OBTAINING AND STANDARDIZATION OF CONDENSED JUICE FROM CRANBERRIES MARSH FRUITS

  • K. M. Yatsyuk IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY
  • M. I. Fedorovskaya IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY
  • S. M. Marchyshyn I. HORBACHEVSKY TERNOPIL STATE MEDICAL UNIVERSITY
  • L. I. Budniak I. HORBACHEVSKY TERNOPIL STATE MEDICAL UNIVERSITY
  • L. V. Slobodianiuk I. HORBACHEVSKY TERNOPIL STATE MEDICAL UNIVERSITY
Keywords: cranberry marsh, condensed juice, biologically active substances, spectrophotometry, juice technology

Abstract

Introduction. Cranberries marsh fruits is a valuable raw material for the development of phyto preparations, which are used in the treatment of urinary tract infections (UTI), colds and dental diseases. Biologically active substances (BAS) contained in this raw material and can exhibit antimicrobial properties to the major uropathogenic strains of microorganisms. Obtaining condensed juice from Cranberries marsh fruits is promising, when developing solid dosage forms for use in urology.

The aim of the study – to develop a technology obtaining and standardize condensed juice from Cranberries marsh fruits.

Research Methods. Freshly prepared and concentrated juice from Cranberries marsh fruits was analyzed by the following parameters: description, pH, dry residue (fresh juice), identification and quantitative determination of the main groups of biologically active substances.

Results and Discussion. The optimum technology of reception of condensed juice from Cranberries marsh fruits was developed during conducted researches. The basic quality indicators are determined for the fresh condensed juice.

Conclusions. The optimum method for obtaining fresh juice from Cranberries marsh fruits is substantiated. Its quality criteria are defined: appearance, pH from 2.46 to 2.5, identification by Liquid chromatography-mass spectometry, color reactions and quantitative determination by titrimetry and ultraviolet spectrophotometry: organic acids – not less than 0.78 %, polyphenols – not less than 1.8 %, tannins – not less than 0.39 %, proanthocyanidine – not less than 0.33 %. In obtaining concentrated juice from Cranberries marsh fruits, it is found that the optimal method of thickening is infra-red drying at 35–40 ° С up to 30 % of the initial mass. The main indicators of quality of condensed juice from Cranberries marsh fruits are determined as description, pH 2.46 to 2.5 and quantitative content of organic acids – not less than 2.37 %, polyphenols – not less than 5.37 %, tannins – not less than 1.06 %, proanthocyanidines – not less than 0.95 %. The technological scheme of obtaining condensed juice from Cranberries marsh fruits was developed.

References

Nastanova Yevropeyskoi asotsiatsii urolohiv iz likuvannia infektsii sechovykh shliakhiv [The European Association of Urology Guideline about urinary tract infections treatment]. EAU, 2012,2013 [in Ukrainian].

Cavanagh, H.M.A., Hipwell, M., & Wilkinson, J.M. (2003) Antibacterial activity of berry fruits used for culinary purposes. J. Med. Food., 6 (1), 57-61.

Yatsiuk, K.M., Fedorovska M.I. & Kutsyk R.V (2017). Vyvchennia antymikrobnoi dii zhushchenoho soku z plodiv zhuravlyny bolotnoi (Vaccinium oxycoccos L.) [The investigation of the cranberry concentrated juice antimicrobial activity]. Farmatsevtychnyi zhurnal ‒ Pharmaceutical Journal, 1, 84-92 [in Ukrainian].

Guay, D.R. (2009) Cranberry and urinary tract infections. Drugs, 69 (7), 775-807. doi: 10.2165/00003495-200969070-00002

LaPlante, K.L., Sarkisian, S.A., Woodmansee, S., Rowley, D.C., & Seeram, N.P. (2012). Effects of cranberry extracts on growth and biofilm production of Escherichia coli and Staphylococcus species. Phytother. Res., 26 (9), 1371-1374. doi: 10.1002/ptr.4592

Rafsanjany, N., Senker, J., Brandt, S., Dobrindt, U. & Hensel, A. (2015). In vivo consumption of cranberry exerts ex vivo antiadhesive activity against FimH-dominated uropathogenic Escherichia coli: A combined in vivo, ex vivo, and in vitro study of an extract from Vaccinium macrocarpon. J. Agric. Food Chem., 63 (40), 8804-8818. doi: 10.1021/acs.jafc.5b03030

Solodovnychenko, N.M., Zhuravlov, M.S. & Kova­lov, V.M. (2001). Lіkarska roslynna syrovyna ta fіtopre­paraty: posib. z farmakohnozii z osnovamy biokhimii likarskykh roslyn [Medicinal plants and herbal medicines, training manual. Pharmacognosy with basic biochemistry of medicinal plants]. Kharkiv: Vyd-vo NFAU Zoloti storinky [in Ukrainian].

(2015). Derzhavna Farmakopeia Ukrainy: v 3 t. Derzhavne pidpryiemstvo “Ukrainskyi naukovyi farmako­peinyi tsentr yakosti likarskykh zasobiv” [State Pharma­copeia of Ukraine: in 3 vol. / State Enterprise “Ukrainian Scientific Pharmacopoeial Centre of Medicinal drugs Quality]. Kharkiv: Derzhavne pidpryiemstvo “Ukrainskyi naukovyi farmakopeinyi tsentr yakosti likarskykh zasobiv” [in Ukrainian].

Published
2019-07-11
How to Cite
Yatsyuk, K. M., Fedorovskaya, M. I., Marchyshyn, S. M., Budniak, L. I., & Slobodianiuk, L. V. (2019). OBTAINING AND STANDARDIZATION OF CONDENSED JUICE FROM CRANBERRIES MARSH FRUITS . Medical and Clinical Chemistry, (2), 55-60. https://doi.org/10.11603/mcch.2410-681X.2019.v.i2.10294
Section
ORIGINAL INVESTIGATIONS