Autonomous regulation of heart rate in conditions of blocking the beta 1-adrenergic receptors in associative cortex of young rats with hypoxic exposure
DOI:
https://doi.org/10.11603/mcch.2410-681X.2015.v17.i3.5057Abstract
The literature discusses modulation of beta-adrenergic receptors sensitivity of the cerebral cortex under changed
conditions for the functioning of the body. However, very little data on the effect of the hypoxic environment to the
sensitivity of beta-adrenergic receptors of the cerebral cortex in a young body, which possible to investigate in
experiments on rats. The aim of the experiment was to determine the functional consequences of the exclusion of
beta1-adrenergic receptors in the associative cortex in young rats after incubation in hypoxic environment under
conditions of low atmospheric pressure. Blocking the beta1-adrenergic receptors in young rat’s associative cortex
can significantly offset the regulatory effects on heart rate that occurred during incubation in the hypoxic environment
under conditions of low atmospheric pressure. Hypoxic effect in young rats resulted in a significant decrease in
sensitivity beta1-adrenergic receptors in the associative cortex.
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