FEATURES OF GENERAL BLOOD ANALYSIS INDICATORS IN THE COMORBID COURSE OF COMMUNITY-ACQUIRED PNEUMONIA ASSOCIATED WITH COVID-19 AND ARTERIAL HYPERTENSION
DOI:
https://doi.org/10.11603/mcch.2410-681X.2024.i2.14765Keywords:
community-acquired pneumonia, arterial hypertension, COVID-19, general blood test, hemogram, leukogram, platelets, risk of fatal outcomeAbstract
Introduction. Current research shows that arterial hypertension (AH) is the most common comorbidity among patients with COVID-19 pneumonia, which accounts for approximately 30% of the population. A study conducted in Europe showed that concomitant pathologies (chronic respiratory and cardiovascular diseases, dementia, cerebrovascular diseases, human immunodeficiency virus, chronic kidney and liver diseases) increase the risk of community-acquired pneumonia by 2-4 times. However, it is still unclear whether there is a direct relationship between COVID-19 pneumonia and hypertension.
The aim of the study – to analyze the parameters of the general blood test in patients with community-acquired pneumonia associated with COVID-19 and arterial hypertension depending on the severity of the pneumonia.
Research Methods. A retrospective study of the medical records of 191 patients who were hospitalized for community-acquired pneumonia (CAP) with a negative smear test result for the SARS-CoV-2 virus was conducted. Patients were divided into 3 groups depending on the severity of pneumonia. The parameters of the general blood analysis were determined on the Yumizen H500 CT automatic hematology analyzer.
Results and Discussion. In patients with community-acquired pneumonia associated with COVID-19 and arterial hypertension of the 1st degree, the values of erythrocytes and platelets were found to be probably higher in patients with IV risk of fatal outcome by 16.74 % and 11.54 %, respectively, as well as ESR in III and IV classes risk of fatal outcome by 40.00 % and 25.00 %, respectively, in relation to these groups without hypertension. In patients with community-acquired pneumonia associated with COVID-19 and arterial hypertension of the 1st degree, leukocyte values were found to be probably higher in patients of the II, III and IV classes of the risk of fatal outcome by 26.58 %, 26.14 % and 15.63 %, respectively, in relation to such groups without hypertension, which is associated with an increase in segmented neutrophils against the background of a decrease in lymphocytes.
Conclusion. The obtained results indicate more pronounced changes in the parameters of the general blood analysis in patients with COVID-19 associated pneumonia, which was combined with hypertension.
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