevention of scar formationAbstract
Summary. Deformations of the skin after a burn injury cause the development of a persistent violation of the protective tissue barrier with the development of adaptive immunological dysfunction and remain an urgent problem of finding effective ways to eliminate changes.
The aim of the study – to evaluate the effectiveness of the correction of burn scars at various degrees of skin damage using laser genesis and to establish a correlation between the formation of pathological postoperative scars and the timely use of a laser device in an integrated approach Nd Yag 1064 nm Cutera (USA).
Materials and Methods. There were 49 patients under observation who sought help at the Clinic of Laser Cosmetology "Monet" (Ternopil). The examination included 25 patients with fresh burn scars, 12 with formed scars, 12 with obsolete hypertrophic and keloid scars in the comparison group.
Results. Our studies have shown the effectiveness of the use of a complex effect of laser genesis using a Nd Yag 1064 nm Cutera laser device (USA) for the treatment of burn scars of the skin, facilitated the restoration of tissues with an identical original anatomical structure with aesthetic and functional attributes inherent in intact tissue.
Conclusions. Correction of scars of different maturation periods using the laser genesis procedure with the Nd Yag 1064 nm Cutera laser (USA) proved to be effective as an independent therapy for both fresh and obsolete scars in combination with cryodestruction followed by xenoplasty and injections of steroid drugs.
References
Reinke JM, Sorg H. Wound repair and regeneration. Eur Surg Res Review Articles, Systematic Reviews and Meta-Analyses 2012;49: 35-43. DOI: 10.1159/000339613. DOI: https://doi.org/10.1159/000339613
Shao-wei Yang, Zhi-jun Geng, Kui Ma, Xiao-yan S. Comparison of the histological morphology between normal skin and scar tissue. Journal of Huazhong University of Science and Technology. Medical Sciences. 2016;36: 265-9. Available from: https://link.springer.com/article/10.1007/s11596-016-1578-7 - citeas. DOI: https://doi.org/10.1007/s11596-016-1578-7
Kaufmann R, Beier C. Laser skin ablation: An update on aesthetic and medical indications. Medical Laser Application. 2004;19(4): 212-22. DOI: 10.1078/1615-1615-00145 DOI: https://doi.org/10.1078/1615-1615-00145
Bohannon J, Cui W, Cox R. Prophylactic treatment with fms-like tyrosine kinase-3 ligand after burn injury enhances global immune responses to infection. J Immunol. 2008;1,180(5): 3038-48.
Shumaker P.R. Laser treatment of traumatic scars: a military perspective Seminars in Cutaneous Medicine and Surgery. 2015;34. DOI: 10.12788/j.sder.2015.0123 DOI: https://doi.org/10.12788/j.sder.2015.0123
Stenko AH, Kruhlova LS, Shmatova AA, Techyeva SH. [Conservative treatment of forming scars: a review of modern technologies]. Vestnyk estetycheskoy meditsyny. 2014;13(2), 42-50. Russian.
Jiang DY, Fu XB, Chen W, Sun TZ. Relationship of overexpression of angiogenesis factors and their receptors with invasive growth of keloids. Zhonghua Zheng Xing Wai Ke Za Zhi. 2004;20(2): 128-31.
Philipp CM, Scharschmidt D, Berlien P. Laser treatment of scars and keloids – How we do it. Medical Laser Application. 2008;23(2): 79-86 DOI: https://doi.org/10.1016/j.mla.2008.01.005
Tudorf EH, Danielson PL, Paulsen IF. Non-ablative fractional laser provides long-term improvement of mature burn scars – A randomized controlled trial with histological assessment [published online ahead of print August 22, 2014. Lasers Surg Med. DOI: 10.1002/lsm.22289]. DOI: https://doi.org/10.1002/lsm.22289
Anderson RR, Donelan MB, Hivnor C. Laser treatment of traumatic scars with an emphasis on ablative fractional laser resurfacing: consensus report. JAMA Dermatol. 2014;150(2): 187-93. DOI: https://doi.org/10.1001/jamadermatol.2013.7761
Greenhalgh DG. The role of apoptosis in wound healing. Int J Biochem Cell Biol 1998;30: 1019-30. DOI: https://doi.org/10.1016/S1357-2725(98)00058-2
