INFLUENCE OF EXO- AND ENDOGENOUS FACTORS ON PANCREAS MORPHOLOGY
(LITERATURE REVIEW)
DOI:
https://doi.org/10.11603/bmbr.2706-6290.2020.4.11828Keywords:
pancreas, morphofunctional changes, exogenous and endogenous factorsAbstract
Summary. The article is devoted to the study and detailed analysis of articles and scientific literature on the morphofunctional features of pancreatic remodeling with various effects on the body. The pancreas, along with other glands involved in the regulation of body functions, so the violation of its activities under the influence of various factors is a topical issue.
The aim of the study – to learn and analyze the current data of scientists on the influence of various factors on the reorganization of the pancreas and to identify new promising morphological views on the study of the organ.
Materials and Methods. The material for the article was scientific publications in recent years on the influence of various factors on the morphological features of the pancreas.
Results. The article considers the literature on the effects on the pancreas of salts of heavy metals, drugs and toxic substances, alcohol, smoking, starvation, obesity, gravity, oxygen starvation, hyperoxygenation, hypothermia, dehydration, iodine deficiency, drugs, and viral infections. under the action of electric current. However, a small number of scientific sources are devoted to the influence of thermal factors on the condition of the pancreas.
Conclusions. According to the analysis of literature sources to date, the influence of a significant number of external and internal factors on the pancreas has been studied. However, the effect of thermal skin burns on the morphofunctional state of the gland in modern scientific articles is almost non-existent, so this problem requires further research.
References
Gushchin Ya, Shedko V, Muzhikyan A, Makarova M, Makarov V. [Comparative morphology of the pancreas of experimental animals and humans]. Lab zhyvot dlya nauch iss. 2018;(3): 33-48. Russian.
Kravets OV. [Morphological and readaptational changes in the pancreas under the influence of heavy metal salts [abstract]. Kharkiv ‘‘Kharkiv National Med. University’’; 2011. 25 p. Ukrainian.
Lebedev SV, Gavrish IA, Gubaydullina IZ. [Different chrome sources influence on morphobiochemical indicators and activity of digestive enzymes in wistar rats]. Selsk biol. 2019; 54(2):304-315. DOI: 10.15389/agrobiology.2019.2.304rus. Russian.
Vorontsova ZA, Gureev AS. [Biotffects exocrine and endocrine parenchyma organs on depleted uranium]. The journal of scientific articles “Health & education millennium”. 2013; 15(1-4): 250-252. Russian.
Zinenko DYu, Tverdokhlib IV. [Ultrastructural characteristics of the hemomicrocirculatory bed and parenchymatous-stromal elements of the pancreas and liver in a model of acute pancreatitis using different doses of sodium taurocholate]. Morphologiya. 2020;14(1): 23-34. DOI: https://doi.org/10.26641/1997-9665.2020.1.23-34. Ukrainian.
Beregovenko IM, Zinenko DYu, Tverdokhlib IV. [Microcirculation and pathomorphological changes of pancreas in development of an experimental acute pancreatitis in rats]. Visn probl boil i med. 2016;1(2): 331-4. Ukrainian.
Ponomarenko NV. [Influence of amaranth seeds on the composition and peroxidation of lipids in the pancreas of quails under the action of nitrates [abstract]. Bila Tserkva State Agrarian University of the Ministry of Agrarian Policy of Ukraine; 2007. 23p. Ukrainian.
Mykhalevych MM. [Morphological changes of organs under the influence of opioid]. Klin anat i oper khirur. 2019;18(4): 133-45. DOI: 10.24061/1727-0847.18.4.2019.21. Ukrainian.
Popyk PM. [Microstructure characteristics of pancreas white rat under influence opioid]. Visn probl boil i med. 2014.2(3): 310-3. Ukrainian
Shabdarbaeva DM, Sayakenov NB, Alimbekova BR, Lepesbaev MN. [Immunomorphological characteristics of the pancreas when exposed to drugs]. Sovrem med: actual vopr. 2015;2(38): 90-102. Russian.
Oshmyanska NY, Galinsky AA, Gaidar YA. [Peculiarities of death and regeneration of pancreas cells at early stages of alcoholic chronic pancreatitis]. Visnyk Dnipropet univer biol med. 2014;(5(2)): 138-42. DOI:10.15421/021426. Russian.
Klishch. IM, Nesteruk SO. [The effect of chronic ethanol intoxication on the reproductive system]. Visn med i boil dosl. 2020;3(5): 161-6. DOI: 10.11603/bmbr.2706-6290.2020.3.11527. Ukrainian.
[Medical online directory. Smoking in pancreatitis – the effects of tobacco on the pancreas [Internet]. [cited 2021 Feb 11]; Available from: https://virgo.org.ua/index.php/gastroenterologiya/10352-kurinnja-pri-pankreatiti-vpliv-tjutjunu- Ukrainian.
Leshchenko IV. [Structural and functional state of the pancreas under conditions of obesity [abstract]. Taras Shevchenko National University of Kyiv, Ministry of Education and Science of Ukraine, 2020. 21p. Ukrainian.
Grigorova NV, Khmelevska AP. [The state of pancreatic β-cells of adult and old mice after exposure to acute starvation and atropine]. Aktual pyt biol, ekol i khim. 2016;12(2) : 33-40. Ukrainian.
Yanko RV. [Morphological changes pancreas after of melatonin’s effect in different seasons]. Fisiol zhurn. 2016;62(6): 88-94. Ukrainian.
Davydova NV. [Characteristics of influence produced by melatonin on some biochemical parameters of rat blood plasma at alloxan diabetes]. Aktual probl such med. 2016;16(4(1)): 242-4. Russian.
Zakharova IV. [The structure of the pancreas after exposure to gravitational overload theory]. Morfol. 2006;129(1): 60-5. Russian.
Slynko TN, Velikorodova MYa, Zarechnova NN. [Structured pancreas changes in deadaptation process to high altitude]. Vest Sib med. 2009;(1(2)): 69-72. Russian.
Barkhina TG, Donskoy MV, Savishchev AV. [Pancreas ultrastructure under conditions of changing gas environment]. Sat. scientific. proceedings of the All-Russian jubilee conference of pathologists dedicated to the 100th anniversary of prof. P.G. Podzolkova. Krasnoyarsk: 2008; 94-95. Russian.
Savishchev AV, Moldavskaya AA. Pancreatic morphogenesis at the stages of ontogenesis in experimental modeling under the influence of stress factors. [Морфогенез поджелудочной железы на этапах онтогенеза при экспериментальном моделировании под воздействием стрессогенных фактор] Moscow: Astrakhan; 2011. Russian.
Stepanyan YuS. [Morphofunctional equivalents of reaction pancreas on general overcooling]. Probl ekspert v med. 2008;(2): 22-4. Russian.
Doroshkevych SV, Pyvchenko PG, Doroshkevich EY. [Experience in cryomodelling pancreatic pathology]. Eksperim i klin gastroent. 2010;(8): 52-5. Russian.
Kurzanov AN, Zabolotskikh NV, Myasnikova VV, Shestopalov AV. [Pathophysiological aspects of experimental cryomodeling of pathological conditions of the pancreas]. Kuban nauchn med zhurn. 2016;6(116): 97-100. Russian.
Savishchev AV. [Electron-microscopic characteristics of the pancreas with a change in temperature]. Izvest vyssh ucheb zav. Povolzh reg. Med nauki. 2010;4(16): 11-7. Russian.
Kovchun VYU, Sikora VZ, Lindin MS, Sikora VV. [Histomorphometric assessment of changes in the parenchyma of the pancreas under the influence of hyperosmolar dehydration]. Bukovyn med visn. 2020;24(2): 52-6. Ukrainian.
Lazarenko LV, Kosareva PV, Samodelkin EI, Khorinko VP. [Pathomorphological changes in rat pancreatic tissues caused by long administration of nimesulide]. Perm med zhurn. 2016;ХХХІІІ(4): 78-81. Russian.
Viktorov OP. [Adverse reactions to medical drugs and the pancreas]. Zdorov Ukr. 2009; Thematic number: 56-57. Ukrainian.
Ostapenko OV, Chaikovsky YuB. [Ultrastructural changes of rats pancreas acynocytes in the dynamics of congenital hypothyroidism development]. Biomed. 2014;(1): 38-44. Russian.
Utekhin VJ. [Pancreatic epithelium under the hypothyroid condition]. Vest S of St. Petersburg University. 2015;(2): 89-111. Russian.
Abramovich АА, Styazhkina SN, Sharipova АH. [Clinical case in surgical practice: acute idiopathic pancreatitis, complicated by multiple abscesses of the cerebral hemispheres]. Nauch zhurn dlya stud i prepod. 2021;(1): 125-30. Russian.
Ametov AS, Pugovkina YaV. [Glucose homeostasis and metabolic flexibility in healthy individuals]. Endokrinol: nov, mnen, obuch. 2020;9(4): 12-22. DOI: https://doi.org/10.33029/2304-9529-2020-9-4-12-22. Russian.
Ubaydullaeva VU, Fayazov AJ, Tulyaganov DB, Vervekina TA, Kamilov UR. [Morphological changes of internal organs in electrical trauma in laboratory animal models]. Vest ekstren med. 2019;12(1): 54-61. Russian.
Zubritsky MG. [Morphological changes in the pancreas in acute herpetic meningoencephalitis]. Zhurn Grodno gos med univer. 2006;(1): 53-6. Russian.
Babinets LS, Scheigen OR. [Infectious factors in the formation of pathology of the pancreas. Medical newspaper "Health of Ukraine of the 21st century". [Internet]].2017 [cited 2021 Feb 11]; Jan 1 (398). Available from: http://health-ua.com/article/25968-nfektcjn-chinniki-uformuvann-patolog-pdshlunkovo-zalozi. Ukrainian.
Babenko АYu, Laevskaya MYu. [Diabetes mellitus and COVID 19. How are they connected? Current strategy of fight]. Arterialnaya gipertenziya. 2020;26(3): 304-11. DOI:10.18705/1607-419X-2020-26-3-304-311. Russian.
Sabirova A. Mamytova A. Akramov I, Sabirov I. [New coronavirus infection (covid-19) and diabetes mellitus: a dentist's view]. The Scientific Heritage. 2021;(58):44-51. Russian.
Elbassuoni EA, Abdel Hafez SM. Impact of chronic exercise on counteracting chronic stress-induced functional and morphological pancreatic changes in male albino rats. Cell Stress Chaperones. 2019;24(3): 567-80. DOI: 10.1007/s12192-019-00988.
Hew J, Parungao R, Shi H, Tsai K, Kim S, Ma D, Malcolm J, Li Zh,. Maitz P. Wang Y. Mouse models in burns research: Characterisation of the hypermetabolic response to burn injury. Burns. 2020;46(3): 663-74. DOI: https://doi.org/10.1016/j.burns.2019.09.014
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